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Biologists at Tufts University discover 1 reason why chromosomes break, often leading to cancer

and Zhang found the longer the AT-repeat, the more the replication process was stalled, something they would like to follow up on with further research.

"We think the longer the repeat, the more the abnormal DNA structure forms, and the more fragile your chromosome is, but we haven't completely been able to nail that down," Freudenreich said. "It would be interesting to know, would people with longer repeats be more prone to deleting that tumor suppressor gene and getting cancer as a result" We have made this correlation and we'd like to know if it has a medical consequence."


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Contact: Suzanne Miller
suzanne_c.miller@tufts.edu
617-627-4703
Tufts University
2-Aug-2007


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