HOME >> BIOLOGY >> NEWS
Bisexual fruit flies show new role for neurochemical

Fruit flies' ability to discern one sex from another may depend on the number of receptors on the surface of nerve cells, and the number of receptors is controlled by levels of a ubiquitous brain chemical, University of Illinois at Chicago researchers have found.

Everything from the ability to concentrate, perceive and learn to debilitating illnesses such as amyotrophic lateral sclerosis, muscular dystrophy, post-traumatic stress syndrome and schizophrenia is influenced by the number of receptors on nerve cells. The more receptors each cell has at its communication points, or synapses, the better that messages are carried through the brain.

A UIC research team led by David Featherstone, assistant professor of biological sciences, has discovered that receptor numbers are controlled by the brain's level of glutamate. But it is not the same glutamate that most neuroscientists think about -- the neurotransmitter that moves in message packets across the synapse. Instead, it is what Featherstone calls ambient extracellular glutamate, which just floats around the nervous system and has generally been ignored because no one knew where it came from or what it was doing.

For years, scientists failed to identify glutamate as a key neurotransmitter precisely because there was so much of it.

"It made no sense," said Featherstone. "People figured you couldn't use glutamate to send messages because there was too much glutamate background noise in the brain. It turns out that this background noise plays an important part in regulating information transfer."

Featherstone and his lab team found that glia cells are the source of the excess ambient glutamate. Along with neurons, these poorly understood "support" cells fill the brain.

The team discovered proteins in fruit fly glia cells that regulate the amount of ambient glutamate in the brain. Called xCT transporter proteins, they pump glutamate out of glia cells.

"Whe
'"/>

Contact: Paul Francuch
francuch@uic.edu
312-996-3457
University of Illinois at Chicago
2-Jan-2007


Page: 1 2

Related biology news :

1. Native fruits bear sweet antioxidants
2. Super fruit fly may lead to healthier humans
3. Do fruit flies have free will?
4. Berkeley Lab Life Sciences division awarded NIH grants for fruit fly, nematode studies
5. Similar brain chemicals influence aggression in fruit flies and humans
6. Researcher focuses on pros, cons of antioxidants from fruits and vegetables
7. Neighbors gone, fruits gone, species gone
8. A frenzy of fruit fly methods featured in Cold Spring Harbor Protocols
9. Why migrate? Its not for the fruit
10. Fatal attraction: Elephants and marula fruit
11. Researchers find link between food odors and lifespan in fruit flies

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/18/2020)... ... July 17, 2020 , ... Commercial launch readiness is a ... to discover a COVID cure or vaccine, the global economic downturn will only increase ... is not going away and capturing full value from every product launch is critical. ...
(Date:7/2/2020)... ... July 02, 2020 , ... ... a publication detailing the use of its revolutionary NEXTGENPCR endpoint thermocycler to ... in 16 minutes. The article, titled "Ultra-fast one-step RT-PCR protocol for the ...
(Date:6/25/2020)... , ... June 24, 2020 , ... ... enterprise software and software-driven clinical data services that accelerate drug development, is collaborating ... selinexor, an XPO1 inhibitor, in hospitalized patients with severe COVID-19. This is the ...
Breaking Biology News(10 mins):
(Date:8/12/2020)... ... August 11, 2020 , ... ... making available for free its new white paper – Simulated Transport Methodologies. ... into today’s biologics licensing application (BLA). In response, Modality Solutions shares an ...
(Date:7/31/2020)... SCOTTSDALE, Ariz. (PRWEB) , ... July 29, 2020 , ... ... cell joint injections for only $3950. With 50 million stem cells total, patients may ... well stem cell therapy works for arthritic joints (BMC Musculoskelet Disord. 2016). At R3 ...
(Date:7/31/2020)... ... July 29, 2020 , ... eSource has long been touted as ... cover the history of eSource, the reasons it did not take off as quickly ... site source, the industry is moving towards capturing data electronically for clinical trials and ...
(Date:7/18/2020)... ... ... “We are thrilled to deliver this new technology to the industry” said Matt Hundt, ... market and we were pleased that the IFT jury recognized that.” reFRESH™ couples the ... natural way to extend the shelf life and improve the safety of perishable foods ...
Breaking Biology Technology:
Cached News: