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Blood test for colon cancer risk to be goal of Hopkins project

orm a potential research subject," says Holly Taylor, M.P.H., Ph.D., an assistant professor of health policy and management and the Johns Hopkins Bloomberg School of Public Health and research director at Hopkins' Phoebe R. Berman Bioethics Institute. "We're going to try something new and see if we can facilitate understanding."

For this part of their project, the researchers will measure participants' understanding of the research, the blood test under study and the test's results to see whether an enhanced consent process is better than standard practice. The researchers also will explore how a positive test results affects participants' preventive health behavior.

Heading the project is Andrew Feinberg of Johns Hopkins. Other key investigators are Marcia Cruz-Correa of the University of Puerto Rico; Frank Giardiello, Elizabeth Platz, Christine Iacobuzio-Donahue and Hengmi Cui of Johns Hopkins; and Ben Wilfond on the National Human Genome Research Institute. Also collaborating on the project are Edward Giovannucci and Walter Willett of the Harvard School of Public Health.

(Data note: According to the National Cancer Institute, approximately 2.3 percent of women of Ashkenazi Jewish descent have troublesome forms of the BRCA1 and/or BRCA2 genes, a rate five times higher than the general population. http://cis.nci.nih.gov/fact/3_62.htm)


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Contact: Joanna Downer
jdowner1@jhmi.edu
410-614-5105
Johns Hopkins Medical Institutions
9-Sep-2005


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