Body's biological clock found to affect cardiac rhythm patterns in heal...( ound to have the greatest incidence of ...)

ound to have the greatest incidence of cardiac incidents, the team found the value was 1.2, edging toward the value linked with congestive heart failure. The team likewise found strong circadian rhythms whether data were considered only from the awake period or only from the sleep period.

"We are tempted to speculate that if the same circadian effect occurs in people with diseased hearts, then this may contribute to the day/night pattern of cardiac events," says BWH's Shea. "But this was only a study on healthy subjects, and, therefore, we are a long way from making clinical recommendations. Further studies could, however, provide insight to the underlying cause of the disease -- and to therapies that might work better by being timed to the specific phases of the body clock."

Brigham and Women's Hospital is a 735-bed nonprofit teaching affiliate of Harvard Medical School and a founding member of Partners HealthCare System, an integrated health care delivery network. Internationally recognized as a leading academic health care institution, BWH is committed to excellence in patient care, medical research, and the training and education of health care professionals.

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Contact: Ann Marie Menting
amenting@bu.edu
617-358-1240
Boston University
20-Dec-2004

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