HOME >> BIOLOGY >> NEWS
Bones hold the key to blood renewal

Though we think of them as solid and permanent, our bones are actually constantly being rebuilt throughout our lives. A team of scientists at the Weizmann Institute of Science has now revealed how cells that work at remodeling the bones play a direct part in the ongoing renewal of another system the blood. Their findings, which may lead to future improvements in bone marrow transplantation and a better understanding of diseases involving bone or blood renewal, were published in the June issue of Nature Medicine.

Bones are really two systems in one. The cavities inside bones are filled with spongy bone marrow, in which stem cells divide and their daughter cells differentiate into all kinds of blood cells, including large numbers of immune cells for the body's defense. The hematopoietic (literally, blood-creating) stem cells, which can give rise to any kind of blood cell, reside in special 'stem cell niches' nestled in the bones' inner walls. Inside these sheltered nurseries, the stem cells remain undifferentiated; with the help of other nearby cells, they hang on to their juvenile qualities. Only when they leave the niches do they morph into specialized blood cells, possibly becoming immune cells for fighting infection or cells for blood clotting and healing after injury. They can even respond to calls for help from organs such as the liver, migrating through the bloodstream to assist in repairing damage.

The inner walls of the bones are also sites of intensive reconstruction. While one type of cell, the osteoblast, is busy building bone, its partner, the osteoclast, breaks it down and reassimilates the material. Osteoclasts are formed when several cells (which themselves originate from hematopoietic stem cells) fuse together at a signal from the osteoblasts, and the two work together in a sort of 'urban renewal' scheme to keep the bones healthy and strong.

The Weizmann Institute team headed by Prof. Tsvee Lapidot of the Immunology'"/>

Contact: Jennifer Manning
jennifer@acwis.org
212-895-7952
American Committee for the Weizmann Institute of Science
19-Jun-2006


Page: 1 2 3

Related biology news :

1. Bones in motion: Brown scientists to create new 3-D X-ray system
2. Bones at the nanoscale
3. Bones from blood: Scientists aim to break new ground on fractures
4. High blood pressure, low energy -- a recipe for heart failure
5. Brain blood flow gives clues to treating depression
6. Study finds gender differences in renal and other genes contributing to blood pressure
7. Study suggests estrogen deficiency can lead to obesity-induced high blood pressure after menopause
8. Research aims to identify markers for menopausal women at risk for deadly blood clot
9. Teamwork between 2 key proteins necessary for normal development and regulation of red blood cells
10. A low expression of MX2 gene exists in the white blood cells of narcoleptics
11. How a pain in the neck could be bad for your blood pressure

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/19/2017)... The global military biometrics market ... by the presence of several large global players. The ... major players - 3M Cogent, NEC Corporation, M2SYS Technology, ... 61% of the global military biometric market in 2016. ... military biometrics market boast global presence, which has catapulted ...
(Date:4/17/2017)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... its 2016 Annual Report on Form 10-K on Thursday April 13, ... ... the Investor Relations section of the Company,s website at http://www.nxt-id.com ... http://www.sec.gov . 2016 Year Highlights: ...
(Date:4/13/2017)... April 13, 2017 According to a new market ... Identity Analytics, Identity Administration, and Authorization), Service, Authentication Type, Deployment Mode, Vertical, ... Market is expected to grow from USD 14.30 Billion in 2017 to ... of 17.3%. ... MarketsandMarkets Logo ...
Breaking Biology News(10 mins):
(Date:8/11/2017)... ... August 11, 2017 , ... ... and, in particular, more natural alternatives to synthetic ingredients,” said Matt Hundt, President ... Wave, with the established manufacturing presence and know-how of Biorigin will allow us ...
(Date:8/10/2017)... ... August 09, 2017 , ... ... in the clinic is here. The team at Capricor Therapeutics, Inc. utilized a ... for clinical studies. , Dr. Travis Antes, head of analytical development at ...
(Date:8/10/2017)... , ... August 09, 2017 , ... ... four international biomedical optics laboratories — the Wellman Center for Photomedicine, the Manstein ... Center Lübeck and the Beckman Laser Institute at University of California, Irvine — ...
(Date:8/10/2017)... Coral Springs, FL (PRWEB) , ... August 10, ... ... today announced that the stock market news outlet had initiated coverage on Next ... the rapidly growing and underserved consumer markets geared toward those that cannot engage ...
Breaking Biology Technology:
Cached News: