HOME >> BIOLOGY >> NEWS
Breakthrough: Structure of membrane protein described by Hebrew University, German researchers

Jerusalem --- The structure of the membrane protein NhaA has been revealed by researchers at the Hebrew University of Jerusalem and the Max Planck Institute of Germany.

Membrane protein research is at the forefront of modern biological study, with great potential consequences for development of new medicinal treatments and genetic engineering of plants.

The research on NhaA has been carried out by Etana Padan, the Adelina and Massimo DellaPergola Professor of Life Sciences, with Dr. Rimon Avraham, both of the Silberman Institute of Life Sciences at the Hebrew University, and Prof. Hartmut Michel, Nobel prize winner for chemistry in 1988, of the Max Planck for biophysics in Frankfurt, Germany. Their work, described in a recent edition of the journal Nature, was supported by a grant from the German-Israel Binational Science Foundation;

Proteins such as NhaA are found in the membranes of every living cell, from bacteria and up to humans. Until now, the structure of fewer than 50 cell membrane proteins have been discovered, as opposed to 30,000 soluble proteins.

"The location of the proteins in the cell membranes presents tremendous difficulties in research," said Prof. Padan. "Unlike the majority of those proteins which are soluble in water, the membrane proteins are soluble only in fats or in the presence of detergents."

The cell membrane is the crossroads of busy, two-way "traffic" through which materials and impulses travel into and out of the cell. The fatty cell membrane is impenetrable to most of these materials and signals; and it is therefore the proteins within the membranes that are responsible for the communication between the cell and its environment. Indeed, more than 60 percent of the medicines in use today are directed at the cell membrane proteins. Since the cell membrane proteins are exposed, in part, to areas extending outside the cells, the medicines are able to reach them without entering the cell itself.
'"/>

Contact: Jerry Barach
jerryb@savion.huji.ac.il
972-2-588-2904
The Hebrew University of Jerusalem
4-Aug-2005


Page: 1 2

Related biology news :

1. Breakthrough: Scientists create worlds tiniest organic particles
2. International Conference on Modern Bamboo Structures Oct. 11-17
3. Structure of iron regulatory protein-RNA complex solved
4. Self-assembling nano-ice discovered at UNL -- Structure resembles DNA
5. Structure of enzyme offers treatment clues for diabetes, Alzheimers
6. Structure determined for key molecular complex involved in long-term gene storage
7. Structure of key enzyme in plague bacterium found
8. Structure determined for p53 tumor suppressor protein as bound to DNA for anti-cancer activity
9. Structures of marine toxins provide insight into their effectiveness as cancer drugs
10. Structure-building cell signals also may influence learning, memory
11. Structure of new DNA enzyme family member found

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/5/2020)... ... 05, 2020 , ... Regenative Labs has received approval from the Centers for ... them the first Wharton’s jelly allografts to be assigned a Q code and be ... the first Wharton’s jelly allograft product to be recognized as a 361 HCT/P by ...
(Date:7/18/2020)... ... July 16, 2020 , ... ... effectiveness of the Invictus Medical Neoasis™ active noise control device to attenuate typical ... that the Neoasis™ device attenuated the alarm sounds from patient monitors, ventilators and ...
(Date:7/2/2020)... ... 01, 2020 , ... AltruBio Inc. http://www.altrubio.com , a ... for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGVHD), at European Hematology Association ... of the Fred Hutchinson Cancer Research Center, this single-arm, open-label Phase 1 single ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... 29, 2020 , ... Anomet Products has introduced new custom ... use with CRM, neurostimulation, vascular, and related devices. , Anomet Medical Clad ... performance, and cost criteria; especially where solid wire is limited. Typical configurations for ...
(Date:7/31/2020)... MIAMI (PRWEB) , ... July 29, 2020 , ... ... nearly 200 of the top radiation centers in 16 countries, has reached its ... years, SDX® is now in routine use at top universities including University of ...
(Date:7/18/2020)... (PRWEB) , ... July 16, 2020 , ... After research ... The completion of a great surgery is only the beginning of a successful study, ... research community. , Join Brad Gien, Global Head of Surgery from Envigo ...
(Date:7/18/2020)... ... July 17, 2020 , ... ... the life sciences and food industries, is pleased to announce that Charles Galea ... – Business Development. , Charles is an accomplished and results-driven sales executive with ...
Breaking Biology Technology:
Cached News: