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Breast implants not associated with cancer risk, study reports

Having breast implants is not associated with an increased risk of cancer overall, a new study reports in the April 19 issue of the Journal of the National Cancer Institute. Implants were associated with a decrease in breast cancer risk and an increased lung cancer risk, but these results likely reflect the lifestyles and smoking habits of the women in the study rather than an effect of the implants themselves, the authors conclude.

Past reports have examined the association between cosmetic breast implants and cancer risk, particularly breast cancer risk, but no consistent associations have been found. However, few studies have examined this association after more than 15 years.

Joseph K. McLaughlin, Ph.D., of the International Epidemiology Institute in Rockville, Md., and Vanderbilt-Ingram Cancer Center in Nashville, and colleagues examined the incidence of cancer in a nationwide cohort of 3486 Swedish women who underwent cosmetic surgery for breast implants between 1965 and 1993 and were followed until the end of 2002. Data was obtained from the Swedish Cancer Registry, which reports on cancer occurrence for the entire country. The average follow-up time was 18.4 years. The study is the longest follow-up study on cosmetic breast implants and risk of cancer incidence to date.

The authors identified 180 cancers in women with breast implants, fewer than the 193.1 predicted to occur in this population. Cosmetic implants were not associated with an increased risk of cancer overall. Women with implants had an increased incidence of lung cancer (20 cases observed, 9.1 cases expected) and a decreased incidence of breast cancer (53 cases observed, 71.9 cases expected) compared with the general population.

The authors suggest the higher incidence of lung cancer may be due to the high rates of smoking in Swedish women with cosmetic breast implants. Lower breast cancer incidence could be explained by the lower body mass index, highe
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Contact: Ariel Whitworth
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
18-Apr-2006


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