HOME >> BIOLOGY >> NEWS
British blackcurrants beat Alzheimer's

Compounds in blackcurrants could prevent Alzheimer's disease and the characteristics of British berries suggest they do it best, writes Jennifer Rohn in Chemistry & Industry magazine.

New research led by Dilip Ghosh of the Horticulture and Food Research Institute in New Zealand, shows that compounds in blackcurrants have a potent protective effect in cultured neuronal cells against the types of stress caused by dopamine and amyloid-b, a peptide associated with Alzheimer's disease.

'These compounds also work in hippocampal cells taken straight from the brain,' researcher James Joseph of Tufts University told Chemistry & Industry. Joseph says that the effect will likely be reproduced in the human body and that blackcurrants could help prevent or significantly delay the onset of Alzheimer's.

Blackcurrants and boysenberries, more common in the US, both contain anthocyanins and polyphenolics. British blackcurrants are bred to be darker, which means they have more anthocyanins and are likely to be more potent.

Compounds from these berries are already known to act as antioxidants, but a role in neuroprotection has not been demonstrated previously, according to the researchers.

The mechanism of action is unclear. But James said: 'We have evidence that the compounds protect against Alzheimer's by influencing the early gene expression in learning and memory, which influences cell signaling pathways that help neuronal cells communicate with each other.'

Dilip's team recently demonstrated the potent protective effect of blackcurrant compounds on cultured human promyeloyte and neuroblastoma cells assaulted by hydrogen peroxide (JSFA doi: 10.1002/jsfa.0247).


'"/>

Contact: Amy Molnar
amolnar@wiley.com
201-748-8844
John Wiley & Sons, Inc.
23-Jan-2006


Page: 1

Related biology news :

1. British cattle give TB to badgers, finds UC Davis expert
2. Poll reveals half British public support nuclear future
3. Eruption update: Island in British Overseas Territory is growing in size
4. Oil spills and climate change double the mortality rate of British seabirds
5. Big ears for British wheat
6. UCLA physiologist elected to prestigious British Royal Society
7. British academics to benefit from worlds first national text mining service
8. Johns Hopkins team wins British biotech business plan competition
9. Super blackcurrants with boosted vitamin C
10. Gilbert Foundation and American Fed for Aging Research award grants on Alzheimers disease
11. Link identified between Alzheimers disease and glaucoma

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/6/2019)... FRANCISCO (PRWEB) , ... February 04, 2019 , ... ... of a new Explorer™ story which provides insights to help individuals understand how ... to decreased cardiovascular wellness. , After individuals eat foods that contain choline ...
(Date:2/2/2019)... ... February 01, 2019 , ... uBiome, ... Testing Laboratories by A2LA, which establishes requirements for medical laboratories to demonstrate competence ... is already CLIA-licensed as well as College of American Pathologists (CAP)-accredited, a designation ...
(Date:1/24/2019)... ... 23, 2019 , ... rHEALTH LLC, an innovative digital health ... the United States Patent and Trademark Office (USPTO) for U.S. Patent Application No. ... This application covers the addition of a length scale to hydrogel microparticles. ...
Breaking Biology News(10 mins):
(Date:1/15/2019)... ... 15, 2019 , ... Personalized treatment plans may extend life expectancy for early-stage ... new study published in the journal Radiology. , Kidney, or renal, tumors are ... surgical procedure in which the tumor and part of the kidney are removed. However, ...
(Date:1/11/2019)... ... 11, 2019 , ... Drawing on over 22 years of software development expertise, ... EST will explore some of the key lessons that have driven customer satisfaction with ... multiple vendors, and find out how to ensure that you continue to be able ...
(Date:1/10/2019)... (PRWEB) , ... January 08, 2019 , ... VGI Medical ... has become a leader in bringing innovation to the market including VerteLoc, CerLoc, SiJoin ... the facet joint by utilizing a unique patented dual geometric design to limit motion ...
(Date:1/7/2019)... ... 07, 2019 , ... Kainos Medicine Inc. today announced that ... code-named "KM-819." KM-819 is an orally active small molecule that is a ... , This Phase 1 randomized, double-blind, placebo-controlled dose-escalation study was to evaluate ...
Breaking Biology Technology:
Cached News: