HOME >> BIOLOGY >> NEWS
Cancer tip -- Nanoparticles can damage DNA, increase cancer risk

LOS ANGELES -- Tissue studies indicate that nanoparticles, engineered materials about a billionth of a meter in size, could damage DNA and lead to cancer, according to research presented at the 2007 Annual Meeting of the American Association for Cancer Research.

Nanoparticles are small enough to penetrate cell membranes and defenses, yet they are large enough to cause trouble by interfering with normal cell processes, researchers at the University of Massachusetts say. Such nanoparticles are currently in use in electronics, cosmetics, and chemical manufacturing, among others industries. Because of their extremely small size, they can be difficult to isolate from the larger environment, as they are much too small for removal by conventional filtering techniques.

When nanoparticles find their way into cancer cells, they can wreak havoc, according to Sara Pacheco, an undergraduate researcher at the University of Massachusetts. Yet very little is known about how they behave in the environment or how they interact with and affect humans.

"Unfortunately, only a very small portion of research on nanoparticles is focused on health and safety risks, or on threats to the environment," Pacheco said. "I am concerned because so many new nanoparticles are being developed and there is little regulation on their manufacture, use and disposal."

Pacheco and her colleagues looked at how two different types of nanoparticles could cause DNA damage in the MCF-7 line of breast cancer cells.

She and her team examined the genotoxicity of silica and C60 fullerene nanoparticle suspensions using the alkaline single-cell gel electrophoresis assay (Comet assay) to quantify breaks in single and double stranded DNA. The team chose these particular nanoparticle types because they are commonly used commercially in electronics, textiles and sporting goods and easy to work with in the laboratory setting.

"We observed both dose-
'"/>

Contact: Staci Vernick Goldberg
goldberg@aacr.org
267-646-0616
American Association for Cancer Research
17-Apr-2007


Page: 1 2

Related biology news :

1. Journalists can register now for ECCO 14 -- the European Cancer Conference
2. Cancer cures could work for canines and humans
3. The Cancer Genome Atlas awards funds for technology development
4. Cancer research specialist and HSPH professor awarded Medal of Honor from WHO cancer agency
5. Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
6. Cancer stem cells can go it alone
7. Cancer drug enhances long-term memory
8. Cancer cells reprogram energy needs to grow and spread, study suggests
9. Cancer scientists create human leukemia process to map how disease begins, progresses
10. Other highlights from the April 18 Journal of the National Cancer Institute
11. American Association for Cancer Research provides support for promising cancer scientists

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/26/2020)... LUXEMBOURG (PRWEB) , ... August ... ... Luxembourg-based clinical-stage biotechnology company developing novel pharmaceuticals targeting mitochondria, in partnership with ... of enrolment in its pivotal U.S. Phase 3 VISTA-2 study of SkQ1 ...
(Date:8/21/2020)... Calif. (PRWEB) , ... August 19, 2020 , ... ... both Salimetrics LLC and SalivaBio LLC, businesses dedicated to Salivary Bioscience for more ... of the recently published book by Springer, " Salivary Bioscience: Foundations of Interdisciplinary ...
(Date:8/7/2020)... ... August 06, 2020 , ... Alucio™, ... to announce that Eric Chen and Jessica Wong have joined the company’s leadership ... Strategy, respectively. , Eric Chen heads development efforts for Alucio’s flagship product, Beacon, ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... (PRWEB) , ... July 29, 2020 , ... eSource has ... inefficiencies. This webinar will cover the history of eSource, the reasons it did not ... EMR/EHR to wearables, to site source, the industry is moving towards capturing data electronically ...
(Date:7/22/2020)... ... , ... Join experts from Reed Tech , Gary Saner, Sr. Manager, ... hour live webinar on Thursday, August 13, 2020 at 11am EDT (4pm ... devices. Specifically, for medical devices, the NMPA has departments dealing with medical device registration ...
(Date:7/18/2020)... ... July 16, 2020 , ... ... aid in the early detection and prevention of high-burden diseases, and Centric Consulting, ... hospitals and healthcare organizations to utilize existing data in order to identify and ...
(Date:7/10/2020)... ... July 09, 2020 , ... ... announced today that Massachusetts Institute of Technology (MIT) has expanded the company’s ... allows PathSensors to move into the point-of-care diagnostic market, focusing initially on ...
Breaking Biology Technology:
Cached News: