HOME >> BIOLOGY >> NEWS
Canine cancer vaccine program shows early promise

MADISON - It wasn't publicized, other than by word of mouth, and still the University of Wisconsin-Madison School of Veterinary Medicine was overwhelmed with requests. Since 1998, the school's oncology department has been producing an anti-cancer vaccine for dogs diagnosed with melanoma. Though it is still an experimental treatment, dog owners from all over the nation have wanted to participate in the study, on the remote chance that this would help their pet.

After promising results from work done in collaboration with cancer specialists from Arizona, California, and Michigan, the school has hired a full-time technician to produce the existing vaccine. The vaccine being used now has undergone a few modifications designed to increase its anti-cancer activity. "Not all dogs with melanoma respond to this treatment," cautions Ilene Kurzman, a researcher in the veterinary medical school's oncology section. "But those that do seem to do quite well."

She would like to continue working on the vaccine in the hope that this innovative anti-cancer strategy will translate into similar novel treatments in people with cancer.

Melanoma, the equivalent of one form of skin cancer in humans, is very aggressive in dogs. It usually manifests itself in or around the mouth or toes. Despite conventional treatment, 75 percent of dogs with oral melanoma will die within one year.

But about 40 percent of dogs with a melanoma tumor present responded to a vaccine created from actual melanoma tumor cells. In about 12.5 percent of the treated dogs, the tumor completely disappeared. While the current results are promising, funding limitations reduce the program's ability to take the next step in improving the vaccine and increasing the percentage of animals that respond, Kurzman says.

According to Kurzman, the vaccine is created from dog melanoma cells that are grown in the laboratory. The cells are treated so they can no longer divide and cause a
'"/>

Contact: Tania Banak
banakt@svm.vetmed.wisc.edu
608-263-6914
University of Wisconsin-Madison
26-Jan-2006


Page: 1 2

Related biology news :

1. Protein chatter linked to cancer activation
2. Newly created cancer stem cells could aid breast cancer research
3. Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
4. ESF EURYI award winner aims to stop cancer cells reading their own DNA
5. No evidence that widely prescribed statins protect against prostate cancer
6. A study by the MUHC and McGill University opens a new door to understanding cancer
7. New study suggests Concord grape juice may provide protection against breast cancer
8. New test improves detection of liver cancer
9. High-intensity ultrasound may launch attack on cancer, wherever it lurks
10. Unknotting DNA clue to cancer syndrome
11. Biologists at Tufts University discover 1 reason why chromosomes break, often leading to cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/19/2017)... New York , April 19, 2017 ... competitive, as its vendor landscape is marked by the ... the market is however held by five major players ... Safran. Together these companies accounted for nearly 61% of ... of the leading companies in the global military biometrics ...
(Date:4/13/2017)... According to a new market research report "Consumer IAM Market by Solution ... Authentication Type, Deployment Mode, Vertical, and Region - Global Forecast to 2022", ... 14.30 Billion in 2017 to USD 31.75 Billion by 2022, at a ... ... MarketsandMarkets Logo ...
(Date:4/11/2017)... , April 11, 2017 NXT-ID, ... security technology company, announces the appointment of independent Directors Mr. ... to its Board of Directors, furthering the company,s corporate ... ... NXT-ID, we look forward to their guidance and benefiting from ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... ... advancing targeted antibody-drug conjugate (ADC) therapeutics, today confirmed licensing rights that give ... Liposomal Nanoparticle), a technology developed in collaboration with Children’s Hospital Los Angeles ...
(Date:10/10/2017)... ... October 10, 2017 , ... Dr. Bob Harman, founder and CEO of ... Club. The event entitled “Stem Cells and Their Regenerative Powers,” was ... Dr. Harman, DVM, MPVM was joined by two human doctors: Peter B. Hanson, M.D., ...
(Date:10/10/2017)... 2017 SomaGenics announced the receipt of a ... RealSeq®-SC (Single Cell), expected to be the first commercially ... microRNAs) from single cells using NGS methods. The NIH,s ... accelerate development of approaches to analyze the heterogeneity of ... techniques for measuring levels of mRNAs in individual cells ...
(Date:10/10/2017)... ... October 10, 2017 , ... The ... prestigious awards honoring scientists who have made outstanding contributions to analytical ... during Pittcon 2018, the world’s leading conference and exposition for laboratory science, which ...
Breaking Biology Technology:
Cached News: