HOME >> BIOLOGY >> NEWS
Carbon monoxide inhibitor controls traumatic bleeding, Tulane University researchers show

SAN FRANCISCO A chemical that blocks carbon monoxide (CO) has been used for the first time to arrest traumatic bleeding in rats, according to a Tulane University research team.

The study of CO in the tissues -- including its role in diabetes, cardiac dysfunction, hypertension and asthma -- has become the subject of increasing interest for researchers. However, this is the first time scientists are looking at its role in soft tissue trauma, said lead researcher Mary E. McCarty, who presented the study at an APS session at Experimental Biology 2006.

Small amounts of CO exist in the tissues, the result of the breakdown of a blood component known as heme. Carbon monoxide helps control blood pressure by dilating blood vessels, McCarty said. Her team reasoned that blocking the dilating action of CO would cause injured blood vessels to constrict, limiting bleeding and maintaining adequate blood pressure.

The research is still a long way from use in humans. But if successful, this new line of inquiry could eventually help stanch massive bleeding in instances of soft tissue trauma and help reduce the need for blood transfusions of patients facing lengthy surgery, among other uses.

McCarty is one of 12 finalists for a David S. Bruce Undergraduate Research Award from The American Physiological Society (APS). She will present the study at an APS-sponsored session at Experimental Biology 2006.

*Paper presentation: "Inhibitors of endogenously-formed CO arrest bleeding and confer protection in a model of severe hepatic injury," 12:45 p.m.-3 p.m. Wednesday, April 5, Shock, 903.16/Board #D16, Convention Center, Exhibit Hall D. The poster is on view 7:30 a.m. 3:30 p.m. Research was by Mary E. McCarty, Fruzsina K. Johnson, Christine S. Lin, Robert A. Johnson, Department of Physiology, Tulane University Health Sciences Center, New Orleans, and William Durante, Department of Medicine, Baylor College of Medicine, Houston.

In addition, McC
'"/>

Contact: Christine Guilfoy
cguilfoy@the-aps.org
301-634-7253
American Physiological Society
6-Apr-2006


Page: 1 2 3

Related biology news :

1. Tough tubes -- Carbon nanotubes endure heavy wear and tear
2. Carbon dioxide and the ocean
3. Carbon monoxide protects mice from multiple sclerosis
4. Carbon monoxide protects lung cells against oxygen-induced damage
5. On the cutting edge: Carbon nanotube cutlery
6. Carbon capture, water filtration, other boreal forest ecoservices worth estimated $250 billion/year
7. Carbon monoxide may help prevent debilitating pregnancy condition
8. Carbon cycle was already disrupted millions of years ago
9. Carbon nanotube absorption measured in worms, cancer cells
10. Carbon nanotubes that detect disease-causing mutations developed by Pitt researcher
11. Carbon nanoparticles stimulate blood clotting, researchers report

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/7/2020)... ... January 06, 2020 , ... Myant Inc. , the pioneers ... Vegas) to bring to life its vision of a world where textile-based interfaces knitted ... the AI-powered digital sphere, and the physical IoT-enabled environment. The experience at Myant’s booth ...
(Date:12/30/2019)... SAN DIEGO (PRWEB) , ... December 30, 2019 , ... ... cooking events company has seen its highest sales in 2019, having hosted a multitude ... and Illumina, have all visited the company’s La Jolla-based venue, and the company has ...
(Date:12/18/2019)... ... December 17, 2019 , ... EconoFact, a non-profit media initiative ... Fletcher School, Tufts University, is pleased to announce a collaboration with Macmillan Learning ... using Macmillan Learning’s acclaimed series of economics textbooks. , Under the agreement, Macmillan ...
Breaking Biology News(10 mins):
(Date:1/8/2020)... ... 08, 2020 , ... Anomet Products has introduced ... use in harsh environments inside or outside of the human body. , ... alloys to achieve specific properties such as corrosion-resistance, biocompatibility, or operation at temperatures ...
(Date:1/7/2020)... ... 07, 2020 , ... Vuja De Sciences (“Vuja De”), a biotechnology startup dedicated ... appointments of Chand Khanna, DVM, PhD, DACVIM (Onc), and Dr. Lee Helman, MD, to ... are delighted to welcome Chand and Lee as new directors. They will be of ...
(Date:1/7/2020)... ... January 06, 2020 , ... ABCT ... emerging biosciences ventures invited to participate in the annual program. Twelve ventures will ... plans and a professional network. All startups will receive an entrepreneur coach, access ...
(Date:12/30/2019)... ... December 30, 2019 , ... Leak ... instruments for the Pharmaceutical, Biotechnology, Medical Device and Food Packaging Industries is pleased ... 11 compliant software program specific to the custom-built helium leak testing systems it ...
Breaking Biology Technology:
Cached News: