HOME >> BIOLOGY >> NEWS
Carbon nanoparticles stimulate blood clotting, researchers report

HOUSTON (Oct. 21, 2005) --Carbon nanoparticles both those unleashed in the air by engine exhaust and the engineered structures thought to have great potential in medical applications promote blood-clotting, scientists report in an upcoming edition of the British Journal of Pharmacology.

Researchers from The University of Texas Health Science Center at Houston and Ohio University examined the impact of various forms of carbon nanoparticles in a laboratory experiment on human platelets blood's principal clotting element and in a model of carotid artery thrombosis, or blockage, using anesthetized rats.

"We found that some carbon nanoparticles activate human platelets and stimulate them to aggregate, or clump together. We also demonstrate that the same nanoparticles stimulated blockage of the carotid artery in the rat model," said research team leader Marek Radomski, M.D., Ph.D., of the Center for Vascular Biology at the Brown Foundation Institute of Molecular Medicine (IMM) at the UT Health Science Center.

C60, a spherical carbon molecule also known as a fullerene or "bucky ball," was the exception, showing no effect on human platelet aggregation and very little effect on rat thrombosis.

"This research is not a case against nanotechnology. It's difficult to overestimate the importance of this amazing technology's ability to transform medicine. But it's good to assess the risk of a new technology in advance. This is a case for moving ahead in a cautious and informed way," said Radomski, who also is a professor of integrative biology and pharmacology at the UT Medical School at Houston.

Nanoparticles so tiny that they are measured in billionths of a meter pass easily through the lungs and into the bloodstream, Radomski said, where they can interact with platelets. They also tend to aggregate on their own, a property that could also enhance blood clotting.

"Medical evidence has been accumulating mainly from ep
'"/>

Contact: Scott Merville
scott.merville@uth.tmc.edu
713-500-3042
University of Texas Health Science Center at Houston
21-Oct-2005


Page: 1 2 3

Related biology news :

1. Tough tubes -- Carbon nanotubes endure heavy wear and tear
2. Carbon dioxide and the ocean
3. Carbon monoxide protects mice from multiple sclerosis
4. Carbon monoxide protects lung cells against oxygen-induced damage
5. On the cutting edge: Carbon nanotube cutlery
6. Carbon capture, water filtration, other boreal forest ecoservices worth estimated $250 billion/year
7. Carbon monoxide may help prevent debilitating pregnancy condition
8. Carbon cycle was already disrupted millions of years ago
9. Carbon monoxide inhibitor controls traumatic bleeding, Tulane University researchers show
10. Carbon nanotube absorption measured in worms, cancer cells
11. Carbon nanotubes that detect disease-causing mutations developed by Pitt researcher

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/11/2020)... , ... March 11, 2020 , ... ... wireless sensing, today announced smart human body temperature infrared touch-free monitoring product family, ... thermal meter WxS x800-IRTM, supporting flexible wireless uplink for cloud connectivity such as ...
(Date:3/9/2020)... ... March 09, 2020 , ... Application transformation ... as enterprises sought to achieve competitive advantage by transforming their core applications, ... transformation efforts delivered the intended consequences. , Application transformation refers to the ...
(Date:3/5/2020)... ... March 05, 2020 , ... ... of its Scientific Advisory Board (SAB) comprised of the industry’s key opinion ... cell therapy centers, and private industry. Cytonus is a leading cell-based platform ...
Breaking Biology News(10 mins):
(Date:4/1/2020)... ... 2020 , ... Bedoukian Research, Inc. (BRI) and ... Agreement that builds on each company’s expertise in developing efficient routes to synthesize ... of high-quality insect pheromones as well as flavors and fragrances. P2 has developed ...
(Date:3/19/2020)... ... March 18, 2020 , ... Family ... signals to provide rapid insight into their perceptions of events. Imagine if a ... other. What if they could measure the level of engagement of each individual ...
(Date:3/10/2020)... ... March 10, 2020 , ... ... chain biopharmaceutical engineering firm, is pleased to announce the addition of Carson ... medical device qualification and validation in the biopharmaceutical cold chain. He provides ...
(Date:3/3/2020)... ... March 03, 2020 , ... Frictionless ... and medical device industries, was recognized by INC. 5,000 on an annual list ... to note industry leaders greatly impacting their spheres of influence and experiencing considerable ...
Breaking Biology Technology:
Cached News: