HOME >> BIOLOGY >> NEWS
Carbon nanoparticles stimulate blood clotting, researchers report

HOUSTON (Oct. 21, 2005) --Carbon nanoparticles both those unleashed in the air by engine exhaust and the engineered structures thought to have great potential in medical applications promote blood-clotting, scientists report in an upcoming edition of the British Journal of Pharmacology.

Researchers from The University of Texas Health Science Center at Houston and Ohio University examined the impact of various forms of carbon nanoparticles in a laboratory experiment on human platelets blood's principal clotting element and in a model of carotid artery thrombosis, or blockage, using anesthetized rats.

"We found that some carbon nanoparticles activate human platelets and stimulate them to aggregate, or clump together. We also demonstrate that the same nanoparticles stimulated blockage of the carotid artery in the rat model," said research team leader Marek Radomski, M.D., Ph.D., of the Center for Vascular Biology at the Brown Foundation Institute of Molecular Medicine (IMM) at the UT Health Science Center.

C60, a spherical carbon molecule also known as a fullerene or "bucky ball," was the exception, showing no effect on human platelet aggregation and very little effect on rat thrombosis.

"This research is not a case against nanotechnology. It's difficult to overestimate the importance of this amazing technology's ability to transform medicine. But it's good to assess the risk of a new technology in advance. This is a case for moving ahead in a cautious and informed way," said Radomski, who also is a professor of integrative biology and pharmacology at the UT Medical School at Houston.

Nanoparticles so tiny that they are measured in billionths of a meter pass easily through the lungs and into the bloodstream, Radomski said, where they can interact with platelets. They also tend to aggregate on their own, a property that could also enhance blood clotting.

"Medical evidence has been accumulating mainly from ep
'"/>

Contact: Scott Merville
scott.merville@uth.tmc.edu
713-500-3042
University of Texas Health Science Center at Houston
21-Oct-2005


Page: 1 2 3

Related biology news :

1. Tough tubes -- Carbon nanotubes endure heavy wear and tear
2. Carbon dioxide and the ocean
3. Carbon monoxide protects mice from multiple sclerosis
4. Carbon monoxide protects lung cells against oxygen-induced damage
5. On the cutting edge: Carbon nanotube cutlery
6. Carbon capture, water filtration, other boreal forest ecoservices worth estimated $250 billion/year
7. Carbon monoxide may help prevent debilitating pregnancy condition
8. Carbon cycle was already disrupted millions of years ago
9. Carbon monoxide inhibitor controls traumatic bleeding, Tulane University researchers show
10. Carbon nanotube absorption measured in worms, cancer cells
11. Carbon nanotubes that detect disease-causing mutations developed by Pitt researcher

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/20/2017)... DAL ) customers now can use fingerprints instead of their boarding ... ... biometrics to board aircraft at Reagan Washington National Airport ... Delta,s biometric boarding pass experience that launched in May at the ... to allow eligible Delta SkyMiles Members who are enrolled in CLEAR to ...
(Date:6/14/2017)... IBM ) is introducing several innovative partner startups at VivaTech ... startups and global businesses, taking place in Paris ... will showcase the solutions they have built with IBM Watson ... France is one of the most dynamic ... in the number of startups created between 2012 and 2015*, ...
(Date:5/16/2017)... , May 16, 2017   Bridge Patient ... organizations, and MD EMR Systems , an ... partner for GE, have established a partnership to ... product and the GE Centricity™ products, including Centricity ... These new integrations will allow ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... 11, 2017 , ... Proscia Inc ., a data ... titled, “Pathology is going digital. Is your lab ready?” with Dr. Nicolas Cacciabeve, ... and how Proscia improves lab economics and realizes an increase in diagnostic confidence.* ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... implantation and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... and maternal age to IVF success. , After comparing the results from the ...
(Date:10/10/2017)... , ... October 10, 2017 , ... ... Center’s FirstHand program has won a US2020 STEM Mentoring Award. Representatives of the ... for Excellence in Volunteer Experience from US2020. , US2020’s mission is to change ...
(Date:10/10/2017)... ... 10, 2017 , ... USDM Life Sciences , the ... sciences and healthcare industries, announces a presentation by Subbu Viswanathan and Jennifer Jaye ... GxP Validation for Agile Cloud Platforms,” will present a revolutionary approach to achieving ...
Breaking Biology Technology:
Cached News: