HOME >> BIOLOGY >> NEWS
Carnegie Mellon scientist plays key role in unveiling sea urchin genome

t in their last common ancestor and, conversely, what genes have appeared more recently in the two lineages since they diverged many hundreds of million years ago.

"Having the sea urchin genome is almost an epiphany. I can see the genes, and it's very exciting," added Ettensohn, who has been studying the sea urchin as a model of development for more than 25 years. Specifically, he focuses on the vast network of proteins needed for these animals to form skeletons through biomineralization.

"If we understand how sea urchins build their skeletons, we can learn more about how we build our skeletons," Ettensohn said. "Additionally, understanding how natural systems build skeletons can help us mimic that in the design of materials to treat bone disease and injury in humans."

As part of the Sea Urchin Genome Sequencing Consortium, Ettensohn contributed 51,000 cDNAs -- about one-third of the total genomic material critical for the assembly of the genome and for the accurate prediction of where genes lie within the DNA sequence.

The Ettensohn lab was also one of 15 labs to annotate sets of genes that comprise the sea urchin genome. Initially, computers assembled the genome sequence and predicted the sea urchin genes. These predictions were then verified by scientists in the lab. Ettensohn annotated the genes involved in biomineralization, the process by which sea urchins form their embryonic skeletons. His work resulted in a comprehensive catalog of all the genes that are actually being used by the embryonic cells responsible for building the skeleton, including when and where the genes are expressed in the embryo.

In the sea urchin embryo, specialized cells produce proteins that mix with mineral crystals, thereby regulating the growth and shape of the emerging skeleton, just as in humans. But having the sea urchin genome has revealed a provocative discovery: many of the biomineralization proteins, especially those that control
'"/>

Contact: Lauren Ward
wardle@andrew.cmu.edu
412-268-7761
Carnegie Mellon University
9-Nov-2006


Page: 1 2 3

Related biology news :

1. Carnegie Mellons Peter Adams receives EPA research grant
2. Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily
3. Carnegie Mellons David Sholl identifies new materials
4. Carnegie Mellon University scientists identify genes activated during learning and memory
5. Carnegie Mellon University research shows how sensory-deprived brain compensates
6. Carnegie Mellon researchers urge regulators to rethink strategies for soot emission
7. Carnegie Mellon researcher proposes development of artificial cells to fight disease
8. Carnegie Mellon engineers devise new process to improve energy efficiency of ethanol production
9. DNA gets new twist: Carnegie Mellon scientists develop unique DNA nanotags
10. Carnegie Mellons Granger Morgan pens op-ed
11. Carnegie Mellon study reveals that odor discrimination is linked to the timing at which neurons fire

Post Your Comments:
(Date:7/7/2015)... VIEW, Calif. , July 7, 2015 /PRNewswire/ ... biometrics market, Frost & Sullivan recognizes Credence ID, ... Sullivan Entrepreneurial Company of the Year Award. ... suite to aid in its mission of offering ... under-recognized populations globally. As Credence ID was formed ...
(Date:6/30/2015)... -- To bolster its efforts and commitment to fighting cyber ... addition of two new team members. ... David Raviv will act as head of strategic alliances. ... providing the most secure solutions for the enterprise market. ... Technologies, a provider of security and management products, which was ...
(Date:6/25/2015)... , June 25, 2015  Imagine a tool ... toward a healthier, happier life. That,s exactly what USANA,s ... to do. The cutting-edge, portable health program provides a ... solutions to help improve your lifestyle and nutrition. ... dinner and gala Wednesday night, USANA,s THA was honored ...
Breaking Biology News(10 mins):Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 2Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 5HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 2HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 3@USANAinc's Personalized Nutrition Program Wins Industry Innovation Award 2
(Date:7/29/2015)... 29, 2015 /PRNewswire/ - BioAmber Inc. (NYSE: BIOA ) ... Chief Financial Officer has resigned.  The Company has hired ... who retired in December 2014, as full time interim ... successor.     Andy Ashworth began his ... a smooth transition.  Andy was the Company,s CFO from ...
(Date:7/29/2015)... ... July 29, 2015 , ... Brady (NYSE:BRC), a ... Label Guide . To align chemical container labeling with OSHA’s updated Hazard Communication ... label components, an example of an accurate label, and pictogram uses and meanings. ...
(Date:7/29/2015)... ... July 29, 2015 , ... The third Medical Innovation Impact ... products , in particular, drug/device combinations. The current system received a score of 0 ... for Patient Centered Innovation (iPCI) of Fairleigh Dickinson University’s ( FDU ) Rothman ...
(Date:7/29/2015)... ... July 29, 2015 , ... ... introduces CHRONO NIGHT Express Contouring Bi-Gel, a nighttime-specific product that targets fat cells ... sugars that are able to enter fat cells, inhibiting the formation of new ...
Breaking Biology Technology:BioAmber Announces Change in Chief Financial Officer 2BioAmber Announces Change in Chief Financial Officer 3Brady Announces a New GHS Label Guide 2Third Medical Innovation Impact Index Issued by Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) 2Third Medical Innovation Impact Index Issued by Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) 3Phytocéane introduces CHRONO NIGHT Express Contouring Bi-Gel 2Phytocéane introduces CHRONO NIGHT Express Contouring Bi-Gel 3
Cached News: