HOME >> BIOLOGY >> NEWS
Carnegie Mellon scientist plays key role in unveiling sea urchin genome

t in their last common ancestor and, conversely, what genes have appeared more recently in the two lineages since they diverged many hundreds of million years ago.

"Having the sea urchin genome is almost an epiphany. I can see the genes, and it's very exciting," added Ettensohn, who has been studying the sea urchin as a model of development for more than 25 years. Specifically, he focuses on the vast network of proteins needed for these animals to form skeletons through biomineralization.

"If we understand how sea urchins build their skeletons, we can learn more about how we build our skeletons," Ettensohn said. "Additionally, understanding how natural systems build skeletons can help us mimic that in the design of materials to treat bone disease and injury in humans."

As part of the Sea Urchin Genome Sequencing Consortium, Ettensohn contributed 51,000 cDNAs -- about one-third of the total genomic material critical for the assembly of the genome and for the accurate prediction of where genes lie within the DNA sequence.

The Ettensohn lab was also one of 15 labs to annotate sets of genes that comprise the sea urchin genome. Initially, computers assembled the genome sequence and predicted the sea urchin genes. These predictions were then verified by scientists in the lab. Ettensohn annotated the genes involved in biomineralization, the process by which sea urchins form their embryonic skeletons. His work resulted in a comprehensive catalog of all the genes that are actually being used by the embryonic cells responsible for building the skeleton, including when and where the genes are expressed in the embryo.

In the sea urchin embryo, specialized cells produce proteins that mix with mineral crystals, thereby regulating the growth and shape of the emerging skeleton, just as in humans. But having the sea urchin genome has revealed a provocative discovery: many of the biomineralization proteins, especially those that control
'"/>

Contact: Lauren Ward
wardle@andrew.cmu.edu
412-268-7761
Carnegie Mellon University
9-Nov-2006


Page: 1 2 3

Related biology news :

1. Carnegie Mellons Peter Adams receives EPA research grant
2. Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily
3. Carnegie Mellons David Sholl identifies new materials
4. Carnegie Mellon University scientists identify genes activated during learning and memory
5. Carnegie Mellon University research shows how sensory-deprived brain compensates
6. Carnegie Mellon researchers urge regulators to rethink strategies for soot emission
7. Carnegie Mellon researcher proposes development of artificial cells to fight disease
8. Carnegie Mellon engineers devise new process to improve energy efficiency of ethanol production
9. DNA gets new twist: Carnegie Mellon scientists develop unique DNA nanotags
10. Carnegie Mellons Granger Morgan pens op-ed
11. Carnegie Mellon study reveals that odor discrimination is linked to the timing at which neurons fire

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/10/2019)... (PRWEB) , ... January 09, 2019 , ... Dr. Beanlands ... Heart Institute in Ottawa, Ontario, Canada. He is also Director of its National ... of Medicine, in the Department of Radiology, and in the Department of Cellular and ...
(Date:1/8/2019)... ... January 07, 2019 , ... Join industry experts Julie Peacock, Client Services at ... on Thursday, January 17, 2019 at 1pm EST. , This webinar will ... clinical trial process. Featured speakers will also present a case study of a leading ...
(Date:1/7/2019)... (PRWEB) , ... January 07, 2019 , ... ... (RWD) and Artificial Intelligence solutions for precision health in oncology and other key ... J.P Morgan’s exclusive meeting of investors, entrepreneurs and executives spanning the entire healthcare ...
Breaking Biology News(10 mins):
(Date:12/13/2018)... FRANKLIN, Wis. (PRWEB) , ... December 13, 2018 ... ... HACCP scope which now includes food (human) ingredient. This has been part of ... Having a Food Safety Plan and certification creates custom fermentation opportunities for MDG ...
(Date:12/5/2018)... ... December 05, 2018 , ... Leading authority on how to ... guide with his “The Referral Playbook: How to Increase Sales with Proven Networking ... proceeds will go to the Alzheimer’s Foundation of America (AFA). , Itzkowich is ...
(Date:12/5/2018)... ... December 05, 2018 , ... STRmix™ – sophisticated forensic software capable of resolving ... used to convict a Wyoming man of third-degree sexual assault, a felony punishable by ... test for DNA on the couch cushions on which the sexual assault was alleged ...
(Date:11/29/2018)... , ... November 29, 2018 , ... RAGS, today announced ... by Kickstart Seed Fund, with participation from existing investor and board member Jeremy Andrus, ... Smith of Cotopaxi. The additional funding will enable the company to accelerate its growth ...
Breaking Biology Technology:
Cached News: