Case Western Reserve University School of Medicine gets $4 million to make 'smart nanoparticles'

The School of Medicine received $4 million in funding from the State of Ohio's Third Frontier Initiative for Targeted Nanoparticles for Imaging and Therapeutics (TNIP), which will support the development and commercialization of sub-atomic particles for the early detection of breast cancers and new therapies for hemophilia. Case Western Reserve University will work in collaboration with local companies Cleveland NanoCrystals, Copernicus Therapeutics, Inc., iMedd, Inc., and Ricera Biosciences, Inc. Principal investigator for TNIP is Pamela B. Davis, M.D., Ph.D., professor of pediatrics and senior associate dean for research at the School of Medicine.

Davis said the plan is to create smart nanoparticles that can accomplish several things:

  • Light up on imaging only at sites of disease,
  • Deliver photoactivated molecules to cancerous lesions so as to kill the tumors, not the healthy tissue around them,
  • Deliver payloads of corrective genes to treat genetic disorders, and payloads of inhibitory nucleic acids to suppress viral infections or cancers,
  • Deliver effective drugs that are otherwise too toxic or too insoluble to be used in humans.

    "There is a full plan to develop not only the science but also to bring the drugs to market so that people can have access to them and benefit," said Davis. "Diseases that are targeted are hemophilia, viral infections, and cancer."

    The grant was announced by Ohio's Lt. Gov. Bruce Johnson as part of a $75 million grant package handed out throughout the state. More than half the funding will go to Northeast Ohio.

    In addition to the nanoparticles grant, the Cleveland Clinic Foundation, Case Western Reserve University and collaborating businesses received two grants for the creation of the Atrial Fibrillation Innovation Center. A Wright Center of Innovation (WCI) grant, worth $15 million, and a Biomedical Research and Technology Transfer Partnership Program (BRTT),

  • Contact: George Stamatis
    Case Western Reserve University

    Page: 1 2 3 4

    Related biology news :

    1. Study finds Western-style meat-sweet diet increases risk of breast cancer in postmenopausal women
    2. Case Western Reserve University School of Medicine researchers awarded $27M for TB research
    3. Case Western researcher, international team call for better global warming forecasting
    4. WHSRN awarded major grant to foster shorebird conservation throughout the Western Hemisphere
    5. Case Western Reserve University biologists suspect lightning fires help preserve oak forests
    6. Case Western Reserve University licenses methoxyamine to Tracon
    7. Case Western Reserve University chemist takes on HIV-1 virus with $1M support from NIH
    8. Case Western Reserve University paleontologist discovers South American mammal fossils
    9. Case Western Reserve University researchers find protein associated with brain cell death
    10. In Western bluebird as well as human families, accumulated wealth encourages stability
    11. ASU students host first annual Western Regional Bioethics Conference

    Post Your Comments:

    (Date:10/29/2015)... , Oct. 29, 2015  Rubicon Genomics, ... for U.S. distribution of its DNA library preparation ... and Rubicon,s new ThruPLEX Plasma-seq kit. ThruPLEX Plasma-seq ... the preparation of NGS libraries for liquid biopsies--the ... diagnostic and prognostic applications in cancer and other ...
    (Date:10/27/2015)... -- Munich, Germany , October ... automatically maps data from mobile eye tracking videos created ... that they can be quantitatively analyzed with SMI,s analysis ... , October 28-29, 2015. SMI,s Automated Semantic Gaze ... tracking videos created with SMI,s Eye Tracking Glasses ...
    (Date:10/23/2015)... , Oct. 23, 2015 Research and ... the "Global Voice Recognition Biometrics Market 2015-2019" ... --> The global voice recognition biometrics ... 2014-2019. --> --> ... has been prepared based on an in-depth market analysis ...
    Breaking Biology News(10 mins):
    (Date:11/25/2015)... CITY , Nov. 25, 2015 /PRNewswire/ - Aeterna ... affirms that its business and prospects remain fundamentally ... , Zoptrex™ (zoptarelin doxorubicin) recently received DSMB recommendation ... to completion following review of the final interim ... Phase 2 Primary Endpoint in men with heavily ...
    (Date:11/25/2015)... ... November 25, 2015 , ... Jessica Richman and Zachary Apte, ... their initial angel funding process. Now, they are paying it forward to other ... stage investments in the microbiome space. In this, they join other successful ...
    (Date:11/24/2015)... Therapeutics, Inc. (NASDAQ: HALO ) will be presenting at the ... on Wednesday, December 2 at 9:30 a.m. ET/6:30 a.m. PT . ... a corporate overview. th Annual Oppenheimer Healthcare Conference ... a.m. PT . Jim Mazzola , vice president of ... --> th Annual Oppenheimer Healthcare Conference in ...
    (Date:11/24/2015)... , Nov. 24, 2015 /PRNewswire/ - Aeterna Zentaris ... of IIROC on behalf of the Toronto Stock Exchange, ... release there are no corporate developments that would cause ... --> --> About Aeterna ... www.aezsinc.com . --> Aeterna Zentaris is a ...
    Breaking Biology Technology:
    Cached News: