HOME >> BIOLOGY >> NEWS
Case Western Reserve University School of Medicine gets $4 million to make 'smart nanoparticles'

The School of Medicine received $4 million in funding from the State of Ohio's Third Frontier Initiative for Targeted Nanoparticles for Imaging and Therapeutics (TNIP), which will support the development and commercialization of sub-atomic particles for the early detection of breast cancers and new therapies for hemophilia. Case Western Reserve University will work in collaboration with local companies Cleveland NanoCrystals, Copernicus Therapeutics, Inc., iMedd, Inc., and Ricera Biosciences, Inc. Principal investigator for TNIP is Pamela B. Davis, M.D., Ph.D., professor of pediatrics and senior associate dean for research at the School of Medicine.

Davis said the plan is to create smart nanoparticles that can accomplish several things:

  • Light up on imaging only at sites of disease,
  • Deliver photoactivated molecules to cancerous lesions so as to kill the tumors, not the healthy tissue around them,
  • Deliver payloads of corrective genes to treat genetic disorders, and payloads of inhibitory nucleic acids to suppress viral infections or cancers,
  • Deliver effective drugs that are otherwise too toxic or too insoluble to be used in humans.

    "There is a full plan to develop not only the science but also to bring the drugs to market so that people can have access to them and benefit," said Davis. "Diseases that are targeted are hemophilia, viral infections, and cancer."

    The grant was announced by Ohio's Lt. Gov. Bruce Johnson as part of a $75 million grant package handed out throughout the state. More than half the funding will go to Northeast Ohio.

    In addition to the nanoparticles grant, the Cleveland Clinic Foundation, Case Western Reserve University and collaborating businesses received two grants for the creation of the Atrial Fibrillation Innovation Center. A Wright Center of Innovation (WCI) grant, worth $15 million, and a Biomedical Research and Technology Transfer Partnership Program (BRTT),
    '"/>



  • Contact: George Stamatis
    George.Stamatis@case.edu
    216-368-3635
    Case Western Reserve University
    11-May-2005


    Page: 1 2 3 4

    Related biology news :

    1. Study finds Western-style meat-sweet diet increases risk of breast cancer in postmenopausal women
    2. Case Western Reserve University School of Medicine researchers awarded $27M for TB research
    3. Case Western researcher, international team call for better global warming forecasting
    4. WHSRN awarded major grant to foster shorebird conservation throughout the Western Hemisphere
    5. Case Western Reserve University biologists suspect lightning fires help preserve oak forests
    6. Case Western Reserve University licenses methoxyamine to Tracon
    7. Case Western Reserve University chemist takes on HIV-1 virus with $1M support from NIH
    8. Case Western Reserve University paleontologist discovers South American mammal fossils
    9. Case Western Reserve University researchers find protein associated with brain cell death
    10. In Western bluebird as well as human families, accumulated wealth encourages stability
    11. ASU students host first annual Western Regional Bioethics Conference

    Post Your Comments:
    (Date:10/22/2014)... -- Leading identity analyst firm Acuity Market Intelligence forecasts that ... will have a chip-based National eID card, including near-complete ... Asia , with its vast population, is ... 60% of all National eID cards issued between 2014 ... National eID Industry Report: 2014 Edition" — ...
    (Date:10/18/2014)... Berlin, 19th October 2014 Psychological stress and stress-related ... for aging-related diseases, but the molecular mechanisms ... mechanisms may contribute to the development of ... treatments for these devastating diseases. This work ... Neuropsychopharmacology congress in Berlin., Now an international ...
    (Date:10/17/2014)... – Accurate knowledge regarding Ebola is critical and pertinent ... of hazardous global outbreak and epidemic. The Journal, ... a special issue, Ebola Virus and Public Health, to ... knowledge in this critical societal moment. , On ... Ebola for Clinicians . The primer was prepared by ...
    Breaking Biology News(10 mins):Half the World's Population Will Have Chip-Based National Electronic Identity (eID) Cards by 2018 2Researchers find why depression and aging linked to increased disease risk 2
    (Date:10/25/2014)... Oramed Pharmaceuticals Inc. (NASDAQCM: ORMP) ... the development of oral drug delivery systems, announced today ... present at FireRock Capital,s Micro-Cap Conference. ... Tuesday, October 28, 2014 ,Time: 9:15am EST ,Location: The ... , About The FireRock Conference  ...
    (Date:10/25/2014)... , Oct 24, 2014 Research ... "Epigenetics Market by Product , Research Area & ... report to their offering. In this ... basis of products, research areas, and end users. The ... report are enzymes, instruments & consumables, kits, and reagents. ...
    (Date:10/22/2014)... BOSTON , Oct. 22, 2014  Actavis plc ... pharmaceutical company, and Rhythm, a biopharmaceutical company, today announced ... acquire Rhythm,s wholly owned subsidiary, Rhythm Health, Inc., which ... the treatment of diabetic gastroparesis and other GI functional ... Phase 2 trial of relamorelin for the treatment of ...
    (Date:10/22/2014)... Massachusetts (PRWEB) October 22, 2014 ... announced the release of a new infographic, Understanding ... to create a beautifully designed, easy to follow informative ... transmission, areas of outbreak, symptoms and prevention. , "As ... discovered that the 2014 Ebola outbreak represents not only ...
    Breaking Biology Technology:Oramed to Present at the FireRock Annual Micro-Cap Conference 2Oramed to Present at the FireRock Annual Micro-Cap Conference 3Global Epigenetics (VLA, WBA, NBA, RTA, Rotary-Wing Aircraft) Market - Forecast to 2019 2Global Epigenetics (VLA, WBA, NBA, RTA, Rotary-Wing Aircraft) Market - Forecast to 2019 3Actavis Signs Option to Acquire Rhythm Subsidiary and its GI Development Product, Relamorelin 2Actavis Signs Option to Acquire Rhythm Subsidiary and its GI Development Product, Relamorelin 3Actavis Signs Option to Acquire Rhythm Subsidiary and its GI Development Product, Relamorelin 4Actavis Signs Option to Acquire Rhythm Subsidiary and its GI Development Product, Relamorelin 5Involution Studios' Ebola Infographic Provides Key Disease Information and Statistics at a Glance 2
    Cached News: