Case Western Reserve University School of Medicine gets $4 million to make 'smart nanoparticles'

The School of Medicine received $4 million in funding from the State of Ohio's Third Frontier Initiative for Targeted Nanoparticles for Imaging and Therapeutics (TNIP), which will support the development and commercialization of sub-atomic particles for the early detection of breast cancers and new therapies for hemophilia. Case Western Reserve University will work in collaboration with local companies Cleveland NanoCrystals, Copernicus Therapeutics, Inc., iMedd, Inc., and Ricera Biosciences, Inc. Principal investigator for TNIP is Pamela B. Davis, M.D., Ph.D., professor of pediatrics and senior associate dean for research at the School of Medicine.

Davis said the plan is to create smart nanoparticles that can accomplish several things:

  • Light up on imaging only at sites of disease,
  • Deliver photoactivated molecules to cancerous lesions so as to kill the tumors, not the healthy tissue around them,
  • Deliver payloads of corrective genes to treat genetic disorders, and payloads of inhibitory nucleic acids to suppress viral infections or cancers,
  • Deliver effective drugs that are otherwise too toxic or too insoluble to be used in humans.

    "There is a full plan to develop not only the science but also to bring the drugs to market so that people can have access to them and benefit," said Davis. "Diseases that are targeted are hemophilia, viral infections, and cancer."

    The grant was announced by Ohio's Lt. Gov. Bruce Johnson as part of a $75 million grant package handed out throughout the state. More than half the funding will go to Northeast Ohio.

    In addition to the nanoparticles grant, the Cleveland Clinic Foundation, Case Western Reserve University and collaborating businesses received two grants for the creation of the Atrial Fibrillation Innovation Center. A Wright Center of Innovation (WCI) grant, worth $15 million, and a Biomedical Research and Technology Transfer Partnership Program (BRTT),

  • Contact: George Stamatis
    Case Western Reserve University

    Page: 1 2 3 4

    Related biology news :

    1. Study finds Western-style meat-sweet diet increases risk of breast cancer in postmenopausal women
    2. Case Western Reserve University School of Medicine researchers awarded $27M for TB research
    3. Case Western researcher, international team call for better global warming forecasting
    4. WHSRN awarded major grant to foster shorebird conservation throughout the Western Hemisphere
    5. Case Western Reserve University biologists suspect lightning fires help preserve oak forests
    6. Case Western Reserve University licenses methoxyamine to Tracon
    7. Case Western Reserve University chemist takes on HIV-1 virus with $1M support from NIH
    8. Case Western Reserve University paleontologist discovers South American mammal fossils
    9. Case Western Reserve University researchers find protein associated with brain cell death
    10. In Western bluebird as well as human families, accumulated wealth encourages stability
    11. ASU students host first annual Western Regional Bioethics Conference

    Post Your Comments:

    (Date:6/30/2017)... Va. , June 30, 2017 ... leading developer and supplier of face and eye ... ATA Featured Product provider program. ... an innovative way to monitor a driver,s attentiveness ... greatly from being able to detect fatigue and ...
    (Date:5/16/2017)... 16, 2017  Veratad Technologies, LLC ( www.veratad.com ), ... and identity verification solutions, announced today they will participate ... May 15 thru May 17, 2017, in ... Trade Center. Identity impacts the lives ... today,s quickly evolving digital world, defining identity is critical ...
    (Date:4/19/2017)... New York , April 19, 2017 ... competitive, as its vendor landscape is marked by the ... the market is however held by five major players ... Safran. Together these companies accounted for nearly 61% of ... of the leading companies in the global military biometrics ...
    Breaking Biology News(10 mins):
    (Date:10/10/2017)... California (PRWEB) , ... October 10, 2017 , ... Dr. ... speaking at his local San Diego Rotary Club. The event entitled ... Diego, CA and had 300+ attendees. Dr. Harman, DVM, MPVM was joined by ...
    (Date:10/10/2017)... SomaGenics announced the receipt of a Phase ... (Single Cell), expected to be the first commercially available ... from single cells using NGS methods. The NIH,s recent ... development of approaches to analyze the heterogeneity of cell ... for measuring levels of mRNAs in individual cells have ...
    (Date:10/10/2017)... ... 2017 , ... The Pittcon Program Committee is pleased to ... who have made outstanding contributions to analytical chemistry and applied spectroscopy. Each award ... conference and exposition for laboratory science, which will be held February 26-March 1, ...
    (Date:10/9/2017)... ... 09, 2017 , ... The award-winning American Farmer television series will feature 3 ... airs Tuesdays at 8:30aET on RFD-TV. , With global population estimates nearing ten ... to continue to feed a growing nation. At the same time, many of our ...
    Breaking Biology Technology:
    Cached News: