HOME >> BIOLOGY >> NEWS
Cells selectively absorb short nanotubes

DNA-wrapped single-walled carbon nanotubes (SWCNTs) shorter than about 200 nanometers readily enter into human lung cells and so may pose an increased risk to health, according to scientists at the National Institute of Standards and Technology (NIST). The results of their laboratory studies appear in an upcoming issue of Advanced Materials.*

Eyed for uses ranging from electronic displays to fuel cells to water filtration, SWCNTs are tiny cylindersessentially single-sheet rolls of carbon atoms. They are many times stronger than steel and possess superlative thermal, optical and electronic properties, but safety and biocompatibility remain an open question.

"Published data citing in vitro (outside the body) toxicity are particularly inconsistent and widely disputed," writes biomaterials scientist Matthew Becker and his NIST colleagues. Public concerns surrounding the environmental, health and safety impacts of SWCNTs could derail efforts to fast track the development of nanotubes for advanced technology applications. A significant hurdle in outlining the parameters contributing to nanotube toxicity is to prepare well-defined and characterized nanotube samples, as they typically contain a distribution of lengths, diameters, twists and impurities.

The team chose to isolate the effects of nanotube length. They first adsorbed short DNA molecules onto the nanotubes because this renders them soluble in water and allows them to be sorted and separated by length. The researchers then exposed human lung fibroblasts to solutions containing unsorted nanotubes. Regardless of the concentration levels, the cells did not absorb between about one-fourth and one-third of the SWCNTs in the solutions. Further examination of the results revealed that only short nanotubes made it into the cellular interior.

In the next phase of the research, the team exposed the cells to sorted nanotubes of controlled length. They found that tubes longer than a
'"/>

Contact: Michael Baum
michael.baum@nist.gov
301-975-2763
National Institute of Standards and Technology (NIST)
30-Mar-2007


Page: 1 2

Related biology news :

1. Cells take risks with their identities
2. Cells re-energize to come back from the brink of death
3. Need oxygen? Cells know how to spend and save
4. Cells use noise to make cell-fate decisions
5. Cells in the lung clear the air to prevent lung damage
6. Cells passed from mother to child during pregnancy live on and make insulin
7. Cells, dyes and videotape: Online scientific methods journal incorporates multimedia
8. Cells use mix-and-match approach to tailor regulation of genes
9. Cells in mucus from lungs of high-risk patients can predict tumor development
10. Double-trouble: Cells with duplicate genomes can trigger tumors
11. Double trouble: Cells with duplicate genomes can trigger tumors

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/12/2020)... ... August 11, 2020 , ... ... in Princeton, NJ, have entered into license agreements with Housey Pharma’s HMI subsidiary ... Both Roche and J&J have annual Research and Development spending in excess of ...
(Date:8/3/2020)... ... , ... Accumen Inc. is helping healthcare get better, faster. ... to provide COVID-19 saliva testing kits nationally. , “Accumen has been partnering ... years. Early in the COVID-19 crisis, we identified supply chain gaps and began ...
(Date:7/18/2020)... ... July 17, 2020 , ... Commercial launch readiness is ... ability to discover a COVID cure or vaccine, the global economic downturn will only ... pressure is not going away and capturing full value from every product launch is ...
Breaking Biology News(10 mins):
(Date:7/22/2020)... (PRWEB) , ... July 22, 2020 , ... Join experts ... John Lorenc, Sr. Manager Regulatory Solutions, in a one hour live webinar ... the regulating body in China for drugs and medical devices. Specifically, for medical devices, ...
(Date:7/10/2020)... (PRWEB) , ... July 08, 2020 , ... ... services and products, announces a significant expansion of laboratory operations through its ... for agencies implementing testing programs. , Bode-CARES provides a turnkey ...
(Date:7/7/2020)... ... 2020 , ... Bio-IT World has announced the winners of ... University of Chicago, Massachusetts General Hospital, Mission: Cure, and the Pistoia Alliance were ... outstanding examples of how technology innovations and strategic initiatives can be powerful forces ...
(Date:6/28/2020)... ... June 25, 2020 , ... With the COVID-19 ... or drug treatment. In an effort to better understand the cellular responses to ... largest imaging dataset portraying therapeutic compound effects from over 1,600 approved and referenced ...
Breaking Biology Technology:
Cached News: