Cerebellum found to be important in cognition and behavior

Higher cognitive functions, like language and visual processing, have long been thought to reside primarily in the brain's cerebrum. But a body of research in premature infants at Children's Hospital Boston is documenting an important role for the cerebellum previously thought to be principally involved in motor coordination and shows that cerebellar injury can have far-reaching developmental consequences.

The latest study, in the October issue of Pediatrics, also demonstrates that the cerebrum and cerebellum are tightly interconnected. Sophisticated MRI imaging of 74 preterm infants' brains revealed that when there was injury to the cerebrum, the cerebellum failed to grow to a normal size. When the cerebral injury was confined to one side, it was the opposite cerebellar hemisphere that failed to grow normally. The reverse was also true: when injury occurred in one cerebellar hemisphere, the opposite cerebral hemisphere was smaller than normal.

"There seems to be an important developmental link between the cerebrum and the cerebellum," says Catherine Limperopoulos, PhD, in Children's Department of Neurology, the study's lead author. "We're finding that the two structures modulate each other's growth and development. The way the brain forms connections between structures may be as important as the injury itself."

As neuroimaging becomes more sophisticated, cerebellar injury is increasingly recognized as a complication of premature birth. Improved survival of fragile preemies, coupled with a surge in premature births, has left more and more families to deal with the damage to their babies' brains including cerebellar damage.

In March, Limperopoulos and colleagues published a study in Pediatrics showing that the cerebellum grows rapidly late in gestation much faster than the cerebral hemispheres and that premature birth arrests this surge in development. In another study, published in Pediatrics in September, they found that the

Contact: Aaron Patnode
Children's Hospital Boston

Page: 1 2 3

Related biology news :

1. Waters off Washington state only second place in world where glass sponge reefs found
2. First new multiple sclerosis gene found in 30 years
3. Obesity found to be a risk factor for multiple myeloma
4. Antibody-altering protein found in developing B cells
5. New use for a cell toxin found to inhibit survival proteins in cancer cells
6. New way to target and kill antibiotic-resistant bacteria found
7. Soil particles found to boost prions capacity to infect
8. Support for chromosomal theory of cancer found in cancers development of drug resistance
9. Massive herds of animals found to still exist in Southern Sudan
10. Origins of nervous system found in genes of sea sponge, report scientists at UC Santa Barbara
11. Origins of nervous system found in genes of sea sponge

Post Your Comments:

(Date:5/26/2020)... ... May 26, 2020 , ... ... today announced that Gritstone Oncology, Inc., a clinical-stage biotechnology company developing cancer ... and TCR-based therapeutics, has implemented Genedata Biologics ® within their R&D ...
(Date:5/21/2020)... ... ... Law Enforcement has always been a highly stressful career – serving to ... men and women put them constantly in harm’s way both from the criminal element ... had to face very high daily stress. Now, COVID-19 introduces another even greater degree ...
(Date:5/14/2020)... , ... May 14, 2020 , ... ... board for medical sales representatives, found the 2019 average medical sales rep total ... risk being shadowed by uncertainties amid the COVID-19 global crisis. , The MedReps ...
Breaking Biology News(10 mins):
(Date:4/7/2020)... ... April 06, 2020 , ... Red ... life sciences industry, has announced the release of at-home virtual learning resources for ... is the health and safety of our employees as we continue to implement ...
(Date:4/1/2020)... , ... March 30, 2020 , ... ... telehealth developer Reliant Immune Diagnostics (RID), formed earlier this year to bring telehealth ... by creating in-home tests for COVID-19. Company officials are currently?awaiting an Emergency Use ...
(Date:4/1/2020)... SALT LAKE CITY, and LA JOLLA, Calif. (PRWEB) , ... March ... ... and characterization tools, and La Jolla Institute for Immunology (LJI), announced today that they ... few days allowing CoVIC to move therapeutic candidates to the clinic as early as ...
(Date:3/27/2020)... ... March 25, 2020 , ... ... located centrally in the midwest for high-quality, quick-turn, board-certified reporting. In an ... motivated, independent, professional team that is focused on incredible quality, turnaround time ...
Breaking Biology Technology:
Cached News: