HOME >> BIOLOGY >> NEWS
Charting ever-changing genomes

La Jolla, CA -- Instead of immutable proprietary software, any species genetic information resembles open source code that is constantly tweaked and optimized to meet the users specific needs. But which parts of the code have withstood the test of time and which parts have undergone rapid evolutionary change has been difficult to assess.

An international collaboration by researchers at the Salk Institute for Biological Studies, the University of Chicago, and the Max-Planck Institute for Developmental Biology developed a simple method to comb whole genomes for all the software fixes and security patches accumulated over time. In a first trial run, the scientists catalogued the genetic variations in 23 strains of the mustard weed Arabidopsis thaliana that were collected from the wild all over the world.

Our study represents one of the first whole genome scans for levels and patterns of genetic variation within a species, says Joseph R. Ecker, Ph.D., professor in the Plant Biology Laboratory and director of the Salk Institute Genomic Analysis Laboratory, who led the current study published in last weeks online edition of the Proceedings of the National Academy of Science. It reveals the regions that are currently targeted by natural selection or have been so during the evolutionary past.

In an independent study the collaborators -- this time led by Detlef Weigel, Ph.D., director of the Max Planck Institute for Developmental Biology in Tbingen, Germany, and an adjunct professor at the Salk Institute -- went through the genomes of 20 different strains of Arabidopsis thaliana with an even finer-toothed comb, allowing them to determine the exact nature of the changes. The findings of the second study are published in the July 20 issue of the journal Science.

We found that one out of 10 genes is very different, says Weigel. This plasticity is truly surprising for a genome thats very streamlined and unlike bigger genomes doesnt con
'"/>

Contact: Gina Kirchweger
kirchweger@salk.edu
858-453-4100 x1340
Salk Institute
19-Jul-2007


Page: 1 2 3

Related biology news :

1. Charting the path of the deadly Ebola virus in central Africa
2. One species, many genomes
3. Despite their heft, many dinosaurs had surprisingly tiny genomes
4. 2,000 influenza virus genomes now completed and publicly accessible
5. DOE JGI releases IMG 2.0 with all genomes refreshed from RefSeq
6. Whats shaped like a pear and has two genomes? Check the pond
7. DOE JGI releases IMG 1.5 with curated archaeal genomes
8. Human and chimp genomes reveal new twist on origin of species
9. Bioportfolio: Life-long persistence of erythrovirus DNA genomes in human tissue
10. Sex, cleaner of genomes
11. Breaking the mold: Research teams sequence three fungus genomes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/12/2018)... ... September 10, 2018 , ... IONpathTM, ... of its new Multiplexed Ion Beam Imaging (MIBITM) technology was accepted by the ... will also be shared during a webinar presented by Dr. Mike Angelo on ...
(Date:9/7/2018)... ... 2018 , ... Sensors Midwest (#SensorsMW18), the event ... Expo & Conference , announces their partnership with Fraunhofer USA Center for Experimental ... Industrial IoT Certification Program. Taking place on October 17, 2018 at the Donald ...
(Date:8/31/2018)... MADISON, Wisc. (PRWEB) , ... August 30, 2018 ... ... to measure inhibitor residence times as a component of drug discovery programs. Longer-target ... deriving these residence times are low throughput, require expensive instrumentation, or require the ...
Breaking Biology News(10 mins):
(Date:8/17/2018)... (PRWEB) , ... August 16, 2018 , ... The opening ... Astro Pak acquired Chemko Technical Services in 2016. Chemko had a well established local ... on-site work at KSC on projects such as the ongoing work at the Mobile ...
(Date:8/17/2018)... ... August 16, 2018 , ... ... their results from the AmbryShare project were published today in JAMA Oncology, identifying ... largest exome study ever conducted. , Every year hereditary breast cancer affects more ...
(Date:8/14/2018)... ... ... Labconco Corporation manufactures laboratory equipment, specializing in ventilation enclosures ... other lab equipment, such as glassware washers and freeze dryers. Labconco has ISO ... and manufacturing. , Through this webinar, which is sponsored by Labconco ...
(Date:8/14/2018)... (PRWEB) , ... August 14, 2018 , ... ... further impetus at the 11th Congress of the Chinese Association of Orthopaedic Surgeons ... event, Fule Science & Technology Development , Beijing, and Invibio Biomaterial ...
Breaking Biology Technology:
Cached News: