HOME >> BIOLOGY >> NEWS
Charting ever-changing genomes

La Jolla, CA -- Instead of immutable proprietary software, any species genetic information resembles open source code that is constantly tweaked and optimized to meet the users specific needs. But which parts of the code have withstood the test of time and which parts have undergone rapid evolutionary change has been difficult to assess.

An international collaboration by researchers at the Salk Institute for Biological Studies, the University of Chicago, and the Max-Planck Institute for Developmental Biology developed a simple method to comb whole genomes for all the software fixes and security patches accumulated over time. In a first trial run, the scientists catalogued the genetic variations in 23 strains of the mustard weed Arabidopsis thaliana that were collected from the wild all over the world.

Our study represents one of the first whole genome scans for levels and patterns of genetic variation within a species, says Joseph R. Ecker, Ph.D., professor in the Plant Biology Laboratory and director of the Salk Institute Genomic Analysis Laboratory, who led the current study published in last weeks online edition of the Proceedings of the National Academy of Science. It reveals the regions that are currently targeted by natural selection or have been so during the evolutionary past.

In an independent study the collaborators -- this time led by Detlef Weigel, Ph.D., director of the Max Planck Institute for Developmental Biology in Tbingen, Germany, and an adjunct professor at the Salk Institute -- went through the genomes of 20 different strains of Arabidopsis thaliana with an even finer-toothed comb, allowing them to determine the exact nature of the changes. The findings of the second study are published in the July 20 issue of the journal Science.

We found that one out of 10 genes is very different, says Weigel. This plasticity is truly surprising for a genome thats very streamlined and unlike bigger genomes doesnt con
'"/>

Contact: Gina Kirchweger
kirchweger@salk.edu
858-453-4100 x1340
Salk Institute
19-Jul-2007


Page: 1 2 3

Related biology news :

1. Charting the path of the deadly Ebola virus in central Africa
2. One species, many genomes
3. Despite their heft, many dinosaurs had surprisingly tiny genomes
4. 2,000 influenza virus genomes now completed and publicly accessible
5. DOE JGI releases IMG 2.0 with all genomes refreshed from RefSeq
6. Whats shaped like a pear and has two genomes? Check the pond
7. DOE JGI releases IMG 1.5 with curated archaeal genomes
8. Human and chimp genomes reveal new twist on origin of species
9. Bioportfolio: Life-long persistence of erythrovirus DNA genomes in human tissue
10. Sex, cleaner of genomes
11. Breaking the mold: Research teams sequence three fungus genomes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... (NYSE: IBM ) is introducing several innovative partner startups ... collaboration between startups and global businesses, taking place in ... nine startups will showcase the solutions they have built with ... France is one of the ... percent increase in the number of startups created between 2012 ...
(Date:5/16/2017)... 16, 2017   Bridge Patient Portal , ... MD EMR Systems , an electronic medical ... GE, have established a partnership to build an ... the GE Centricity™ products, including Centricity Practice Solution ... These new integrations will allow healthcare delivery ...
(Date:4/19/2017)... New York , April 19, 2017 ... competitive, as its vendor landscape is marked by the ... the market is however held by five major players ... Safran. Together these companies accounted for nearly 61% of ... of the leading companies in the global military biometrics ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... platform specifically designed for life science researchers to analyze and interpret datasets, ... Franklin, who made a major contribution to the discovery of the double-helix ...
(Date:10/11/2017)... ... ... Personal eye wash is a basic first aid supply for any work environment, but most ... you rinse first if a dangerous substance enters both eyes? It’s one less decision, and ... unique dual eye piece. , “Whether its dirt and debris, or an acid or alkali, ...
(Date:10/11/2017)... , Oct. 11, 2017  VMS BioMarketing, a leading ... a nationwide oncology Clinical Nurse Educator (CNE) network, which will ... need for communication among health care professionals to enhance the ... nurses, office staff, and other health care professionals to help ... breast cancer. ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... implantation and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... and maternal age to IVF success. , After comparing the results from the ...
Breaking Biology Technology:
Cached News: