HOME >> BIOLOGY >> NEWS
Children's Hospital and Research Center-Oakland presents a new maternal diet study

November 13, 2006 - Oakland, CA A new study by scientists at Children's Hospital Oakland Research Institute (CHORI) is the first to show that a mother's diet during pregnancy influences the health of her grandchildren by changing the behavior of a specific gene. The study was conducted using mice of an unique strain called "viable yellow agouti" also known as Avy in scientific terms. These mice possess a gene that influences the color of their coats as well as their tendency to become obese and develop diabetes and cancer. The new research shows that the diet consumed by a pregnant Avy mouse affects the health of not only her pups, but also their pups her grandchildren.

The study will be published in the November issue of the Proceedings of the National Academy of Sciences and was conducted by CHORI Scientist David Martin, M.D., and Assistant Scientist Kenneth Beckman, Ph.D., in collaboration with Drs. Jennifer Cropley and Catherine Suter from the Victor Chang Heart Institute in Sydney, Australia. In their experiments, the scientists fed some Avy mice a standard lab diet based on common foods consumed by humans. Other mice were fed this same diet supplemented with common nutritional supplements including folate, choline, betaine, vitamin B12, zinc and methionine.

The supplements were fed to the mice for a week during mid-pregnancy. The offspring were examined for their coat color, and female offspring were themselves mated again (without a supplemented diet) to produce a third generation of "grandchildren." The results showed that the supplements changed the behavior of the agouti gene in the first generation of pups, shifting their coats towards a brown color, and had the same effect on pups born in the next generation to mice that were not exposed to the supplemented diet.

"Although researchers have long known that there is a connection between a mother's diet and her children's health this is the first case in which the relationsh
'"/>

Contact: Diana Yee
dyee@mail.cho.org
510-428-3120
Children's Hospital & Research Center at Oakland
13-Nov-2006


Page: 1 2

Related biology news :

1. Doernbecher Childrens Hospital scientist earns coveted Javits award
2. NIH selects Childrens Hospital as Center of Excellence to train future generations of scientists
3. Childrens Hospital Oakland, Calif.s new iron regulation discovery
4. Childrens Hospital researcher leads multipronged attack on infant leukemia
5. Childrens Hospital Oaklands new maternal diet study
6. Childrens Hospital Boston presents at the 2006 American Academy of Pediatrics National Conference
7. Genetic research at Childrens Hospital of Pittsburgh reinforces theory of evolution
8. Childrens Hospital Boston presents at the 2006 Pediatric Academic Societies annual meeting
9. UCLA engineering and Mattel Childrens Hospital collaborate to develop childrens heart valve
10. Childrens Hospital Oakland scientist awarded seat on national scientific review board
11. Research center for National Childrens Study to be based in Queens

Post Your Comments:
(Date:10/25/2014)...   MedNet Solutions , a global life sciences ... pleased to announce the 2014 iMedNet User ... held in Bloomington, Minnesota on ... attendance and promises to be informative, productive and enjoyable ... the meeting is iMedNet™ EDC , ...
(Date:10/25/2014)... , Oct. 22, 2014 This report ... a relatively new space in heavy pursuit of research ... unique to miRNAs compared to other RNA components. miRNA,s ... it a novel candidate for use as a biomarker ... of miRNA-based microarrays and diagnostics for the advancement in ...
(Date:10/25/2014)... -- A recent report, "Genetic Testing Market Outlook 2018", ... genetic testing market. A comprehensive introduction of gene-based tests, ... report. On account of our analysis of the past ... challenges; forecast for genetic testing has been drawn, according ... a CAGR of around 9% during 2013-2018. Our ...
Breaking Biology News(10 mins):MedNet Solutions To Host Third Annual iMedNet User Group Meeting 2MicroRNA: An Insight to miRNA-based microarrays, diagnostics and therapeutics Overview, Cambridge Healthtech Advisors 2Genetic Testing Market Outlook 2018 2
(Date:10/25/2014)... NEW YORK , Oct. 24, ... formerly Access Pharmaceuticals, Inc. (ACCP), a biopharmaceutical company ... has implemented a 1-for-50 reverse split of its ... on Friday, October 24, 2014. PlasmaTech,s common stock ... CUSIP number 72754H109 and temporary ticker symbol "ACCPD". ...
(Date:10/25/2014)... 24, 2014 ... has announced the addition of the  "The ... Other 2-D Nanomaterials "  report to their ... ,CNTs and graphene are the strongest, lightest ... with a performance-per-weight greater than any other ...
(Date:10/22/2014)... The Americas Inorganic Refrigerants Market ... in Americas with analysis and forecast of revenue. ... Inorganic Refrigerants Market report, to get an idea ... a glimpse of the segmentation in the Americas ... tables and figures. , http://www.micromarketmonitor.com/market/americas-inorganic-refrigerants-4191654241.html ...
(Date:10/22/2014)... NJ (PRWEB) October 22, 2014 ... and services – has been working with a team ... and New Haven Farms Community Farming Collaborative to provide ... ePRO solution. The study, which started in May, ... program that provides participants weekly exposure to and participation ...
Breaking Biology Technology:PlasmaTech Biopharmaceuticals, Inc. Announces Reverse Stock Split, Ticker Change and Launches New Corporate Website 2The Global Market for Carbon Nanotubes, Graphene and Other 2-D Nanomaterials 2The Global Market for Carbon Nanotubes, Graphene and Other 2-D Nanomaterials 3The Global Market for Carbon Nanotubes, Graphene and Other 2-D Nanomaterials 4The Americas Inorganic Refrigerants Market is estimated to grow to $71.6 million by 2018 - New Report by MicroMarket Monitor 2The Americas Inorganic Refrigerants Market is estimated to grow to $71.6 million by 2018 - New Report by MicroMarket Monitor 3myPROpad™ Topic of Panel Discussion at the Yale Food Systems Symposium 2myPROpad™ Topic of Panel Discussion at the Yale Food Systems Symposium 3
Cached News: