The Latest Biology News And Medical NewsBiology News 2Health News 2Biology News 3Health News 3
HOME >> BIOLOGY >> NEWS
Children's Hospital researcher leads multipronged attack on infant leukemia

While survival rates for childhood leukemia have dramatically improved over the past 30 years, infants with this blood cancer continue to face difficult odds. Infant leukemia resists treatments such as chemotherapy and stem cell transplants that may be effective in older children, and infants are especially vulnerable to treatment side effects.

A new research effort led by a leukemia expert at The Children's Hospital of Philadelphia seeks to harness in-depth understanding of genes and molecular pathways to develop highly specific drugs designed to kill leukemia cells while causing few or no toxic effects on normal cells.

A five-year, $6.25 million Specialized Center of Research (SCOR) grant from the Leukemia & Lymphoma Society brings together a diverse study team of researchers from leading medical centers to develop innovative treatments for infant leukemia. "Our goal is to streamline advances in molecular medicine to find new treatment options," said Carolyn A. Felix, M.D., principal investigator of the SCOR grant. A pediatric oncologist at The Children's Hospital of Philadelphia, Dr. Felix also is a professor of Pediatrics at the University of Pennsylvania School of Medicine.

The society recently announced its grant award in targeted therapies for infant leukemia from its national office in White Plains, N.Y. The SCOR grant draws on research collaborators from a variety of disciplines to discover new approaches to treatment.

In addition to researchers from The Children's Hospital of Philadelphia and the University of Pennsylvania, the grant includes collaborators from the University of New Mexico, Johns Hopkins University, Stanford University and Tulane University.

Especially integral to this effort to advance new treatments from bench to bedside, the investigators also will work closely with the Children's Oncology Group, the cooperative clinical research organization of pediatric cancer centers throughout North
'"/>

Contact: John Ascenzi
Ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia
5-Dec-2006


Page: 1 2 3

Related biology news :

1. Doernbecher Childrens Hospital scientist earns coveted Javits award
2. NIH selects Childrens Hospital as Center of Excellence to train future generations of scientists
3. Childrens Hospital Oakland, Calif.s new iron regulation discovery
4. Childrens Hospital Oaklands new maternal diet study
5. Childrens Hospital and Research Center-Oakland presents a new maternal diet study
6. Childrens Hospital Boston presents at the 2006 American Academy of Pediatrics National Conference
7. Genetic research at Childrens Hospital of Pittsburgh reinforces theory of evolution
8. Childrens Hospital Boston presents at the 2006 Pediatric Academic Societies annual meeting
9. UCLA engineering and Mattel Childrens Hospital collaborate to develop childrens heart valve
10. Childrens Hospital Oakland scientist awarded seat on national scientific review board
11. Research center for National Childrens Study to be based in Queens

Post Your Comments:
(Date:11/23/2009)...nts gathered this week for the seventh annual Nati... This year,s topic, "Synthetic Biology," brought t...hers to explore the engineering, scientific, and s...thetic biology. , Bonnie L. Bassler, professor o...is year,s conference chair, challenged the attende...
(Date:11/23/2009)...incontrovertible evidence" that the volcanic super...3,000 years ago deforested much of central India, ...eport. , The volcano ejected an estimated 800 cu... a crater (now the world,s largest volcanic lake) .... Ash from the event has been found in India, the ...
(Date:11/23/2009)...the highest resolution images of peptides attachin...derstanding how biomolecules manipulate the growth...nt for kidney stones using biomolecules. , The r...on of the journal Proceedings of the National Aca...with mineral surfaces by accelerating, switching a...
Breaking Biology News(10 mins):Synthetic biology offers new opportunities for interdisciplinary collaboration 2Supervolcano eruption -- in Sumatra -- deforested India 73,000 years ago 2Scientists watch as peptides control crystal growth with 'switches, throttles and brakes' 2Scientists watch as peptides control crystal growth with 'switches, throttles and brakes' 3Barriers Hinder EMS Workers From Using Best Resuscitation Practices 50465 1Barriers Hinder EMS Workers From Using Best Resuscitation Practices 50465 2Barriers Hinder EMS Workers From Using Best Resuscitation Practices 50465 3Barriers Hinder EMS Workers From Using Best Resuscitation Practices 50465 4Excalibur International Marine 2849 25 Owned by EFT BioTech Holdings 29 Completes Inaugural Passenger Crossing of Taiwan Strait 12858 1Excalibur International Marine 2849 25 Owned by EFT BioTech Holdings 29 Completes Inaugural Passenger Crossing of Taiwan Strait 12858 2Excalibur International Marine 2849 25 Owned by EFT BioTech Holdings 29 Completes Inaugural Passenger Crossing of Taiwan Strait 12858 3Keep Mosquitoes and More Out of Your Yard with Garlic From Garlic Research Labs Inc 4672 1Keep Mosquitoes and More Out of Your Yard with Garlic From Garlic Research Labs Inc 4672 2
(Date:11/25/2009)... Ambassador to Speak at Economic Club...ada (Vocus) November 25, 2009 -- Ambassador to Spe...d Appia, French Ambassador for International Inves...e Agency ,To view a biography of David Appia go to... Appia is available to meet with press to discuss ...
(Date:11/25/2009)...IEGO,Nov.25/PRNewswire-FirstCall/--ArdeaBioscience...t,Pharm.D.,presidentandchiefexecutiveofficer,willp...nce. , ,Presentationdetailsareasfollows:,PiperJa...ecember1,2009,Time:2:00p.m.EasternTime,Location:Th...p://www.corporate-ir.net/ireye/,target=,_blank,ti...
(Date:11/24/2009)...ACRUZ,Calif.,Nov.24/PRNewswire/--Twomoreprestigiou...leadingonlinejobboardandcareerssiteforlifesciencep...ityarenowmembersofthejobboard,joining28othermajorl... www.biocareercenter.com ,isonlyforpost-graduatesi...ecareersitesontheInternet,BioCareerCenteristheonly...
(Date:11/24/2009)...JAVIK,Iceland,November24/PRNewswire-FirstCall/--de...approvalofallofits,"firstday"motionsbytheU.S.Bankr...Court").deCODElastweekfiledavoluntarypetitionfor,r...withthe,BankruptcyCourt. , Theordersissuedbyt...teitsbusinessduringtheChapter11proceedings.Inparti...
Breaking Biology Technology:French Ambassador for International Investment to Visit Toronto December 11 2Ardea Biosciences to Present at the Piper Jaffray 21st Annual Health Care Conference 2Two Major Universities Join Nation's Leading Postgrad Bio Job Board 2deCODE genetics, Inc. Announces Approval of First Day Motions by Bankruptcy Court 2deCODE genetics, Inc. Announces Approval of First Day Motions by Bankruptcy Court 3
Other News:
...Feuchtmayr and a team from the School of Biologica...llaboration with scientists from Belgium, Germany,...predicted rise in climate temperature for the UK a...lgae in the country's lakes and ponds.......The pr...
For more than 40 years, a scientific controversy has raged over whether microsaccades, rapid eye movements that occur when a person's gaze is fixated, are responsible for visibility. ......Research co
...one helps hundreds of children with a rare disorde... starting treatment can worsen a dangerous nightti...chers have found.......Sleep apnea disrupts breath...e children, including those with Prader-Willi synd...
...al cages created by researchers at Rutgers, The St...elivering drugs to organs or tissues where they're... cage-like molecules, called nanocontainers or nan...nometers (billionths of a meter) wide, also could ...
Europe's largest climate change experiment launched 2Growth hormone, obesity can trigger sleep apnea in some kids 2Growth hormone, obesity can trigger sleep apnea in some kids 3Rutgers researchers create tiny chemical cages to enclose drug, pesticide molecules 2
...t Daniel R. Gallie at the University of California...odd Young, Jun Ling, and Su-Chih Chang report in t... National Academy of Sciences (PNAS) that they hav...f vitamin C in plants, including grains, by increa...
...unterpart causes inherited glaucoma in humans, res...at worsens the structural eye defect that causes t...ene mutation affects production of L-DOPA. The res...ent glaucoma by administering L-DOPA, which is use...
...archers have been selected as the only Canadian ho...rvosa ever conducted.......The National Institute ...million (US) project, led by University of Pittsbu...ps of researchers from North America and Europe (1...
...s the same day they are discovered could reduce ce...ng to a study of Thai women by researchers at John... of the study, published in the March 8 issue of T...nt led to high rates of compliance with recommende...
UC Riverside biochemists develop technology to increase Vitamin C in plants 2UC Riverside biochemists develop technology to increase Vitamin C in plants 3Researchers identify new gene mutation in glaucoma 2Researchers identify new gene mutation in glaucoma 3Toronto General Hospital to be only Canadian site in first-ever genetic study of anorexia nervosa 2'One-stop' approach works well for cervical cancer prevention 2'One-stop' approach works well for cervical cancer prevention 3