HOME >> BIOLOGY >> NEWS
Chromosomal microarray analysis proves accurate

Two years and more than 2,000 samples after researchers at Baylor College of Medicine started to use a new gene-chip technology called chromosomal microarray analysis to look for potential genetic abnormalities in children, they find that it is remarkably sensitive in detecting abnormalities in individual chromosomes, according to a report that appears online today in the journal Public Library of Science ONE.

"Chromosomal microarray analysis is far better at picking up these abnormalities than other common methods," said Dr. Arthur Beaudet, chair of the department of molecular and human genetics at BCM and an author of the paper. "It allows us to identify the source of abnormalities in many cases."

He said the technique does not help with identifying the problem in all children, but there is a five to 12 percent chance that it will identify an abnormality in children with various disabilities where the previous chromosomal testing did not. This study involved two versions of the test, and the newer version was more successful in identifying chromosomal abnormalities.

The targeted microarray analysis used here is essentially a gene chip method of assessing the makeup of chromosomes in a particular part of the human genome (genetic blueprint).

In areas of the genome, there are portions of the genetic material that show imbalances because they are duplicated or deleted abnormally with gains and losses of genetic information.

"If these changes are big enough, they can cause significant disabilities," said Beaudet.

The technique used is also much more efficient, making it possible to do the equivalent of a couple of thousand of more common testing methods in one test.

"If you tried to do these individually, it would be cost prohibitive," said Beaudet. Currently, chromosomal microarray analysis costs from $950 to $1,500.

In the current study, Beaudet and his colleagues analyzed the result
'"/>

Contact: Ross Tomlin
htomlin@bcm.edu
713-798-4710
Baylor College of Medicine
28-Mar-2007


Page: 1 2

Related biology news :

1. Chromosomal tests can determine brain tumor therapy, outcomes, Jefferson oncologists find
2. Chromosomal abnormalities in sperm higher after vasectomy reversal
3. NIH neuroscience microarray consortium launches high-throughput genotyping services
4. Study identifies common flaws in oncology microarray studies
5. Bayer HealthCare licenses Genomatix for microarray analysis
6. Carnegie Mellon U. transforms DNA microarrays with standard Internet communications tool
7. Different microarray systems more alike than previously thought
8. Standardized microarrays may bring us one step closer
9. AAAS analysis finds Congress would add billions to FY 2008 R&D investment
10. Genetic analysis finds greater threat in frog-killing fungus
11. Genomic analysis uncovers new targets for HIV vaccine

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Chromosomal microarray analysis proves accurate

(Date:7/2/2015)... 2, 2015 Fingerprint Cards has received ... and FPC1155 from the distributor World Peace Industrial Group (WPI), ... in Asia . Deliveries are planned to ... be used by smartphone manufacturers in Asia ... the communicated revenue guidance of approximately 2,200 MSEK for 2015. ...
(Date:6/25/2015)... , June 25, 2015 ... Sensors Market by Type (Swipe & Area), Technology, Material ... Government, Healthcare, Commercial Security & Others) & Geography ... by marketsandmarkets, the said market is expected to ... of 17.1%. Browse 76 market ...
(Date:6/24/2015)... 24, 2015  Synaptics Inc. (NASDAQ: SYNA ... today announced that Sharp has selected its industry-leading ... for its latest flagship smartphone device, the AQUOS ... million shipments of its fingerprint ID sensor technology, ... scalability and leadership in the biometrics market through ...
Breaking Biology News(10 mins):FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 3Fingerprint Sensors Market Worth $14,500.07 Million by 2020 4Synaptics Brings Natural ID Technology to Sharp's Newest Flagship Smartphone 2
(Date:7/24/2015)...  Champions Oncology (OTC-BB: CSBR), a company engaged in ... personalize the development and use of oncology drugs, today ... for the fourth quarter and fiscal year quarter ended ... market open. The company will host a ... 9:00 a.m. EDT (6:00 a.m. PDT). To participate in ...
(Date:7/24/2015)... ... July 24, 2015 , ... RURO’s ... modern scientific or pharmaceutical laboratory. FreezerPro® is an intuitive, fast, reliable and ... a sample is located even before opening the freezer door! Popular features ...
(Date:7/23/2015)... , July 23, 2015 The Hong Kong ... given the prestigious accolade of "Most Innovative Technology ... world-class position in fostering innovation and technology development ... region.  The award has ... innovation and technology magazine and website with a ...
(Date:7/23/2015)... 2015 OncoSec Medical Incorporated ("OncoSec") (NASDAQ: ... invites investors and the general public to its Annual ... Friday, July 31, 2015. The meeting will be held ... San Diego, California 92121.   ... also be available. Please use the following link to ...
Breaking Biology Technology:Champions Oncology to Announce Fourth Quarter Financial Results on Tuesday, July 28 2RURO, Inc. Partners with Integrated Systems Engineering to Provide Comprehensive LIMS Software to Biobanks 2RURO, Inc. Partners with Integrated Systems Engineering to Provide Comprehensive LIMS Software to Biobanks 3RURO, Inc. Partners with Integrated Systems Engineering to Provide Comprehensive LIMS Software to Biobanks 4HKSTP Wins Most Innovative Technology Hub at The New Economy Awards 2015 2HKSTP Wins Most Innovative Technology Hub at The New Economy Awards 2015 3OncoSec to Webcast Annual Meeting of Stockholders 2
Cached News: