HOME >> BIOLOGY >> NEWS
Chromosome regions containing genes related to alcohol addiction affect drinking behavior in smokers

Scientists have found in a study of tobacco users that their drinking behavior is linked to some of the same chromosome regions associated with alcohol addiction.

The study, published in the December issue of the journal Alcoholism: Clinical & Experimental Research, offers evidence that the interaction between smoking and alcohol consumption may partly be due to overlapping genetic risk factors. The results also provide further confirmation that alcoholism is a complex behavior drawing from both environmental and genetic factors.

"Since we know that people who drink often smoke and that smokers often drink, we thought it reasonable to collect some information about the drinking behavior in these families," said lead study author Dr. Kirk C. Wilhelmsen, associate professor in the departments of genetics and neurology at the University of North Carolina at Chapel Hill's School of Medicine.

He also is a member of the Carolina Center for Genome Sciences, the Bowles Center for Alcohol Studies and the UNC Lineberger Comprehensive Cancer Center.

The research team studied 158 families that had at least two first-degree relatives who had smoked 100 or more cigarettes in their lifetime. These included any combination of parents, siblings and offspring who had smoked.

A detailed questionnaire was used to search for alcohol-related behavioral traits, or phenotypes, shared within each family. Questions concerned the quantity of alcohol consumed, such as the number of alcohol drinks per month for six consecutive months and the number of alcohol of drinks consumed in a typical week and typical day.

DNA from blood samples taken from each family participant was analyzed for particular genetic variations. "We looked for excess chromosome sharing of regions that had genes that affect patterns of drinking behavior," Wilhelmsen said.

The researchers applied linkage analysis, which examines differences, or variants, in the
'"/>

Contact: Les Lang
llang@med.unc.edu
919-843-9687
University of North Carolina School of Medicine
22-Dec-2005


Page: 1 2

Related biology news :

1. Chromosome glue repairs damaged DNA
2. Chromosome rearrangements not as random as believed
3. Chromosome four contains genes that affect drinking behaviors in smokers
4. Chromosome deletion predicts aggressive neuroblastoma
5. Chromosome 16 publication fulfills DOEs human genome commitment
6. Strength of connections between brain regions may affect an adolescents response to peer influence
7. Steroids, not songs, spur growth of brain regions in sparrows
8. Study finds regions of DNA that appear linked to autistic spectrum disorders
9. Study challenges idea that schizophrenia is distinct in developing and developed regions
10. Exploring polar regions, understanding climate
11. Studies identify DNA regions linked to nicotine dependence

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2020)... MANSFIELD, Mass. (PRWEB) , ... June 24, 2020 ... ... provider of cloud-based enterprise software and software-driven clinical data services that accelerate drug ... trials for low-dose selinexor, an XPO1 inhibitor, in hospitalized patients with severe COVID-19. ...
(Date:6/23/2020)... ... June 23, 2020 , ... First ... Renovagen Ltd, a UK supplier and manufacturer of innovative portable renewable energy equipment, ... in the fight against the COVID-19 pandemic in Zambia. , One of Renovagen’s ...
(Date:6/23/2020)... THE WOODLNDS, Texas (PRWEB) , ... June 23, ... ... in X-ray analytical instrumentation, is pleased to announce the next event in a ... of X-ray scattering. , The TOPIQ series of webinars was developed in response ...
Breaking Biology News(10 mins):
(Date:8/31/2020)... ... August 29, 2020 , ... DuPont Nutrition & ... Wuxi, China. The new plant operation will provide the local animal production industry ... , “This facility will improve the flexibility of our offerings to the Chinese ...
(Date:8/12/2020)... ... August 11, 2020 , ... ... is making available for free its new white paper – Simulated Transport ... testing into today’s biologics licensing application (BLA). In response, Modality Solutions shares ...
(Date:8/3/2020)... ... August 03, 2020 , ... Introducing Ardent Animal Health ... growth, , Known as MediVet Biologics since its formation in ... The new Ardent Animal Health will build on its base of innovative therapies ...
(Date:7/31/2020)... ... July 29, 2020 , ... Anomet Products has introduced new ... for use with CRM, neurostimulation, vascular, and related devices. , Anomet Medical ... requirements, performance, and cost criteria; especially where solid wire is limited. Typical configurations ...
Breaking Biology Technology:
Cached News: