HOME >> BIOLOGY >> NEWS
Chronic drinking and smoking cause both separate and interactive brain injury

interactions are also influenced by genetic factors. Therefore, co-morbidity of drinking and smoking can be considered to be a final outcome of genetics, environment, and pharmacological interactions between alcohol and nicotine."

- Smoking may attenuate gamma-aminobutyric acid (GABA)A receptor adaptations associated with alcohol dependence and may contribute to the co-occurrence of alcoholism and smoking. In light of this, benzodiazepines used to treat alcohol withdrawal may have different effects on alcohol-dependent individuals who smoke versus those who do not.

"GABA is an inhibitory amino acid in the human brain and is critical in counterbalancing the biological action of the excitatory amino acid glutamate," explained Meyerhoff. "In a healthy human brain, both amino acids are present in equilibrium. In disease stages such as addiction, to either alcohol or nicotine, this equilibrium is out of balance. During alcohol withdrawal, GABA concentrations may increase, but the densities of receptors are still relatively low. Benzodiazepines may strengthen the responses of (GABA)A receptors to GABA binding, thereby having a soothing effect on the user."

- In-vivo magnetic resonance studies suggest that chronic smoking in recently detoxified alcohol-dependent individuals compounds alcohol-induced brain tissue loss and neuronal injury. Chronic smoking may also hinder neurobiological and cognitive recovery during short-term abstinence from alcohol.

"We studied recently detoxified alcoholics in treatment using in-vivo magnetic resonance," said Meyerhoff. "The specific methods we used were magnetic resonance imaging (MRI), which measures the size of many different brain structures, and magnetic resonance spectroscopic imaging (MRSI), which measures certain naturally occurring chemicals in the brain that tell us about injury to specific brain cells. Our analyses showed that chronically smoking alcoholics have greater
'"/>


24-Jan-2006


Page: 1 2 3 4

Related biology news :

1. Chronic fatigue -- clues in the blood
2. Chronically sleep deprived? You cant make up for lost sleep
3. Chronic jet-lag conditions hasten death in aged mice
4. Chronic neuropathic, phantom pain comes from affected nerve and spinal cord, not brain
5. Chronic oil pollution takes toll on seabirds along South American coast
6. Chronic stress might harm women more than it does men
7. Chronic stress accelerates atherosclerosis following angioplasty procedure
8. Chronic inflammation caused by too little stomach acid leads to gastric cancer
9. Not so contoversial anymore -- panel says moderate coffee drinking reduces many risks
10. Monochloramine treatment not as effective in protecting drinking water
11. New UD technology removes viruses from drinking water

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/9/2016)... Paris Police Prefecture ... solution to ensure the safety of people and operations in ... major tournament Teleste, an international technology group specialised ... today that its video security solution will be utilised by ... public safety across the country. The system roll-out is scheduled ...
(Date:6/2/2016)... 2016 Perimeter Surveillance & Detection ... Physical Infrastructure, Support & Other Service  The ... offers comprehensive analysis of the global Border Security ... revenues of $17.98 billion in 2016. Now: ... leader in software and hardware technologies for advanced video ...
(Date:5/12/2016)... , May 12, 2016 WearablesResearch.com ... just published the overview results from the Q1 wave ... the recent wave was consumers, receptivity to a program ... data with a health insurance company. "We ... to share," says Michael LaColla , CEO of ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 2016 A person commits a crime, and the ... track the criminal down. An outbreak of foodborne ... Administration (FDA) uses DNA evidence to track down the bacteria ... far-fetched? It,s not. The FDA has increasingly used a complex, ... foodborne illnesses. Put as simply as possible, whole genome sequencing ...
(Date:6/23/2016)... -- The Prostate Cancer Foundation (PCF) is pleased to announce 24 new ... prostate cancer. Members of the Class of 2016 were selected from a pool ... Read More About the Class of 2016 PCF Young Investigators ... ... ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... announced the launch of the Supplyframe Design Lab . Located in Pasadena, ... explore the future of how hardware projects are designed, built and brought to ...
(Date:6/23/2016)... Apellis Pharmaceuticals, Inc. today announced positive ... its complement C3 inhibitor, APL-2. The trials were ... studies designed to assess the safety, tolerability, pharmacokinetics ... healthy adult volunteers. Forty subjects were ... dose (ranging from 45 to 1,440mg) or repeated ...
Breaking Biology Technology:
Cached News: