HOME >> BIOLOGY >> NEWS
Clinical trial for diabetic macular edema

March 26, 2007 New York, NY -- The Juvenile Diabetes Research Foundation, the worlds largest charitable funder of type 1 diabetes research, announced that the Ranibizumab for Edema of the mAcula in Diabetes Phase 2 Study (READ 2) is now enrolling patients.

The READ 2 Study will test the long-term safety and effectiveness of intraocular injections of ranibizumab in patients with diabetic macular edema (DME), a condition characterized by swelling of the retina due to leaking of fluid from blood vessels within the macula. DME is the leading cause of vision loss among working-age Americans.

The READ2 study is supported by Genentech and JDRF. The Phoenix-based Retinal Consultants of Arizona will serve as a clinical center for the trial.

This Phase 2 clinical trial builds on the results of a phase 1 trial (which was supported by an Innovative Grant Award from JDRF), which showed the ability of ranibizumab to improve visual acuity in patients with diabetic macular edema. Visual acuity was assessed using a reading chart, and median and mean visual acuity improved by 11 and 12.3 letters respectively at 7 months. This corresponds to the ability to read two additional lines on a reading chart. In the phase 1 study, there were no adverse events that were judged by the investigators to be related to the drug. Some patients experienced redness on the surface of the eye at the site of injection that lasted up to 72 hours. The redness was thought to be due to the injection itself, however, and not the drug.

The READ 2 study will look specifically for additional dosing and safety information, as well as combination therapy of ranibizumab and laser photocoagulation (which has been the standard therapy for DME). The study consists of a two-week screening period, a six-month active treatment period, and an 18-month follow-up and treatment period.


'"/>

Contact: Eileen Brangan
ebrangan@jdrf.org
212-479-7577
Juvenile Diabetes Research Foundation International
26-Mar-2007


Page: 1

Related biology news :

1. 2007-2008 Genzyme/ACMGF Clinical Genetics Fellowship In Biochemical Genetics award winner announced
2. Scientists honored with Excellence in Clinical Research Award
3. Clinical trial data regarding NKTR-061 will be presented at ATS International Conference
4. The Parkinsons Institute to conduct Phase III Clinical Trial of creatine for Parkinsons disease
5. Research and program highlights of the 2007 Annual Clinical Genetics Meeting, March 21-25, 2007
6. American College of Medical Genetics -- 2007 Annual Clinical Genetics Meeting Announcement
7. October MCP: A special issue on Clinical Proteomics
8. Columbia University Medical Center receives major new NIH Clinical Science investment funds
9. Researchers reverse juvenile diabetes in animal model; Clinical trial FDA approved
10. Clinical trial to test stem cell approach for children with brain injury
11. Vaccine trials inject hope into koalas future

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/7/2020)... ... August 06, 2020 , ... ... pleased to announce that Eric Chen and Jessica Wong have joined the company’s ... & Strategy, respectively. , Eric Chen heads development efforts for Alucio’s flagship product, ...
(Date:7/31/2020)... , ... July 30, 2020 , ... ... (SBIR) Phase II contract awarded by the Joint Science & Technology Office—Chemical and ... project is to develop, optimize, and scale-up a highly efficient mammalian cell culture-based ...
(Date:7/18/2020)... ... ... Commercial launch readiness is a critical stage in a product life cycle. ... the global economic downturn will only increase price pressures overall for the industry. The ... value from every product launch is critical. However, history shows that only a third ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... July 29, 2020 , ... Editas Medicine, Inc. ... of advanced delivery technologies, development, and manufacturing solutions for drugs, biologics, cell and ... a strategic partnership whereby Catalent will provide support for the development, manufacturing, and ...
(Date:7/31/2020)... ... July 29, 2020 , ... The ... centers in 16 countries, has reached its 20th anniversary of worldwide use. Introduced ... use at top universities including University of Pennsylvania, University of Michigan, University of ...
(Date:7/22/2020)... ... July 22, 2020 , ... Join experts from Reed Tech , ... Solutions, in a one hour live webinar on Thursday, August 13, 2020 ... for drugs and medical devices. Specifically, for medical devices, the NMPA has departments dealing ...
(Date:7/18/2020)... ... 2020 , ... “We are thrilled to deliver this new technology to the ... its kind on the market and we were pleased that the IFT jury recognized ... cultured ingredients, creating a natural way to extend the shelf life and improve the ...
Breaking Biology Technology:
Cached News: