HOME >> BIOLOGY >> NEWS
Clinical trial to test stem cell approach for children with brain injury

HOUSTON -- (Dec. 20, 2005) A unique clinical trial will gauge the safety and potential of treating children suffering traumatic brain injury with stem cells derived from their own bone marrow starting early next year at The University of Texas Medical School at Houston and Memorial Hermann Children's Hospital.

The clinical trial is the first to apply stem cells to treat traumatic brain injury. It does not involve embryonic stem cells.

"There is no reparative treatment for traumatic brain injury," said principal investigator Charles Cox, M.D., The Children's Fund, Inc. Distinguished Professor in Pediatric Surgery and Trauma at the medical school. "All we can do now is try to prevent secondary damage by relieving pressure on the brain caused by the initial injury."

Unlike bone, muscle and other organs, the brain does not repair itself effectively. Traumatic brain injury victims can regain some function through rehabilitation. Studies show between 15 and 25 percent of children suffering severe traumatic brain injury die, and survivors of even moderate injury often are devastated for life.

Approved by the U.S. Food and Drug Administration and the university's Committee for the Protection of Human Subjects (CPHS), the clinical trial builds on laboratory and animal research indicating that bone-marrow derived stem cells can migrate to an injured area of the brain, differentiate into new neurons and support cells, and induce brain repair.

"This would be an absolutely novel treatment, the first ever with potential to repair a traumatically damaged brain," said James Baumgartner, M.D., associate professor of pediatric neurosurgery and co-principal investigator on the project.

As a Phase I clinical trial, the project's first emphasis is to establish the safety of the procedure, with a secondary goal of observing possible therapeutic effects.

Cox and Baumgartner have permission to recruit 10 head injury p
'"/>

Contact: Scott Merville
scott.merville@uth.tmc.edu
713-500-3042
University of Texas Health Science Center at Houston
20-Dec-2005


Page: 1 2 3

Related biology news :

1. 2007-2008 Genzyme/ACMGF Clinical Genetics Fellowship In Biochemical Genetics award winner announced
2. Scientists honored with Excellence in Clinical Research Award
3. Clinical trial data regarding NKTR-061 will be presented at ATS International Conference
4. Clinical trial for diabetic macular edema
5. The Parkinsons Institute to conduct Phase III Clinical Trial of creatine for Parkinsons disease
6. Research and program highlights of the 2007 Annual Clinical Genetics Meeting, March 21-25, 2007
7. American College of Medical Genetics -- 2007 Annual Clinical Genetics Meeting Announcement
8. October MCP: A special issue on Clinical Proteomics
9. Columbia University Medical Center receives major new NIH Clinical Science investment funds
10. Researchers reverse juvenile diabetes in animal model; Clinical trial FDA approved
11. Vaccine trials inject hope into koalas future

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Clinical trial test stem cell approach for children with brain injury

(Date:7/27/2015)... , July 27, 2015  Synaptics Inc. ... human interface solutions, today announced that Huawei has ... touchscreen solution for its stylish smartwatch. Huawei chose ... proven reliability, low power and highly responsive human ... finger. Huawei designers also required a classic round ...
(Date:7/27/2015)... LOS ANGELES , July 27, 2015 /PRNewswire/ ... providing evidence- and experience-based clinical improvement solutions, today ... coordination solution is now available on Android smartphones ... at inpatient and post-care organizations can use ZynxCarebook ... the same patient,s condition, streamline care transitions to ...
(Date:7/23/2015)... (NASDAQ: AWRE ), a leading supplier of biometrics software ... ended June 30, 2015.  Revenue for the ... 33% compared to $6.8 million in the same quarter last ... $0.3 million, or $0.01 per diluted share, which compared to ... period a year ago.  Lower revenue and ...
Breaking Biology News(10 mins):Synaptics Touchscreen Solution Powers New Huawei Watch 2Synaptics Touchscreen Solution Powers New Huawei Watch 3Zynx Health Adds Android Device Support to ZynxCarebook Solution 2Zynx Health Adds Android Device Support to ZynxCarebook Solution 3Aware, Inc. Reports Second Quarter 2015 Financial Results 2Aware, Inc. Reports Second Quarter 2015 Financial Results 3Aware, Inc. Reports Second Quarter 2015 Financial Results 4Aware, Inc. Reports Second Quarter 2015 Financial Results 5Aware, Inc. Reports Second Quarter 2015 Financial Results 6
(Date:7/23/2015)... , July 23, 2015 ImmunoCellular Therapeutics, Ltd. ("ImmunoCellular") ... financial results for the second quarter 2015 on Thursday, August ... call and webcast on that day at 5:00 pm ET ... a business update. The call will be hosted by ... , , , LIVE CALL: , , ...
(Date:7/23/2015)... , ... July 23, 2015 , ... One hundred years ... the 1915 National Model Aeroplane Competition, with hopes of winning the Henry S. Villard ... its centennial. , Participants will have the opportunity to build a Free Flight fantasy ...
(Date:7/23/2015)... ... ... The Pittcon 2016 Program Committee is extremely pleased to announce that W. ... courtesy, of Applied Physics at Stanford University, will present the Wallace H. Coulter ... Cells and Beyond” , Dr. Moerner’s lecture will focus on his research in ...
(Date:7/23/2015)... OncoSec Medical Incorporated ("OncoSec") (NASDAQ: ONCS ... investors and the general public to its Annual Shareholder ... July 31, 2015. The meeting will be held at ... San Diego, California 92121.   ... be available. Please use the following link to register ...
Breaking Biology Technology:ImmunoCellular Therapeutics to Report Second Quarter 2015 Financial Results on August 6, 2015 2Academy of Model Aeronautics to Start Online Fantasy Flight Competition 2The 2014 Nobel Prize in Chemistry Recipient W. E. Moerner, to Deliver Wallace H. Coulter Lecture at Pittcon 2016 2The 2014 Nobel Prize in Chemistry Recipient W. E. Moerner, to Deliver Wallace H. Coulter Lecture at Pittcon 2016 3OncoSec to Webcast Annual Meeting of Stockholders 2
Cached News: