HOME >> BIOLOGY >> NEWS
Coding for arthropods - what's so special about insects and spiders?

The central dogma of molecular biology is that DNA makes RNA makes protein. This relies on a specific underlying code which relates given triplets of RNA nucleotides into specific amino acids. Each of the 20 amino acids is represented by one or more RNA triplets, or codons: UAC is decoded as tyrosine, for example, and UGC as cysteine. (U is the RNA nucleotide containing uracil, A is adenine, C is cytosine, and G is guanine.) For some time the code had been thought to be the same in all organisms. But exceptions have been seen before, particularly in mitochondria.

In a new study published online this week in the open-access journal PLoS Biology, Federico Abascal, Rafael Zardoya, and colleagues show that in the mitochondria of arthropod there are two nonstandard codes, and suggest that genetic code changes within a lineage may be more frequent than was earlier believed.

The authors aligned the mitochondrial coding sequence from >600 animal species looking for conserved codons and identifying which amino acid (AA) it specified in the corresponding protein. The most frequent AA was taken to be the canonical translation of that codon. What they found was that although most codons adhered to the common genetic code in all species, there was nonetheless a surprising trend in the arthropods, the largest of all animal phyla. Typically, AGG translates as the amino acid serine. However, among the arthropod mitochondrial genomes, AGG coded for serine in some species and lysine in others. The authors' analysis of the patterns of change also suggests that the original arthropod mitochondrion used AGG for lysine, not serine.

The observed variety suggests the code has changed multiple times between the two genetic codes. It might be that pairing of AGG and lysine is disadvantageous for the organism employing it, so that loss or reversion over time would be favored. This might also suggest the existence of multiple other nonstandard codes within other linea
'"/>

Contact: Paul Ocampo
press@plos.org
415-624-1224
Public Library of Science
24-Apr-2006


Page: 1 2

Related biology news :

1. Natural anti-freeze -- how arthropods survive the cold
2. Diffraction and scattering -- the solution to whats in solution
3. Parental genes do whats best for baby
4. Where the brain combines whats heard and felt
5. The Academy of Natural Sciences probes whats eating historic USS Monitor
6. Hey, now, whats that sound
7. Eat fish -- especially if you drink high levels of alcohol
8. Stem cell specialists face questioning
9. Cancer research specialist and HSPH professor awarded Medal of Honor from WHO cancer agency
10. Cannibalism of the young allows individual fish to specialize
11. Researchers find level of special protein is critical to proper formation of muscles

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/15/2019)... ... August 15, 2019 , ... Make ... staff of routine tasks. That was the message at the world's largest gathering ... Information. The American Association for Clinical Chemistry (AACC) Annual Scientific Meeting was held ...
(Date:8/14/2019)... ... August 14, 2019 , ... Join Jonathan Riek, PhD, VP, ... on Tuesday, September 10, 2019 at 1pm EDT to learn about two common imaging ... , NAFLD is the most common diffuse liver disease, with a worldwide prevalence ...
(Date:8/14/2019)... ... August 13, 2019 , ... Join Anguraj Sadanandam, PhD, Team ... Cancer Research (ICR) in a live webinar on Wednesday, September 4, ... and companion diagnostic development including machine learning approaches in different gastrointestinal cancers and ...
Breaking Biology News(10 mins):
(Date:7/9/2019)... ... July 08, 2019 , ... Balluff has ... was recognized as the 2019 Innovative Product of the Year which highlights cutting-edge ... were during Sensors Expo & Conference 2019, held this week in ...
(Date:6/26/2019)... ... June 26, 2019 , ... Alice Branton today released research results from preclinical ... Magnesium Gluconate, which can prove to be beneficial for treating Hypomagnesemia. , The preclinical ... change in crystallite size , Over 142% increase in particle size , ...
(Date:6/18/2019)... (PRWEB) , ... June 18, 2019 , ... Personalized ... Investigational New Drug (IND) application to the FDA for use of a person’s own ... as a treatment of osteoarthritis in the knee. This IND is the first ...
(Date:6/11/2019)... , ... June 10, 2019 , ... ... its distribution network with the appointment of Biofeedback Tech Ltd as ... systems are an essential part of many therapeutic treatments and clinical assessment protocols ...
Breaking Biology Technology:
Cached News: