HOME >> BIOLOGY >> NEWS
Coffee, black, decaf and a little llama on the side

St. Louis, May 11, 2006 -- Three llamas and two camels have provided a way to tell whether your waiter swapped regular coffee for decaf in your after-dinner cup. Using the heat-resistant antibodies these camels and llamas make, researchers at Washington University School of Medicine in St. Louis are developing a quick test for caffeine that works even with hot beverages.

The researchers plan to adapt their technology to a simple test ("dipstick") that can be used to check for caffeine in a variety of drinks. Their research will appear in the June 1 issue of the American Chemical Society's journal Analytical Chemistry.

Caffeine can cause restlessness, irritability, dehydration or heart arrythmias, and those who are highly sensitive to caffeine can feel its stimulant effects for as long as 20 hours. In addition, some medicines adversely interact with caffeine.

"We believe our test would be the first consumer test for caffeine and would be beneficial for anyone wishing to avoid caffeine for health or personal reasons," says senior author Jack H. Ladenson, Ph.D., the Oree M. Carroll and Lillian B. Ladenson Professor of Clinical Chemistry and director of the Division of Laboratory Medicine.

Interestingly, the key to the caffeine test comes from llamas and camels -- pack animals that have transported caffeinated commodities such as coffee, tea and cocoa for centuries. These camelids happen to be among the few creatures whose immune systems can produce antibodies that aren't destroyed at the high temperatures common to brewed beverages.

The researchers reasoned that if they could create heat-resistant camelid antibodies that reacted to caffeine, they could potentially build a durable assay suitable for use almost anywhere. They gave intramuscular injections of a caffeine-linked protein to three llamas and two camels to elicit an immune response to caffeine. They found that blood from the animals contained antibodies that were heat-stable and re
'"/>

Contact: Gwen Ericson
ericsong@wustl.edu
314-286-0141
Washington University School of Medicine
11-May-2006


Page: 1 2 3

Related biology news :

1. Emory chemists develop bacteria that may help decaffeinate coffee
2. Learning to evolve: With a little help from my ancestors
3. Study led by Scripps Research scientist reveals little-known cell networks vital to circadian rhythm
4. Local interventions have little effect on metapopulation stability
5. Marathon mice elucidate little-known muscle type
6. A little of what you fancy does you no good
7. Universal design tackles little things with big impact
8. Eating less fat may lower breast-cancer risk, have little impact on colon-cancer, heart-disease risk
9. Earliest European farmers left little genetic mark on modern Europe, Science study finds
10. Major losses projected for earthquake on little-known fault under Los Angeles
11. Marshes tell story of medieval drought, little ice age, and European settlers near NYC

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/10/2020)... Va. (PRWEB) , ... July 08, 2020 , ... ... Latest on Cell and Gene Therapy Regulation, An FDAnews Webinar, Wednesday, July 22, ... need a comparability study, but what is the most effective way to complete ...
(Date:7/2/2020)... ... July 02, 2020 , ... ... announced a publication detailing the use of its revolutionary NEXTGENPCR endpoint thermocycler ... (RT-PCR) in 16 minutes. The article, titled "Ultra-fast one-step RT-PCR protocol for ...
(Date:6/28/2020)... ... June 25, 2020 , ... In an upcoming episode scheduled ... accelerated Point of Care Testing solutions (POCT). Check local listings for more info. , ... medical offices and are shipped to labs throughout the country. Results are then available ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... July 30, 2020 , ... ... life sciences industry, today announced the release of its signature product called ... Science Liaisons (MSLs) and other field medical professionals. , Beacon helps ...
(Date:7/18/2020)... ... 16, 2020 , ... “We are thrilled to deliver this new technology to ... of its kind on the market and we were pleased that the IFT jury ... traditional cultured ingredients, creating a natural way to extend the shelf life and improve ...
(Date:7/10/2020)... LORTON, Va. (PRWEB) , ... July 08, 2020 ... ... laboratory testing services and products, announces a significant expansion of laboratory operations through ... robust collection for agencies implementing testing programs. , Bode-CARES provides ...
(Date:7/10/2020)... ... July 09, 2020 , ... Sentien Biotechnologies, Inc., a clinical-stage ... Allen R. Nissenson, M.D., F.A.C.P., as its Chief Medical Officer. Dr. Nissenson ... product, SBI-101. Dr. Nissenson serves as an Emeritus Professor of Medicine at ...
Breaking Biology Technology:
Cached News: