HOME >> BIOLOGY >> NEWS
Collaborative Cross to provide powerful resource for mouse model researchers worldwide

OAK RIDGE, Tenn., Sept. 22, 2005 -- A thousand new strains of mice being bred at Oak Ridge National Laboratory as part of an international effort will provide researchers with a powerful resource for studying human disease.

The project, dubbed the Collaborative Cross, has officially begun with a $1.25 million grant over five years from the Ellison Medical Foundation. When completed in about seven years, researchers worldwide will be able to fully exploit the genetic power of the mouse. Each of the estimated 1,000 strains derived from the carefully selected original eight breeds represents a resource that can be used repeatedly to accumulate data.

"Ultimately, this effort will allow us to do a much better job of modeling human populations and diseases because we will have 1,000 lines of mice that carry the kinds of genetic diversity representative of people," said Dabney Johnson, a genetics researcher in ORNL's Life Sciences Division. Johnson headed a team that wrote the proposal to the Ellison Medical Foundation.

At the heart of the project is the new $14 million Laboratory for Comparative Functional Genomics at the Department of Energy's ORNL. The pathogen-free 36,000-square-foot facility completed in 2004 boasts accommodations for 80,000 mice, cryogenic storage and other state-of-the-art features. It is at this designated DOE user facility that the breeding of the eight strains taken from around the world will be performed to initiate up to 1,500 strains of mice. Of those, researchers expect about 1,000 strains to be viable as inbreeding proceeds.

Without DOE's stewardship of the new mouse facility, the project would not be possible, said Johnson, who noted that DOE is contributing not only the space within the facility but also the technical capabilities that will allow the work to be performed.

The project, which will occupy about half of the new ORNL mouse house's capacity, is a perfect fit for ORNL, according to Johnson.
'"/>

Contact: Ron Walli
wallira@ornl.gov
865-576-0226
DOE/Oak Ridge National Laboratory
22-Sep-2005


Page: 1 2 3

Related biology news :

1. Collaborative study successfully applies neutrons to study hydrogen transfer in biological systems
2. A Cross-Disciplinary Look at Scientific Truth: Whats the Law to Do?
3. Crossing the Valley of Death: Moving science into practice and policy
4. Stem Cells: Saving Lives or Crossing Lines?
5. New study suggests Concord grape juice may provide protection against breast cancer
6. Female gender provides an advantage in renal diseases
7. Forecasting system provides flood warnings to vulnerable residents of Bangladesh
8. Discovery of new protein could provide new understanding of male fertility
9. Einstein researchers prototype vaccine could provide improved protection against tuberculosis
10. Genomics study provides insight into the evolution of unique human traits
11. Expert to provide update after worst tomato virus hits California

Post Your Comments:
(Date:3/12/2015)... March 12, 2015 Beta ... identity and access management (IAM) solution for a ... With Beta System,s new IAM package, customers benefit ... gleaned from multiple IAM implementations across different industries. ... as well as any necessary services and consulting. ...
(Date:3/11/2015)... Research and Markets ( http://www.researchandmarkets.com/research/3p32qm/access_control ) ... Market by Product, Application & By Geography - Global ... offering. , This report predicts that the ... by 2020, with an estimated CAGR of 10.6%. ... types such as contact cards & readers, contactless cards ...
(Date:3/10/2015)... March 10, 2015  Continuing its 167-year history of ... Schlemmer introduces The Eye Scanning Password Authenticator , ... access to secure websites or sensitive data. ... at international borders, the device has a small camera ... of the iris, converting them into an encrypted ID ...
Breaking Biology News(10 mins):Beta Systems Fast Forward IAM Available Now: a Standardized IAM Package at a Fixed Price 2Global Access Control (Cards & Readers, Biometrics, Controllers, Management Software) Market 2015-2020 - Analysis of the $10 Billion Market 2Hammacher Schlemmer Introduces The Eye Scanning Password Authenticator 2
(Date:3/26/2015)... March 26, 2015 WriteResult, a premier ... researchers from Yale University’s School of Public Health and ... participants during a 4 month-long project. The goal of ... low income families with free access to fresh produce ... diet-related health concerns like high blood pressure, diabetes and ...
(Date:3/25/2015)... /PRNewswire/ - SQI Diagnostics Inc. ("SQI" or the "Company") (TSX-V: ... recent discussions with certain shareholders representing approximately 45% of ... dealing with certain matters including the appointment of auditors ... March 26, 2015 (the "Meeting") it intends to adjourn ... take place when the Meeting reconvenes. The Meeting will ...
(Date:3/25/2015)...  S&P Capital IQ (MHFI) announced today that ... on Abattis Bioceuticals Corp . ... specialty biotechnology company with capabilities through its wholly ... ingredients, bio-similar compounds, patented equipment and consulting services ... . The company seeks to capitalize on ...
(Date:3/25/2015)... and REYKJAVIK, Iceland , March ... for using the genome to create better medicine, today congratulated ... largest studies of whole-genome data yet undertaken. ... Genetics – are built around the most comprehensive ... team of deCODE scientists led by Kari Stefansson , ...
Breaking Biology Technology:Yale and New Haven Farms Improving Patient Health with WriteResult's myPROpad™ 2Yale and New Haven Farms Improving Patient Health with WriteResult's myPROpad™ 3SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 2SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 3SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 4SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 5S&P Capital IQ Initiates Coverage on Abattis Bioceuticals Corp. in S&P Capital IQ Factual Stock Reports 2S&P Capital IQ Initiates Coverage on Abattis Bioceuticals Corp. in S&P Capital IQ Factual Stock Reports 3S&P Capital IQ Initiates Coverage on Abattis Bioceuticals Corp. in S&P Capital IQ Factual Stock Reports 4S&P Capital IQ Initiates Coverage on Abattis Bioceuticals Corp. in S&P Capital IQ Factual Stock Reports 5Landmark deCODE Studies Demonstrate the Power of Truly Big Genomics for Improving Medicine Worldwide 2
Cached News: