HOME >> BIOLOGY >> NEWS
Collaborative Cross to provide powerful resource for mouse model researchers worldwide

OAK RIDGE, Tenn., Sept. 22, 2005 -- A thousand new strains of mice being bred at Oak Ridge National Laboratory as part of an international effort will provide researchers with a powerful resource for studying human disease.

The project, dubbed the Collaborative Cross, has officially begun with a $1.25 million grant over five years from the Ellison Medical Foundation. When completed in about seven years, researchers worldwide will be able to fully exploit the genetic power of the mouse. Each of the estimated 1,000 strains derived from the carefully selected original eight breeds represents a resource that can be used repeatedly to accumulate data.

"Ultimately, this effort will allow us to do a much better job of modeling human populations and diseases because we will have 1,000 lines of mice that carry the kinds of genetic diversity representative of people," said Dabney Johnson, a genetics researcher in ORNL's Life Sciences Division. Johnson headed a team that wrote the proposal to the Ellison Medical Foundation.

At the heart of the project is the new $14 million Laboratory for Comparative Functional Genomics at the Department of Energy's ORNL. The pathogen-free 36,000-square-foot facility completed in 2004 boasts accommodations for 80,000 mice, cryogenic storage and other state-of-the-art features. It is at this designated DOE user facility that the breeding of the eight strains taken from around the world will be performed to initiate up to 1,500 strains of mice. Of those, researchers expect about 1,000 strains to be viable as inbreeding proceeds.

Without DOE's stewardship of the new mouse facility, the project would not be possible, said Johnson, who noted that DOE is contributing not only the space within the facility but also the technical capabilities that will allow the work to be performed.

The project, which will occupy about half of the new ORNL mouse house's capacity, is a perfect fit for ORNL, according to Johnson.
'"/>

Contact: Ron Walli
wallira@ornl.gov
865-576-0226
DOE/Oak Ridge National Laboratory
22-Sep-2005


Page: 1 2 3

Related biology news :

1. Collaborative study successfully applies neutrons to study hydrogen transfer in biological systems
2. A Cross-Disciplinary Look at Scientific Truth: Whats the Law to Do?
3. Crossing the Valley of Death: Moving science into practice and policy
4. Stem Cells: Saving Lives or Crossing Lines?
5. New study suggests Concord grape juice may provide protection against breast cancer
6. Female gender provides an advantage in renal diseases
7. Forecasting system provides flood warnings to vulnerable residents of Bangladesh
8. Discovery of new protein could provide new understanding of male fertility
9. Einstein researchers prototype vaccine could provide improved protection against tuberculosis
10. Genomics study provides insight into the evolution of unique human traits
11. Expert to provide update after worst tomato virus hits California

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/31/2016)...   LegacyXChange, Inc. ... LegacyXChange is excited to release its first ... be launched online site for trading 100% guaranteed authentic ... also provide potential shareholders a sense of the value ... industry that is notorious for fraud. The video is ...
(Date:3/22/2016)... , March 22, 2016 ... research report "Electronic Sensors Market for Consumer Industry by ... & Others), Application (Communication & IT, Entertainment, ... - Global Forecast to 2022", published by ... is expected to reach USD 26.76 Billion ...
(Date:3/17/2016)... , March 17, 2016 ABI Research, ... forecasts the global biometrics market will reach more ... 118% increase from 2015. Consumer electronics, particularly smartphones, ... fingerprint sensors anticipated to reach two billion shipments ... Dimitrios Pavlakis , Research Analyst at ABI ...
Breaking Biology News(10 mins):
(Date:4/29/2016)... , ... April 29, 2016 , ... ... necessary fundamentals to transform technology into a viable company, CereScan’s CEO, John Kelley, ... Mr. Kelley, a recognized leader and mentor in the Denver area business community, ...
(Date:4/28/2016)... YORK , April 28, 2016 ... acceleration company reports the Company,s CEO  was featured ... titled Accelerators Enter When VCs Fear To Tread: ... Science Leader magazine is an essential ... for everything from emerging biotechs to Big Pharmas. ...
(Date:4/27/2016)... ... April 27, 2016 , ... Cambridge Semantics, ... web technology, today announced that it has been named to The Silicon Review’s “20 ... services and other markets, Cambridge Semantics serves the needs of end users facing some ...
(Date:4/27/2016)... SILVER SPRING, Md. and RESEARCH ... -- United Therapeutics Corporation (NASDAQ: UTHR ) announced ... Co-Chief Executive Officer, of United Therapeutics will provide an ... Deutsche Bank 41 st Annual Health Care Conference. ... May 5, 2016, at 10:00 a.m. Eastern Time, and ...
Breaking Biology Technology:
Cached News: