HOME >> BIOLOGY >> NEWS
Common properties in the genes implicated in the development of cancer

Two researchers from the University of Navarra, Javier Novo and Jos Luis Vizmanos, have performed a bioinformatic study on the genes which have been implicated in the development of cancer. The research project has been described in an article which will be published shortly in Trends in Genetics, one of the five best journals in the area of "Genetics and Inheritance".

This bioinformatic study has permitted the researchers to identify certain common properties in those genes which are involved in the development of cancer. Dr. Novo explained that "the objective consisted in discovering whether those genes which suffer translocations (breakages) in this disease have any structural or functional characteristics in common".

Concretely, the research project performed by the two scientists of the Department of Genetics at the University of Navarra has provided, for the first time, clear data which support the hypothesis that the most important mechanisms in the development of tumors are those which generate random breakage.

"When a normal cell becomes tumorous, one of the most important changes that it experiences is that its genome becomes unstable, and breaks in various places," explained Dr. Novo. Until now, there have been many examples of this kind of breakage published, "but it was not well known what caused them nor how they were produced; for example, if they were produced at random, or if there was something in the sequence which aided in their appearance in concrete locations."

Database with Genome Regions

The authors of the article published in Trends in Genetics have constructed a data base with all the regions of the genome which break in the various types of tumors. "Over the course of several months, with the help of students from the School of Sciences, we collected from the scientific literature all the breakages which have been described in relation to cancer, we located them in the sequence
'"/>

Contact: Garazi Andonegi
garazi@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
7-Mar-2006


Page: 1 2

Related biology news :

1. Common environmental chemicals in diet affect fetal ovarian development
2. Common cancer gene sends death order to tiny killer
3. Common treatment for methamphetamine overdose may damage brain cells
4. Common genetic variation is linked to substantial risk for heart attack
5. Common fungicide causes long-term changes in mating behavior
6. DNA ends: Common tool, different job
7. Common gene version optimizes thinking -- but with a possible downside
8. Common mechanisms for viral DNA replication
9. Common ancestry of bacterium and plants could be key to an effective new treatment for chlamydia
10. Common cause of heart disease, diabetes may be treatable with malaria drug
11. Commonplace sugar compound silences seizures

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/2/2020)... ... 01, 2020 , ... AltruBio Inc. http://www.altrubio.com , a ... for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGVHD), at European Hematology Association ... of the Fred Hutchinson Cancer Research Center, this single-arm, open-label Phase 1 single ...
(Date:6/28/2020)... ... June 25, 2020 , ... In an upcoming episode scheduled for ... Point of Care Testing solutions (POCT). Check local listings for more info. , Today, ... offices and are shipped to labs throughout the country. Results are then available several ...
(Date:6/23/2020)... ... 23, 2020 , ... Rigaku Corporation , a global ... a series of TOPIQ webinars, which will cover the Transferable Aspherical Atom Model ... response to social distancing measures that resulted in postponements and cancelations of global ...
Breaking Biology News(10 mins):
(Date:7/10/2020)... ... July 09, 2020 , ... ... is commonly used to suppress pigment formation in zebrafish embryos, maintaining optical transparency ... led by Dr MA has been using the zebrafish model to investigate the ...
(Date:7/7/2020)... ... July 06, 2020 , ... Bio-IT World ... Eli Lilly, Bristol-Myers Squibb, the University of Chicago, Massachusetts General Hospital, Mission: Cure, ... an elite awards program, highlighting outstanding examples of how technology innovations and strategic ...
(Date:7/1/2020)... ... June 30, 2020 , ... ... that the launch of a new clinical diagnostics immuno-oncology service, TissueInsight ... microenvironment (TME). , “Flagship’s TissueInsight is a service that aids pathologists, oncologists, ...
(Date:6/28/2020)... Conn. (PRWEB) , ... June 25, 2020 , ... ... formed to advance photodynamic therapy for treating cancer, today announced the company has ... York (“Roswell Park”). The agreement provides Lumeda globally exclusive rights to Roswell ...
Breaking Biology Technology:
Cached News: