HOME >> BIOLOGY >> NEWS
Cornell scientists link E. coli bacteria to Crohn's disease

ITHACA, N.Y. A team of Cornell University scientists from the College of Veterinary Medicine, Weill Cornell Medical College and the College of Agriculture and Life Sciences have discovered that a novel group of E. coli bacteria containing genes similar to those described in uropathogenic and avian pathogenic E. coli and enteropathogenic bacteria such as salmonella, cholera, bubonic plague is associated with intestinal inflammation in patients with Crohns disease in their research paper published July 12 by The ISME Journal: Multidisciplinary Journal of Microbial Ecology.

Crohns disease, an incurable inflammatory disorder of the intestine most commonly found in the lower part of the small intestine called the ileum affects 1-in-1,000 people in Europe and North America. Thus far, gut bacteria have long been suspected in playing a pivotal role in the development of Crohns disease, but the specific bacterial characteristics that drive the inflammatory response have remained elusive.

Researchers at Cornell examined possible causes for the disease in patients with Crohns restricted to the ileum and the colon versus healthy individuals.

Given that only about 20 percent of fecal bacteria can be cultured, our group adopted a broad culture-independent approach to target specific subgroups of bacteria for quantitative in situ analysis and culture based characterization, said Kenneth Simpson, professor of small animal medicine at the College of Veterinary Medicine. Our findings raise the possibility that a novel group of E. coli contains opportunistic pathogens that may be causally related to chronic intestinal inflammation in susceptible individuals. They suggest that an integrated approach that considers an individuals mucosa-associated flora in addition to disease phenotype and genotype may improve outcome.

The study found an increased level of E. coli bacteria in more inflamed areas of the small intestines instead of MAP, a bacterium related
'"/>

Contact: Sabina Lee
ssl37@cornell.edu
607-255-3024
Cornell University News Service
7-Aug-2007


Page: 1 2

Related biology news :

1. Weill Cornell team identifies potential new cancer drug target
2. Methodist, University of Houston, Cornell combine biomedical imaging expertise
3. Weill Cornell pharmacologist receives prestigious NIH MERIT Award
4. Cornell lab confirms deadly fish virus spreading to new species
5. NSF awards $3.3 million grant to Cornell to bolster the percentage of women faculty members
6. Cornell researchers find serious fish virus in Northeast for first time
7. Cornell finds natural selection in humans
8. Northeast Sun Grant Institute at Cornell spurs green revolution
9. Stem cell research at Weill Cornell, The Rockefeller University, and Sloan-Kettering
10. Cornell graduate student named 2005 AIBS Emerging Public Policy Leader
11. Weill Cornell team develops fast-acting anthrax vaccine

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/13/2017)... According to a new market research report "Consumer IAM Market by ... Service, Authentication Type, Deployment Mode, Vertical, and Region - Global Forecast to ... USD 14.30 Billion in 2017 to USD 31.75 Billion by 2022, at ... ... MarketsandMarkets Logo ...
(Date:4/11/2017)... 2017 No two people are believed ... New York University Tandon School of Engineering and ... that partial similarities between prints are common enough ... phones and other electronic devices can be more ... lies in the fact that fingerprint-based authentication systems ...
(Date:4/5/2017)... Allen Institute for Cell Science today announces the launch ... dynamic digital window into the human cell. The website ... deep learning to create predictive models of cell organization, ... suite of powerful tools. The Allen Cell Explorer will ... resources created and shared by the Allen Institute for ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... partners with the pharmaceutical and biotechnology industries to improve patient outcomes and quality ... Several trends in analytical testing are being attributed to new regulatory requirements for ...
(Date:10/11/2017)... ... 11, 2017 , ... ComplianceOnline’s Medical Device Summit is back for its 4th ... in San Francisco, CA. The Summit brings together current and former FDA office bearers, ... and government officials from around the world to address key issues in device compliance, ...
(Date:10/11/2017)... ... October 11, 2017 , ... A ... pregnancy rates in frozen and fresh in vitro fertilization (IVF) transfer ... age to IVF success. , After comparing the results from the fresh and ...
(Date:10/10/2017)... ... October 10, 2017 , ... Dr. Bob Harman, founder ... local San Diego Rotary Club. The event entitled “Stem Cells and ... had 300+ attendees. Dr. Harman, DVM, MPVM was joined by two human doctors: ...
Breaking Biology Technology:
Cached News: