HOME >> BIOLOGY >> NEWS
Cracking the egg

Sexual reproduction is not necessarily sexy (especially when scientists start analyzing it), but it is fascinating. As we all know, the basics entail bringing together an egg and a sperm, a whole lot of cell division and growth, and sooner or later a young organism that carries a mix of genes from both parents. There are many startling events along the way, but one of the most fundamental and important is the transition from unfertilized egg to fertilized embryo.

Think about it: The former is and will remain an egg if left alone, while the latter has within it the means to unleash the dazzling cascade of events needed to create a viable organism. What's already in the egg that enables it to make the transition? How is it the same and how is it different across species? And what changes occur when the egg is fertilized? Scientists led by Drs Barbara Knowles and Alexei Evsikov at The Jackson Laboratory have certainly been thinking about this topic for years. A new paper in the journal Genes & Development presents significant new information about what is happening within a fully grown (pre-ovulatory) egg and some of the changes that occur during transition to the two-cell stage embryo.

The researchers performed a large-scale survey of thousands of fragments of mouse egg cDNA. The cDNA fragments are reverse coded from messenger RNA and therefore indicate which genes are being expressed. They identified 5,400 active genes in the fully grown egg, about a tenth of which are unique to egg cells. Interestingly, the process of getting ready for fertilization requires more genetic activity than early embryo development. There's a far greater diversity of RNAs in the egg cell than in the two-cell embryo, perhaps because the embryo is independent and the pre-ovulatory egg must still coordinate signals with surrounding tissues.

Another discovery was that 80% of the expressed genes identified in mouse eggs are also expressed in the eggs of two oth
'"/>

Contact: Mark Wanner
mark.wanner@jax.org
207-288-6051
Jackson Laboratory
2-Oct-2006


Page: 1 2

Related biology news :

1. Cracking open the black box of autoimmune disease
2. Cracking a virus protection shield
3. Cracking the genetic code for control of gene expression
4. Cracking the perception code
5. Cracking the olfactory code in bees

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/7/2020)... ... August 06, 2020 , ... Alucio™, a ... announce that Eric Chen and Jessica Wong have joined the company’s leadership team ... respectively. , Eric Chen heads development efforts for Alucio’s flagship product, Beacon, an ...
(Date:8/3/2020)... ... August 03, 2020 , ... Accumen Inc. is ... medical equipment manufacturer, Spectrum Solutions, to provide COVID-19 saliva testing kits nationally. ... chain for more than 10 years. Early in the COVID-19 crisis, we identified ...
(Date:7/22/2020)... SANTA BARBARA, Calif. (PRWEB) , ... July 21, ... ... consulting firm driving digital transformation and innovation in technology and compliance, announces a ... and medical device companies must ensure every layer of their technology stack complies ...
Breaking Biology News(10 mins):
(Date:9/1/2020)... ... 01, 2020 , ... Slone Partners , a nationwide ... placement of Julianne Averill , CPA, as Chief Financial Officer at ... implementing key business strategies to accelerate Alveo’s growth as the company advances its ...
(Date:8/12/2020)... , ... August 11, 2020 ... ... biopharmaceutical cold chain validation engineering firm, is making available for free its ... need to incorporate concurrent transport simulation testing into today’s biologics licensing application ...
(Date:7/31/2020)... ... July 29, 2020 , ... R3 Stem Cell International is now offering patients ... million stem cells total, patients may choose which extremities they would like treated. , ... (BMC Musculoskelet Disord. 2016). At R3 International, umbilical cord tissue is obtained from a ...
(Date:7/31/2020)... ... July 29, 2020 , ... eSource has long been touted as the ... the history of eSource, the reasons it did not take off as quickly as ... source, the industry is moving towards capturing data electronically for clinical trials and then ...
Breaking Biology Technology:
Cached News: