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Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism

time, the study shows that one of these proteins is very important because of its ability to activate cells of the innate immune system involved in the initial phases of the disease.

This new study therefore confirms that antibodies directed against Cytomegalovirus-derived proteins purified from patients with coronary artery disease induce endothelial cells damage and support the hypothesis that virus infection plays a crucial role in mediating the atherosclerotic process. Moreover, these findings contribute to the design of novel preventive and therapeutic strategies.


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Contact: Claudio Lunardi
claudio.lunardi@univr.it
Public Library of Science
29-May-2007


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