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DNA gets new twist: Carnegie Mellon scientists develop unique 'DNA nanotags'

or even infrared light. Changing the light-harvesting dyes allows even more variation in the fluorescence color, Armitage said.

The nanotags are easily assembled by mixing commercially available DNA strands and fluorescent dyes. And while the work described by the Carnegie Mellon team relied on a relatively simple two-dimensional DNA nanostructure, Armitage notes that the rapidly growing field of DNA nanotechnology is generating increasingly intricate three-dimensional nanostructures that should lead to further improvements in brightness.

"We really feel that this is the tip of the iceberg and that nanotags 100 times brighter than existing labels can be developed in any color," he said.


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Contact: Lauren Ward
wardle@andrew.cmu.edu
412-268-7761
Carnegie Mellon University
26-Jan-2007


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