The technical challenges presented by GTL analyses and the scale of the systems that must be understood -- from genomes to ecosystems -- exceed current capabilities. To meet these analytical needs, DOE has proposed four large research and production facilities for rapidly unraveling the tremendous complexity of biological systems. These world-class resources would be available to the broader research community as well as industry and would dramatically increase the pace of discovery. Such advances will enable rapid translation of science into new technologies, ultimately shortening the path to national benefits. The GTL facilities are among those featured in the DOE Office of Science's 20-year facilities plan (Facilities for the Future of Science: A Twenty-Year Outlook, 2003).
The 2005 GTL Roadmap builds on and expands the GTL research program begun in 2002. Scientific and technological progress achieved during the Human Genome Project, initiated in 1986 by DOE, and the Microbial Genome Program, begun in 1994, provided the foundation for establishing the GTL program. The roadmap may be viewed at www.sc.doe.gov. For more information on the GTL program visit: www.DOEGenomesToLife.org