Thomas M. Huckaba, PhD, with his sponsor Ronald D. Vale, PhD, at the University of California, San Francisco, California, is defining the way in which the organization of the cellular scaffold impacts cancer cell spread or metastasis.

Melissa R. Junttila, PhD, with her sponsor Gerard I. Evan, PhD, at the University of California, San Francisco, California, is designing new mouse models to challenge long standing dogma about how p53, the most commonly mutated gene in human cancer, contributes to tumor formation and aging processes.

Lszl Krti, PhD, with his sponsor Elias James Corey, PhD, at Harvard University, Cambridge, Massachusetts, is devising a chemical synthesis strategy for the natural compound Cortistatin A, a novel anti-cancer drug that targets metastatic disease.

David S. Matus, PhD, with his sponsor David R. Sherwood, PhD, at Duke University, Durham, North Carolina, is using a powerful genetic model to identify the gene networks that control cell invasion a critical step in understanding how cancer cells spread.

Yunsun Nam, PhD, with her sponsor Tom A. Rapoport, PhD, at Harvard Medical School, Boston, Massachusetts, is determining how protein molecules are transported into and out of the cell a fundamental question with potential impact in the areas of carcinogenesis, drug transport, and drug discovery.

Cara T. Pager, PhD, with her sponsor Peter Sarnow, PhD, at Stanford University, Stanford, California, is deciphering the role of newly discovered small RNAs in the regulation of the hepatitis C virus, a novel approach with implications for liver cancer antiviral therapies.

Katharina Schlacher, PhD, with her sponsor Maria Jasin, PhD, at the Memorial Sloan-Kettering Cancer Center, New York, New York, is defining DNA repair mechanisms that contribute to breast and ovarian cancers.

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Contact: Jennifer McCafferty-Cepero
jennifer.mccafferty@drcrf.org
212-455-0520
Damon Runyon Cancer Research Foundation
27-Jun-2007