HOME >> BIOLOGY >> NEWS
Data presented at ISHLT meeting confirm RNA analysis can identify rejection in lung transplant recip

ve blood tests that determine a patient's gene expression profile, can identify those genes that are expressed during the rejection of a lung," said Dr. Keshavjee. "The data being presented at this year's ISHLT meeting shows the potential that exists to develop a non-invasive test that could alleviate the need for tens of thousands of biopsies."

Currently, uncomfortable and invasive biopsies are the standard for monitoring lung transplant recipients for acute cellular rejection. Biopsies are performed frequently in the first year post-transplant and periodically thereafter, often for the patient's lifetime.

Current data shows that 1,400 lung transplants were performed in 2006. And in recent years, approximately 83.3 percent of lung transplant patients survived one year following the transplant, while 62.8 percent survived three years and 47.3 survived five years. Transplant rejection is a primary concern for long-term survival, both immediately after surgery and through the patient's lifetime. To prevent rejection and subsequent damage to the new lungs, patients must take a lifelong regimen of immunosuppressive drugs.

About the LARGO Study

The LARGO study was initiated in April 2004 to examine the utility of molecular testing in post-transplant lung patient management. Fourteen centers from five countries and two continents are participating in this study to investigate the utility of gene expression testing for management of lung transplant recipients.

Several thousand samples have been collected in the LARGO database. The LARGO study and database provide an unparalleled resource for genomic and molecular diagnostic studies and development in lung transplantation.

The studies presented at ISHLT were sponsored by XDx, whose laboratory provides the gene expression testing service used in the investigation.


'"/>

Contact: Margaret Clark
mclark@masonpr.com
210-857-2521
International Society for Heart and Lung Transplantation
27-Apr-2007


Page: 1 2

Related biology news :

1. Clinical trial data regarding NKTR-061 will be presented at ATS International Conference
2. Latest plant health research to be presented in San Diego
3. Presidential Recognition Awards presented at the 2007 AIUM Annual Convention
4. Soliris (eculizumab) data to be presented at American Society of Hematology
5. Agronomy, crop, soils research presented in Indianapolis
6. UW-Madison work on stem cells, cardiac health to be presented at ACS
7. Weizmann Women & Science Award presented to Dr. Mary-Claire King
8. IOF-Novartis Young Scholars Awards presented to seven researchers from six countries
9. Coma misrepresented in movies
10. Latest plant disease research to be presented in Quebec City
11. AIUM Presidential Recognition Awards presented

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/30/2020)... Calif. (PRWEB) , ... May 29, 2020 , ... ... enabler of digital transformation for enterprises globally, has collaborated with EchoNous Inc. to ... FDA. It can measure systolic heart function, which has been clinically tested ...
(Date:5/28/2020)... ... 2020 , ... Today bioinformatics leader hc1® announced ... lab testing insights and hc1’s exclusive Local Risk Index in a unified CV19 ... employees returning to the workplace. , “Some of the best ways to keep ...
(Date:5/28/2020)... FORT WORTH, Texas (PRWEB) , ... May 28, ... ... biopharmaceutical company, announced today that interim results from their 1801 Phase 1/2 study ... Clinical Oncology (ASCO) Annual Meeting which will take place virtually on May 29th, ...
Breaking Biology News(10 mins):
(Date:5/5/2020)... TAMPA, Fla. (PRWEB) , ... May 05, 2020 ... ... technology and solutions company, announced today the launch of its iGlucose® ... The new iGlucose solution utilizes LTE Cat-M1 technology, the industry’s newest and broadest ...
(Date:4/22/2020)... ... April 20, 2020 , ... Global ... announced today that Omixon’s founder and chairman Dr. Attila Berces returns as CEO. ... Holotype HLA since 2014 before stepping into the CEO role in 2017. ...
(Date:4/7/2020)... ... 2020 , ... Gateway Genomics , leading developer of direct-to-consumer genetic tests ... DNA Tests sold in March, just months after attaining the 150,000-test landmark in ... a mom could order her kit online, collect a DNA sample from her home, ...
(Date:4/1/2020)... ... March 31, 2020 , ... ... developed a method using its revolutionary NEXTGENPCR endpoint thermocycler and consumables that ... reaction volumes, increased samples per run, and standard, affordable laboratory equipment, a ...
Breaking Biology Technology:
Cached News: