HOME >> BIOLOGY >> NEWS
Decision-making -- Demonstration of a link between cognition and execution

he decision-making phase and the executive phase.

To establish this interaction, researchers in the Movement, Adaptation, Cognition Laboratory, a joint CNRS and University of Bordeaux 2 unit affiliated to the Franco-Israeli Neurophysiology and Neurophysics of Systems Laboratory , simultaneously recorded in primates the electrical activity of neurons in the two structures concerned, the striatum and internal globus pallidus. The animals were required to choose between two targets which were rewarded differently, and then perform a movement towards the target chosen. It had previously been determined that each animal had learnt to associate each target with a different probability of obtaining a reward. They therefore had to have memorised these combinations and chosen the target associated with the greatest probability of an optimum reward.

This experiment showed that cognitive information modulates the coding of motor information via neurons which belong to the two key structures in the basal ganglia: at entry and exit. This is the first time that a cellular interaction has been demonstrated between purely cognitive and purely motor information. Above all, the mechanisms by which the basal ganglia integrate these two types of information have been elucidated. This discovery will have a considerable impact on our knowledge of Parkinson's disease, as this condition is caused by a degeneration of dopamine-producing neurons. As a result, it will be necessary to adopt a new approach to this disease. Although Parkinson's disease expresses itself through severely incapacitating motor disorders, such as an increasing difficulty in initiating and executing movements, marked muscle rigidity and tremor, it should no longer be considered as a purely motor pathology: it will now be necessary to take account of its cognitive dimension as well.


'"/>

Contact: Monica McCarthy
monica.mccarthy@cnrs-dir.fr
33-144-965-191
CNRS
8-Feb-2007


Page: 1 2

Related biology news :

1. New textbook illuminates the close links between evolutionary and molecular biology
2. Link between sunspots, rain helps predict disease in east Africa
3. Link identified between Alzheimers disease and glaucoma
4. Teamwork between 2 key proteins necessary for normal development and regulation of red blood cells
5. Human knowledge is based upon directed connectivity between brain areas
6. First case of successful ovarian tissue transplantation between two, nonidentical sisters
7. Strength of connections between brain regions may affect an adolescents response to peer influence
8. MIT IDs link between brain tumor proteins
9. Co-operation between GSF and clinic improves outlook for sarcoma patients
10. FDA finds no strong link between tomatoes and reduced cancer risk
11. Link between immune system and mammary gland could shed new light on breast cancer

Post Your Comments:
(Date:11/6/2014)... deaths occur because of metastasis, yet progress in ... slow. , "It,s been particularly challenging to design ... research fellow in systems biology at Harvard Medical ... until after they,ve already metastasized." , Gujral and ... should help researchers better understand how metastasis begins. ...
(Date:11/6/2014)... 2014 - Insilico Medicine, Inc, a Baltimore-based bioinformatics ... related diseases announced a research collaboration with the ... Oncology, Inc (OTC: CSBR). , "There are many ... but Champions Oncology,s TumorGraft technology is unique in ... regimen experimentally generating vast amounts of valuable data. ...
(Date:11/5/2014)... dedicated his career to understanding the Earth,s climate ... , As deputy director and regional climatologist for ... Research Institute, Redmond has more than three decades ... of climate data to the general public. , ... Francisco on December 15-19, 2014 the American Geophysical ...
Breaking Biology News(10 mins):Migration negation 2Migration negation 3Insilico Medicine, Inc announces research collaboration with Champions Oncology, Inc 2Nevada climatologist to be honored at AGU Fall Meeting for lifetime of public outreach 2
(Date:11/27/2014)... DUBLIN , Nov. 27, 2014 ... of the "Global Palmitic Acid Industry Report 2014" ... http://photos.prnewswire.com/prnh/20130307/600769 The Global Palmitic Acid ... on the current state of the global palmitic acid ... of the industry including definitions, classifications, applications and industry ...
(Date:11/26/2014)... NOVEMBER 21, 2014 (PRWEB) November 26, 2014 ... health-oriented communications network, today announced the organization has won ... Rx Club Awards. Digitas Health LifeBrands was honored with ... four other PHCG agencies received eight Awards of Excellence. ... creative aspects of pharmaceutical advertising and promotion. The Awards ...
(Date:11/26/2014)... YORK , Nov. 26, 2014 The ... may indicate the company is looking to expand in ... further sales.  The healthcare market research firm says that  ... to Kalorama Information,s biennial survey of the IVD market ... and any change in its composition would likely affect ...
(Date:11/26/2014)... PMG Research, Inc. announced today the formation ... of sites that provide clinical research services to pharmaceutical companies ... through its partnerships with large physician practices and integrated health ... in the Southeastern United States and spans over 60 physician ... will be held by: Dr. Robert Holmes, MD, of ...
Breaking Biology Technology:Global Palmitic Acid Industry Report 2014 2Publicis Healthcare Wins 20 Rx Club Awards 2Publicis Healthcare Wins 20 Rx Club Awards 3Kalorama: Sale of Three Siemens Healthcare Units Raises Questions About Firm's IVD Future 2PMG Research Names Medical Advisory Board 2PMG Research Names Medical Advisory Board 3
Cached News: