HOME >> BIOLOGY >> NEWS
Decision-making -- Demonstration of a link between cognition and execution

he decision-making phase and the executive phase.

To establish this interaction, researchers in the Movement, Adaptation, Cognition Laboratory, a joint CNRS and University of Bordeaux 2 unit affiliated to the Franco-Israeli Neurophysiology and Neurophysics of Systems Laboratory , simultaneously recorded in primates the electrical activity of neurons in the two structures concerned, the striatum and internal globus pallidus. The animals were required to choose between two targets which were rewarded differently, and then perform a movement towards the target chosen. It had previously been determined that each animal had learnt to associate each target with a different probability of obtaining a reward. They therefore had to have memorised these combinations and chosen the target associated with the greatest probability of an optimum reward.

This experiment showed that cognitive information modulates the coding of motor information via neurons which belong to the two key structures in the basal ganglia: at entry and exit. This is the first time that a cellular interaction has been demonstrated between purely cognitive and purely motor information. Above all, the mechanisms by which the basal ganglia integrate these two types of information have been elucidated. This discovery will have a considerable impact on our knowledge of Parkinson's disease, as this condition is caused by a degeneration of dopamine-producing neurons. As a result, it will be necessary to adopt a new approach to this disease. Although Parkinson's disease expresses itself through severely incapacitating motor disorders, such as an increasing difficulty in initiating and executing movements, marked muscle rigidity and tremor, it should no longer be considered as a purely motor pathology: it will now be necessary to take account of its cognitive dimension as well.


'"/>

Contact: Monica McCarthy
monica.mccarthy@cnrs-dir.fr
33-144-965-191
CNRS
8-Feb-2007


Page: 1 2

Related biology news :

1. New textbook illuminates the close links between evolutionary and molecular biology
2. Link between sunspots, rain helps predict disease in east Africa
3. Link identified between Alzheimers disease and glaucoma
4. Teamwork between 2 key proteins necessary for normal development and regulation of red blood cells
5. Human knowledge is based upon directed connectivity between brain areas
6. First case of successful ovarian tissue transplantation between two, nonidentical sisters
7. Strength of connections between brain regions may affect an adolescents response to peer influence
8. MIT IDs link between brain tumor proteins
9. Co-operation between GSF and clinic improves outlook for sarcoma patients
10. FDA finds no strong link between tomatoes and reduced cancer risk
11. Link between immune system and mammary gland could shed new light on breast cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/28/2017)... , March 28, 2017 The ... Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, ... Region - Global Forecast to 2022", published by MarketsandMarkets, ... 2016 and is projected to reach USD 75.64 Billion ... and 2022. The base year considered for the study ...
(Date:3/24/2017)... 24, 2017 The Controller General of Immigration from ... Abdulla Algeen have received the prestigious international IAIR Award for the ... Continue Reading ... ... Controller Abdulla Algeen (small picture on the right) have received the IAIR ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based ... to 2022", published by MarketsandMarkets, the market is expected to be worth USD ... 2022. Continue Reading ... ... ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , Oct. ... Cancer Research, London (ICR) and University ... SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple myeloma ... MUK nine . The University of Leeds ... partly funded by Myeloma UK, and ICR will perform the ...
(Date:10/10/2017)... ... 2017 , ... San Diego-based team building and cooking events company, Lajollacooks4u, has ... The bold new look is part of a transformation to increase awareness, appeal to ... period. , It will also expand its service offering from its signature gourmet cooking ...
(Date:10/10/2017)... 10, 2017 International research firm Parks Associates announced ... at the TMA 2017 Annual Meeting , October 11 in ... residential home security market and how smart safety and security products impact ... Parks Associates: Smart Home ... "The residential security market has ...
(Date:10/9/2017)... DIEGO , Oct. 9, 2017  BioTech ... biological mechanism by which its ProCell stem cell ... critical limb ischemia.  The Company, demonstrated that treatment ... amount of limbs saved as compared to standard ... the molecule HGF resulted in reduction of therapeutic ...
Breaking Biology Technology:
Cached News: