HOME >> BIOLOGY >> NEWS
Decision-making -- Demonstration of a link between cognition and execution

he decision-making phase and the executive phase.

To establish this interaction, researchers in the Movement, Adaptation, Cognition Laboratory, a joint CNRS and University of Bordeaux 2 unit affiliated to the Franco-Israeli Neurophysiology and Neurophysics of Systems Laboratory , simultaneously recorded in primates the electrical activity of neurons in the two structures concerned, the striatum and internal globus pallidus. The animals were required to choose between two targets which were rewarded differently, and then perform a movement towards the target chosen. It had previously been determined that each animal had learnt to associate each target with a different probability of obtaining a reward. They therefore had to have memorised these combinations and chosen the target associated with the greatest probability of an optimum reward.

This experiment showed that cognitive information modulates the coding of motor information via neurons which belong to the two key structures in the basal ganglia: at entry and exit. This is the first time that a cellular interaction has been demonstrated between purely cognitive and purely motor information. Above all, the mechanisms by which the basal ganglia integrate these two types of information have been elucidated. This discovery will have a considerable impact on our knowledge of Parkinson's disease, as this condition is caused by a degeneration of dopamine-producing neurons. As a result, it will be necessary to adopt a new approach to this disease. Although Parkinson's disease expresses itself through severely incapacitating motor disorders, such as an increasing difficulty in initiating and executing movements, marked muscle rigidity and tremor, it should no longer be considered as a purely motor pathology: it will now be necessary to take account of its cognitive dimension as well.


'"/>

Contact: Monica McCarthy
monica.mccarthy@cnrs-dir.fr
33-144-965-191
CNRS
8-Feb-2007


Page: 1 2

Related biology news :

1. New textbook illuminates the close links between evolutionary and molecular biology
2. Link between sunspots, rain helps predict disease in east Africa
3. Link identified between Alzheimers disease and glaucoma
4. Teamwork between 2 key proteins necessary for normal development and regulation of red blood cells
5. Human knowledge is based upon directed connectivity between brain areas
6. First case of successful ovarian tissue transplantation between two, nonidentical sisters
7. Strength of connections between brain regions may affect an adolescents response to peer influence
8. MIT IDs link between brain tumor proteins
9. Co-operation between GSF and clinic improves outlook for sarcoma patients
10. FDA finds no strong link between tomatoes and reduced cancer risk
11. Link between immune system and mammary gland could shed new light on breast cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/1/2016)... , June 1, 2016 ... in Election Administration and Criminal Identification to Boost Global ... a recently released TechSci Research report, " Global Biometrics ... Region, Competition Forecast and Opportunities, 2011 - 2021", the ... billion by 2021, on account of growing security concerns ...
(Date:5/16/2016)... YORK , May 16, 2016   EyeLock ... solutions, today announced the opening of an IoT Center ... to strengthen and expand the development of embedded iris ... an unprecedented level of convenience and security with unmatched ... authenticate one,s identity aside from DNA. EyeLock,s platform uses ...
(Date:5/3/2016)...  Neurotechnology, a provider of high-precision biometric identification ... Identification System (ABIS) , a complete system for ... can process multiple complex biometric transactions with high ... face or iris biometrics. It leverages the core ... MegaMatcher Accelerator , which have been used in ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... June 27, 2016 , ... Newly created ... and solutions to the healthcare market. The company's primary focus is on new ... and marketing strategies that are necessary to help companies efficiently bring their products ...
(Date:6/24/2016)... , June 24, 2016 Epic Sciences ... detects cancers susceptible to PARP inhibitors by targeting ... cells (CTCs). The new test has already been ... in multiple cancer types. Over 230 ... damage response pathways, including PARP, ATM, ATR, DNA-PK ...
(Date:6/23/2016)... Mass. , June 23, 2016   ... development of novel compounds designed to target cancer ... napabucasin, has been granted Orphan Drug Designation from ... the treatment of gastric cancer, including gastroesophageal junction ... stemness inhibitor designed to inhibit cancer stemness pathways ...
(Date:6/23/2016)... , June 23, 2016  The Prostate Cancer Foundation (PCF) ... precise treatments and faster cures for prostate cancer. Members of the Class of ... 15 countries. Read More About the Class of 2016 ... ... ...
Breaking Biology Technology:
Cached News: