HOME >> BIOLOGY >> NEWS
Developing radiotracers for imaging studies in addiction

SAN FRANCISCO, CA - Molecular imaging using positron emission tomography (PET) continues to provide new knowledge about how brain circuits are altered by addictive drugs. Chemist Joanna Fowler, Director of the Center for Translational Neuroimaging at the U.S. Department of Energy's Brookhaven National Laboratory and a pioneer in the development of radioactively "tagged" molecules used with PET, will give a talk on these radiotracers at the 232nd national meeting of the American Chemical Society in San Francisco, California, at 8:25 a.m. Pacific Time on Thursday, September 14, 2006, in Room 270 of the Moscone Convention Center.

"Addiction is a brain disease that is devastating for families and society," said Fowler. "Chemistry -- through the development of radiotracers that can monitor the distribution and kinetics of drugs and receptors in the brain -- is at the core of understanding the addictive process and finding new ways to help people overcome it."

In PET studies, radiotracers (compounds labeled with a radioactive form of certain chemical elements such as carbon or fluorine) are injected into a research subject's bloodstream. A PET scanner picks up the radioactive signal from the tracer and continuously tracks its concentration and movement through the body. The data can be used to reconstruct three-dimensional images that reveal where the compound goes in the body/brain and how long it stays, for example.

The Brookhaven group, led by Fowler, has developed radiotracers to track the movement of various addictive drugs including cocaine, nicotine, and methamphetamine, and also to measure the levels of certain "chemical messengers," or neurotransmitters, and their receptors in the brain. PET studies using these radiotracers have revealed, for example, that all addictive drugs elevate levels of a neurotransmitter called dopamine, a chemical that helps us experience feelings of pleasure, reward, and motivation -- and also plays a ro
'"/>

Contact: Kay Cordtz
kcordtz@bnl.gov
631-344-2719
DOE/Brookhaven National Laboratory
14-Sep-2006


Page: 1 2 3 4

Related biology news :

1. Developing a more effective vaccine for tuberculosis
2. Using Nanotechnology to Improve Health Care in Developing Countries
3. AAAS/EurekAlert! refocus on China with 2007 Fellowships for Science Reporters in Developing Regions
4. Developing uses for sugar-cane bagasse: Biotechnology applied to the paper industry
5. Developing countries take the lead in a global program to catalogue human mutations
6. Developing nations may save the tropical forest
7. AAAS and EurekAlert! announce winners of the 2006 Fellowships for Reporters from Developing Regions
8. Developing nervous system sculpted by opposing chemical messengers
9. New imaging method clarifies nutrient cycle
10. Methodist, University of Houston, Cornell combine biomedical imaging expertise
11. 2007 Image of the Year: Molecular imaging relates human brain chemistry to aggressive behavior

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/2/2020)... CITY, Calif. (PRWEB) , ... July 01, 2020 ... ... biotech company, presented its phase 1a findings of Neihulizumab, a biologic for the ... conference in June 2020. Led by hemato-oncologist Dr. Paul J Martin of the ...
(Date:7/1/2020)... , ... July 01, 2020 , ... ... awareness and solutions for glioblastoma—the most common and aggressive adult brain cancer—announced today ... JD, PhD. Senior Fellows are charged with supporting the organization’s initiatives and overall ...
(Date:6/25/2020)... ... June 24, 2020 , ... eClinical Solutions ... data services that accelerate drug development, is collaborating with Karyopharm Therapeutics (Nasdaq: ... hospitalized patients with severe COVID-19. This is the first study of an XPO1 ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... July 29, 2020 , ... R3 Stem Cell International ... only $3950. With 50 million stem cells total, patients may choose which extremities they ... works for arthritic joints (BMC Musculoskelet Disord. 2016). At R3 International, umbilical cord tissue ...
(Date:7/31/2020)... ... July 29, 2020 , ... Anomet Products has ... different materials for use with CRM, neurostimulation, vascular, and related devices. , ... specific design requirements, performance, and cost criteria; especially where solid wire is limited. ...
(Date:7/31/2020)... ... July 29, 2020 , ... The SDX® ... in 16 countries, has reached its 20th anniversary of worldwide use. Introduced in ... at top universities including University of Pennsylvania, University of Michigan, University of Maryland, ...
(Date:7/18/2020)... TORONTO (PRWEB) , ... July 16, 2020 , ... After ... begins. The completion of a great surgery is only the beginning of a successful ... the research community. , Join Brad Gien, Global Head of Surgery from Envigo ...
Breaking Biology Technology:
Cached News: