Does cancer run in families?

If you have a relative with cancer, probably one of the most pressing questions is what your chances are of getting it yourself. In a paper published in PloS Medicine, the premier medical journal freely available online, Laufey Amundadottir and colleagues from deCODE genetics (a company that is using genetics to develop new drug treatments) and Iceland's National-University Hospital go some way toward answering that question. They analyzed comprehensive data on the most common forms of cancer from Iceland's National Cancer Registry in the context of deCODE's nationwide genealogy database. This enabled Dr. Amundadottir and her team to establish how often cancers occurred in first through fifth degree relatives of some 32,000 cancer patients over the past 50 years.

For 16 of the 27 cancers studied, the results indicate that relatives of patients are at a significantly higher risk of developing cancer than are members of the population at large. For some cancers this increased risk even extended out to distant (i.e. 3rd to 5th degree) relatives. Cancers in certain sites also showed a familial association with other cancers--for example relatives of individuals with stomach, colon, rectal, or endometrial cancer were more likely to develop one of these cancers, although not necessarily in the same site as did their relative. Three cancers--stomach, lung and colon cancer--were also seen more frequently in the mates of patients, confirming that shared lifestyle or environmental factors such as smoking, diet or exercise habits also contribute substantially to the increased risk.

The seven cancers with the highest increased familial occurrence both in close and distant relatives were breast, prostate, stomach, lung, colon, kidney and bladder cancers. However, even for these cancers the increased relative risk for first-degree relatives was generally less than twice that for the population at large, and this risk diminished significantly for

Contact: Paul Ocampo
Public Library of Science

Page: 1 2

Related biology news :

1. Protein chatter linked to cancer activation
2. Newly created cancer stem cells could aid breast cancer research
3. Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
4. ESF EURYI award winner aims to stop cancer cells reading their own DNA
5. No evidence that widely prescribed statins protect against prostate cancer
6. A study by the MUHC and McGill University opens a new door to understanding cancer
7. New study suggests Concord grape juice may provide protection against breast cancer
8. New test improves detection of liver cancer
9. High-intensity ultrasound may launch attack on cancer, wherever it lurks
10. Unknotting DNA clue to cancer syndrome
11. Biologists at Tufts University discover 1 reason why chromosomes break, often leading to cancer

Post Your Comments:

(Date:8/12/2020)... , ... August 12, 2020 , ... ... monitoring systems that are ideal for public health agencies of all sizes. With ... diseases and helping at-risk individuals find appropriate health care, Mosio helps public health ...
(Date:8/5/2020)... ... August 05, 2020 , ... Regenative Labs has received ... innovations, CoreText™ and ProText™, making them the first Wharton’s jelly allografts to be assigned ... syringe. The company’s solutions are the first Wharton’s jelly allograft product to be recognized ...
(Date:7/31/2020)... ... July 30, 2020 , ... ... product portfolio with a near term focus on Type 2 diabetes and associated ... experience across multiple therapeutic areas and classes. As Chief Commercial Officer, Justin will ...
Breaking Biology News(10 mins):
(Date:8/12/2020)... BINGHAM FARMS, Mich. (PRWEB) , ... August 12, ... ... International Consulting Group, Inc. (EMMA International), a global leader in FDA compliance ... ranking of the nation’s fastest-growing private companies. The list represents a unique look ...
(Date:8/3/2020)... ... 03, 2020 , ... Introducing Ardent Animal Health – MediVet Biologics rebrands company ... Known as MediVet Biologics since its formation in 2016, the company is relaunching ... Health will build on its base of innovative therapies for osteoarthritis and cancer. ...
(Date:7/31/2020)... ... 2020 , ... Diversified Technologies, Inc. has introduced a full ... drive Klystrons, TWTs, IOTs, and magnetrons. , DTI Radar Transmitter Systems ... push-pull configuration; yielding fast fall time for a capacitive load. These all solid-state ...
(Date:7/31/2020)... ... ... eSource has long been touted as the solution to high data management and ... it did not take off as quickly as people initially expected, and where eSource ... capturing data electronically for clinical trials and then repurposing it for downstream analysis, at ...
Breaking Biology Technology:
Cached News: