HOME >> BIOLOGY >> NEWS
Drugs from the deep blue

For Tadeusz Molinski, the sea is full of riches -- and he does not mean oil fields or fisheries. Molinski, a professor of chemistry at the University of California, Davis, is searching for new treatments for cancer, infectious diseases and other conditions that could be made from natural products in the soft bodies of some of the ocean's simplest inhabitants.

"Three quarters of the world is covered by oceans, and we've only dipped below the surface," Molinski said.

This chemist sees natural products from marine organisms as an opportunity to answer questions in biology and find potential leads for the next generation of drugs, whether those are anti-fungals or treatments for cancer. Many pharmaceutical drugs on the market, from aspirin to cholesterol-lowering "statins," are derived from natural products such as plants or bacteria. Molinski says modern developments in analytical chemistry, including highly sensitive instrumentation, sophisticated screening capabilities and discoveries from mapping the human genome, have created a renaissance of interest in these sources of potential medicines.

Molinski's laboratory studies the chemistry and biology of marine natural products, or chemical compounds made by sea creatures. It is part of a developing focus on pharmaceutical chemistry within the UC Davis chemistry department, including research on biologically active molecules and high-throughput screening techniques.

Most of Molinski's samples come from sponges and tunicates, marine creatures that can neither swim away from a diver nor bite. Recently, the researchers have also begun to collect samples from cyanobacteria, single-celled organisms that occur as slimy mats or filaments in places such as coral reefs and mangrove lagoons.

Some of these compounds have biochemical activities that could be useful in medicine -- killing microbes, stopping growth of cancer cells, or affecting the flow of calcium in and out of cells.

Mari
'"/>

Contact: Andy Fell
ahfell@ucdavis.edu
530 752-4533
University of California - Davis
1-Jun-2005


Page: 1 2 3 4

Related biology news :

1. Eleven million Euros for Endotrack
2. Molecular signature protects cells from viruses
3. Novel molecular signature marks DNA of embryonic stem cells
4. Common molecular signature identified in solid tumors
5. Gene predicts better outcome as cortex normalizes in teens with ADHD
6. Marker predicts pancreatic cancer outcome after surgery, Jefferson surgeon finds
7. Major study predicts grim future for Europes seas
8. FDG-PET imaging clearly predicts lung cancer patients response to chemotherapy
9. NASA predicts nongreen plants on other planets
10. Gene profiling predicts resistance to breast cancer drug Herceptin
11. Mathematical model predicts cholera outbreaks

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/7/2019)... ... January 07, 2019 , ... Franz ... Graph Database technology for Knowledge Graphs solutions, announced that it was recognized by ... . DBTA’s data and information management recognition list includes newer approaches leveraging ...
(Date:12/27/2018)... BOSTON (PRWEB) , ... December 27, 2018 , ... ... first 60 cervical discs for implantation at its new Boston facility, and is ... to have additional inventory to immediately expand market share against inferior ball and ...
(Date:12/19/2018)... ... 2018 , ... NDA Partners Chairman Carl Peck, MD, announced today that ... for Devices and Radiological Health (CDRH), has been appointed a Partner in the firm. ... she has more than 25 years of regulatory experience. In addition to her FDA ...
Breaking Biology News(10 mins):
(Date:1/10/2019)... Fla. (PRWEB) , ... January ... ... Geometrical Implant Co, (SAGICO), an innovative spinal implant company, announced today that ... in San Francisco, California. The annual J.P. Morgan Healthcare Conference is ...
(Date:1/4/2019)... ... January 04, 2019 , ... ... Ted Hoffman to the firm. Ted will be joining the firm as a ... and providing consulting services to the pharmaceutical industry. At Triangle Insights, Ted will ...
(Date:12/19/2018)... ... December 19, 2018 , ... R3 Stem Cell is ... Training Course in Las Vegas. Training includes facial rejuvenation, hair restoration and erectile ... nationwide for aesthetics, having the training from expert, Board Certified providers is critical ...
(Date:12/14/2018)... ... December 14, 2018 , ... NOVA OCULUS ... given the green light to immediately begin a clinical patient trial in Edmonton ... devices bureau of Health Canada has granted what is called an Investigational Testing ...
Breaking Biology Technology:
Cached News: