HOME >> BIOLOGY >> NEWS
EPA-led group finds same protein that attracts nutrient iron protects lung from particles

So what's DMT1 doing in the liver, kidneys and brain?

BETHESDA, Md. (Oct. 3, 2005) Multi-vitamin products, nutritional supplements and parents tout the need for such mineral elements as calcium, zinc, phosphorus, iron and others.

Iron, for example, is a nutritional prerequisite to power life itself. When blood doesn't get enough iron from the gut, we become anemic. One of the body's coping mechanisms is to produce more of a protein called divalent metal transporter 1 (DMT1) in the gastrointestinal lining cells to bring into the body as much iron as possible. Until recently DMT1 was exclusively studied for its nutritional role in transporting iron.

But put iron or other air-borne particulates into our lungs and they can cause health problems ranging from asthma and acute respiratory distress syndrome to asbestosis and lung cancer.

In a recently-published paper a group of EPA-led lung researchers reported experiments demonstrating for the first time that "DMT1 is essential for the transport and detoxification of some metals associated with an air pollution particle that damages the pulmonary epithelial surface."

The paper "Divalent metal transporter-1 decreases metal-related injury in the lung" appears in the American Journal of Physiology-Lung Cellular and Molecular Physiology, published by the American Physiological Society. Research was performed by Andrew J. Ghio, Lisa A. Dailey, Jacqueline D. Stonehuerner and Michael C. Madden from the U.S. Environmental Protection Agency; Claude A. Piantadosi of Duke University; Xinchao Wang of University of North Carolina; Funmei Yang of University of Texas; and Kevin G. Dolan, Michael D. Garrick and Laura M. Garrick of SUNY-Buffalo.

Lead researcher Andrew Ghio said this breakthrough discovery of DMT1 lung protection could prompt studies of its roles in other organs where it's found. "For instance, DMT1 is in the liver, kidneys and brain, where it's not needed f
'"/>


3-Oct-2005


Page: 1 2 3 4

Related biology news :

1. Neurons for numerosity: Parietal neurons sum up individual items in a group
2. Johns Hopkins Bloomberg School of Public Health, Geisinger launch new environmental research group
3. Research group gets $7 million to pursue new antibiotic agents
4. Gene study shows three distinct groups of chimpanzees
5. No sign that ethnic groups genes cause diabetes, international research team says
6. Fisheries group calls for science-based approach to address climate impacts
7. 20 of worlds 162 grouper species threatened with extinction
8. Genes and groups of genes commonly shared between species, studies show
9. New group of algae discovered: Picobiliphytes
10. The case of the snuggling skunks -- Is it better to brave winter alone or in a group?
11. 1st international study group for new movement discipline

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/15/2016)... 15, 2016  Synthetic Biologics, Inc. (NYSE MKT: ... on the gut microbiome, today announced the pricing ... of its common stock and warrants to purchase ... price to the public of $1.00 per share ... from the offering, excluding the proceeds, if any ...
(Date:6/22/2016)... BETHESDA, Md. , June 22, 2016  The American ... by Trade Show Executive Magazine as one of ... Summit on May 25-27 at the Bellagio in ... based on the highest percentage of growth in each of ... number of exhibiting companies and number of attendees. The 2015 ...
(Date:6/16/2016)... SAN FRANCISCO , June 16, 2016 /PRNewswire/ ... Market size is expected to reach USD ... report by Grand View Research, Inc. Technological proliferation ... and banking applications are expected to drive the ... ) , The development of ...
Breaking Biology News(10 mins):
(Date:12/6/2016)... ... December 06, 2016 , ... ... Group, the world’s largest privately-held contract pharmaceutical development and manufacturing organisation, ... leading biopharma outsourcing company combining a leading CRO and the industry’s only ...
(Date:12/6/2016)... NJ (PRWEB) , ... December 06, 2016 , ... ... paper on December 1, 2016 asking the Federal Drug Administration (FDA) to consider ... study of OA, OARSI is concerned about the growing population of OA patients, ...
(Date:12/6/2016)... ... 06, 2016 , ... Discovering new clues to natural treatments that could allow ... in our brains. And searching for keys to our immune systems by studying parasite-resistant ... the 2017 Edith and Peter O’Donnell Awards by The Academy of ...
(Date:12/6/2016)... Albany, NY (PRWEB) , ... December 06, 2016 ... ... system integrator of custom industrial automation and IT solutions, today announced the company ... Controls has reliably delivered professionally executed automation and control systems integration services to ...
Breaking Biology Technology:
Cached News: