HOME >> BIOLOGY >> NEWS
EPA-led group finds same protein that attracts nutrient iron protects lung from particles

So what's DMT1 doing in the liver, kidneys and brain?

BETHESDA, Md. (Oct. 3, 2005) Multi-vitamin products, nutritional supplements and parents tout the need for such mineral elements as calcium, zinc, phosphorus, iron and others.

Iron, for example, is a nutritional prerequisite to power life itself. When blood doesn't get enough iron from the gut, we become anemic. One of the body's coping mechanisms is to produce more of a protein called divalent metal transporter 1 (DMT1) in the gastrointestinal lining cells to bring into the body as much iron as possible. Until recently DMT1 was exclusively studied for its nutritional role in transporting iron.

But put iron or other air-borne particulates into our lungs and they can cause health problems ranging from asthma and acute respiratory distress syndrome to asbestosis and lung cancer.

In a recently-published paper a group of EPA-led lung researchers reported experiments demonstrating for the first time that "DMT1 is essential for the transport and detoxification of some metals associated with an air pollution particle that damages the pulmonary epithelial surface."

The paper "Divalent metal transporter-1 decreases metal-related injury in the lung" appears in the American Journal of Physiology-Lung Cellular and Molecular Physiology, published by the American Physiological Society. Research was performed by Andrew J. Ghio, Lisa A. Dailey, Jacqueline D. Stonehuerner and Michael C. Madden from the U.S. Environmental Protection Agency; Claude A. Piantadosi of Duke University; Xinchao Wang of University of North Carolina; Funmei Yang of University of Texas; and Kevin G. Dolan, Michael D. Garrick and Laura M. Garrick of SUNY-Buffalo.

Lead researcher Andrew Ghio said this breakthrough discovery of DMT1 lung protection could prompt studies of its roles in other organs where it's found. "For instance, DMT1 is in the liver, kidneys and brain, where it's not needed f
'"/>


3-Oct-2005


Page: 1 2 3 4

Related biology news :

1. Neurons for numerosity: Parietal neurons sum up individual items in a group
2. Johns Hopkins Bloomberg School of Public Health, Geisinger launch new environmental research group
3. Research group gets $7 million to pursue new antibiotic agents
4. Gene study shows three distinct groups of chimpanzees
5. No sign that ethnic groups genes cause diabetes, international research team says
6. Fisheries group calls for science-based approach to address climate impacts
7. 20 of worlds 162 grouper species threatened with extinction
8. Genes and groups of genes commonly shared between species, studies show
9. New group of algae discovered: Picobiliphytes
10. The case of the snuggling skunks -- Is it better to brave winter alone or in a group?
11. 1st international study group for new movement discipline

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/6/2017)... -- Forecasts by Product Type (EAC), Biometrics, ... (Transportation & Logistics, Government & Public Sector, Utilities / ... Facility, Nuclear Power), Industrial, Retail, Business Organisation (BFSI), Hospitality ... looking for a definitive report on the $27.9bn Access ... ...
(Date:4/4/2017)...   EyeLock LLC , a leader of iris-based ... Patent and Trademark Office (USPTO) has issued U.S. Patent ... an iris image with a face image acquired in ... 45 th issued patent. "The ... the multi-modal biometric capabilities that have recently come to ...
(Date:3/30/2017)... , March 30, 2017 Trends, opportunities ... (physiological and behavioral), by technology (fingerprint, AFIS, iris recognition, ... recognition, and others), by end use industry (government and ... immigration, financial and banking, and others), and by region ... , Asia Pacific , and ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... October 11, 2017 , ... ComplianceOnline’s Medical Device Summit is back for ... June 2018 in San Francisco, CA. The Summit brings together current and former FDA ... board directors and government officials from around the world to address key issues in ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... implantation and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... and maternal age to IVF success. , After comparing the results from the ...
(Date:10/10/2017)... ... October 10, 2017 , ... Dr. Bob Harman, founder and CEO of ... Rotary Club. The event entitled “Stem Cells and Their Regenerative Powers,” ... Dr. Harman, DVM, MPVM was joined by two human doctors: Peter B. Hanson, ...
(Date:10/9/2017)... SAN DIEGO , Oct. 9, 2017 /PRNewswire/ ... a biological mechanism by which its ProCell stem ... of critical limb ischemia.  The Company, demonstrated that ... the amount of limbs saved as compared to ... of the molecule HGF resulted in reduction of ...
Breaking Biology Technology:
Cached News: