HOME >> BIOLOGY >> NEWS
Early exposure to synthetic estrogen puts 'DES Daughters' at higher risk for breast cancer

Philadelphia -- So-called "DES daughters," born to mothers who used the anti-miscarriage drug diethylstilbestrol during pregnancy, are at a substantially greater risk of developing breast cancer compared to women who were not exposed to the drug in utero.

Reporting in the August issue of the journal Cancer Epidemiology, Biomarkers & Prevention, a nationwide team of researchers found that DES daughters over age 40 had 1.9 times the risk of developing breast cancer, compared to unexposed women of the same age. They also found that the relative risk of developing the cancer was even greater in DES daughters over age 50, but say the number of older women in their study group is, as yet, too small for a firm statistical comparison.

"This is really unwelcome news because so many women worldwide were prenatally exposed to DES, and these women are just now approaching the age at which breast cancer becomes more common," said the study's lead author, Julie Palmer, Sc.D., professor of epidemiology at the Boston University School of Public Health.

She said an estimated one to two million women in the U.S. were exposed to DES, which was frequently prescribed to women from the 1940s through 1960s to prevent miscarriages.

The ongoing study suggests that DES-exposed women are developing the typical range of breast cancers after age 40 at a faster rate than non-exposed women of the same ages. The researchers also found that the highest relative risk of developing breast cancer was observed in study participants from the cohorts with the highest cumulative doses of DES exposure.

Because of the increased risk observed for DES daughters, the authors urge women who know they were exposed to DES to have regular screening mammograms, and to think twice about using supplemental female hormones.

"DES daughters often ask us about use of these hormones," Palmer said. "It might be wise for exposed women to avoid s
'"/>

Contact: Warren Froelich
froelich@aacr.org
215-440-9300
American Association for Cancer Research
7-Aug-2006


Page: 1 2 3

Related biology news :

1. Early fire risk for mountains near Los Angeles
2. Early environmental exposure may accelerate age-related neurodegeneration
3. Early exposure to indoor fungus molecules may protect infants against future allergies
4. Early-stage sperm cells created from human bone marrow
5. Early Europeans unable to stomach milk
6. Early HIV treatment fails to restore memory T cells
7. Early Earth haze may have spurred life, says University of Colorado study
8. Early detection
9. Early family experience can reverse the effects of genes, UCLA psychologists report
10. Early to bed, early to rise
11. Top researcher-educators receive Presidential Early Career Award for Scientists and Engineers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/7/2020)... Ky. (PRWEB) , ... August 06, 2020 , ... ... selected to participate in the prestigious National STEM Scholar Program, a unique professional ... network building, and project support for middle school science teachers nationwide. , Created ...
(Date:7/22/2020)... (PRWEB) , ... July 21, 2020 , ... ... digital transformation and innovation in technology and compliance, announces a new solution to ... companies must ensure every layer of their technology stack complies with FDA and ...
(Date:7/4/2020)... ... July 03, 2020 , ... ... earn outstanding recognition and multiple awards for not only the products and treatments ... SoME® Skincare and Vivace® Microneedle RF. All the brands built by ABM have ...
Breaking Biology News(10 mins):
(Date:7/10/2020)... (PRWEB) , ... July 09, 2020 , ... ... to cell therapy, today announced the hiring of Allen R. Nissenson, M.D., F.A.C.P., ... and oversee the clinical development of Sentien’s lead product, SBI-101. Dr. Nissenson ...
(Date:7/7/2020)... ... 2020 , ... Bio-IT World has announced the winners of ... University of Chicago, Massachusetts General Hospital, Mission: Cure, and the Pistoia Alliance were ... outstanding examples of how technology innovations and strategic initiatives can be powerful forces ...
(Date:7/1/2020)... ... June 29, 2020 , ... ... procured purchasing contracts to its membership, recently named BioFit Engineered Products ... the opportunity to purchase ergonomic seating, cafeteria tables, book trucks and carts at ...
(Date:6/28/2020)... , ... June 25, 2020 , ... The Indoor Lab, ... of Safe Space™ for businesses of all types to ensure cleanliness, distancing and occupancy ... , A Safe Space™ enabled business will provide a health performance index system ...
Breaking Biology Technology:
Cached News: