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Early life stress harms mental function and immune system in later years

matin Structure and Gene Expression," Tuesday, October 26, at 11:15 a.m.

In the rat, maternal effects on stress responses involve stable, postnatal alterations in chromatin structure such as DNA methylation. "Early experience can actually modify protein-DNA interactions that regulate gene expression," Meaney says. "The effects of mother-infant interaction on chromatin structure might define a basis for the development of stable individual differences in hormone function and behavior over the lifespan."


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Contact: Leah Ariniello
dawn@sfn.org
202-462-6688
Society for Neuroscience
24-Oct-2004


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