HOME >> BIOLOGY >> NEWS
Endogenous cannabinoids linked to fetal brain damage imposed by maternal cannabis use

A critical step in brain development is governed by endogenous cannabinoids, the brains own marijuana. Studies conducted at Swedish medical university Karolinska Institutet, with participation of scientists from Europe and the United States, are now published in Science and show that these endogenous molecules regulate how certain nerve cells recognize each other and form connections. The scientists believe that their findings will significantly advance our understanding of how cannabis smoking during pregnancy may damage the fetal brain.

The formation of connections among nerve cells occurs during a relatively short period in the fetal brain. However, proper wiring of hundreds of millions of cells in our brains determine whether we can think, remember, move, or show emotions throughout our lives. For a nerve cell, recognizing its partners and establish connections with them is the key to survive and contribute to the control of brain functions. The process through which nerve cells recognize each other is guided by specific chemical signals whose availability instructs neurons to target or to ignore specific cells.

Scientists have now identified that endogenous cannabinoids, molecules naturally produced by our brains and functionally similar to THC from cannabis, play unexpectedly significant roles in establishing how certain nerve cells connect to each other. These new and exciting results not only bolster out knowledge on the brains normal development but may also take us closer to understanding if and when cannabis damages the fetal brain.

Endogenous cannabinoids use the same mechanism, engaging the CB1 cannabinoid receptor, as THC to exert their effects on nerve cells. Therefore, the finding that endogenous cannabinoids control the establishment of connections amongst certain nerve cells convinces the scientists that they have defined a key mechanism through which maternal cannabis use might impair fetal brain development and impos
'"/>

Contact: Tibor Harkany
Tibor.Harkany@ki.se
46-852-487-835
Karolinska Institutet
24-May-2007


Page: 1 2

Related biology news :

1. Endocannabinoids the brains cannabis demonstrate novel modes of action to stress
2. Protein chatter linked to cancer activation
3. Risk of common vaginal infection linked to preterm birth appears higher for blacks
4. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
5. Antibody linked to MS significantly higher in spinal fluid of blacks
6. Loss of cells antenna linked to cancers development
7. Scientists identify first gene linked to scoliosis
8. Gum disease in postmenopausal women linked to oral bone loss
9. Screening approach leads to discovery of gene linked to breast cancer
10. Sensitivity to diverse range of chemotherapeutic drugs linked to common pathway
11. Dietary preferences and patterns may be linked to genes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/1/2019)... Fla. (PRWEB) , ... July 31, 2019 , ... ... technologies for personalized treatment. Check your local listings for more information. , Factor ... and treatment of cancer and genetic and age-related diseases. This segment of Advancements ...
(Date:7/24/2019)... ... July 24, 2019 , ... NDA Partners Chairman ... assurance expert with more than 20 years of experience working in scientific research ... the firm as an Expert Consultant. , Dr. Hartzfeld has experience in all ...
(Date:7/21/2019)... ... July 20, 2019 , ... ... ) announced today the release of the biggest software update in its ... platform will provide a significant increase in productivity for its users. ...
Breaking Biology News(10 mins):
(Date:8/14/2019)... ... August 13, 2019 , ... Chata was ... for QC laboratories. After gaining a few significant clients, Lifecycle purchased the company ... valued supplier of manufacturing processing solutions, including reagents for tissue processing. Chata quickly ...
(Date:8/6/2019)... ... August 06, 2019 , ... The San Diego Biotechnology Network ... biweekly SDBN BUZZ podcast focused on connecting the region’s biotech community and discussing ... promote the region and attract external employers, investors, scientists, and others who wish ...
(Date:8/6/2019)... Ill. (PRWEB) , ... August 06, 2019 , ... ... Southern Illinois University Edwardsville for the launch of a community project that will ... The three-year grant supports the project, entitled “A Youth-Led Citizen Science Network for ...
(Date:7/26/2019)... , ... July 25, 2019 , ... ... leaders through off-the-record collaboration and dialogue, today announces its Boston BD ... Hotel. As part of Biotech Week Boston , the event provides an ...
Breaking Biology Technology:
Cached News: