HOME >> BIOLOGY >> NEWS
Essential genes cluster clue to order in the genome

HOUSTON (May 3, 2007) The identification of a cluster of essential genes on mouse chromosome 11 as well as similar clusters on the chromosomes of other organisms including humans buttresses the argument that there may be rules as to how genes are structured or laid out on chromosomes, said the Baylor College of Medicine senior author of a report that appears online today in the Public Library of Science Genetics, an open-access publication.

"There may be a real code to chromosomal organization," said Dr. Monica Justice, associate professor of molecular and human genetics at BCM and an expert in mouse genomics. Chromosomes are cellular structures that contain genes. Humans have 23 pairs. One of each pair comes from the mother; the other from the father.

This is the first time anyone has been able to look at the issue of essential genes in the mouse, said Justice. Essential genes are those that are crucial to the life of an organism. When these genes are lacking, the animal does not develop normally and dies.

"The area of mouse chromosome 11 on which we focused is homologous to or has the same genes as human chromosome 17," said Justice. "It is very gene-rich, but it also seems to have a lot of genes that when mutated, cause the animal to die."

She said she and her colleagues chose this chromosome because all the genes present on the homologous region on human 17 could actually be found on mouse chromosome 11.

"When we saw that there were all these essential genes in this region, we wondered if the reason that the chromosome remained together (and is not easily broken apart or recombined with other parts of this or other chromosomes) is that it had all these densely packed essential genes," said Justice.

With the aid of a computer program developed by Dr. Bin Liu at Baylor College of Medicine, the researchers analyzed this region across species as diverse as possum, cow, dog and chimp.

"We
'"/>

Contact: Kimberlee Barbour
kbarbour@bcm.edu
713-798-4710
Baylor College of Medicine
3-May-2007


Page: 1 2

Related biology news :

1. Essential tones of music rooted in human speech
2. Essential genes for embryogenesis uncovered in major mouse mutagenesis project
3. Essential mangrove forest threatened by cryptic ecological degradation
4. Essential oils could help to stamp out MRSA
5. Interaction of just 2 genes governs coloration patterns in mice
6. Gene regulation, not just genes, is what sets humans apart
7. Study finds gender differences in renal and other genes contributing to blood pressure
8. New databases put wings on search for bipolar risk genes
9. Research teams uncover risk genes for multiple sclerosis
10. Risk genes for multiple sclerosis uncovered
11. Sour taste make you pucker? It may be in your genes

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Essential genes cluster clue order the genome

(Date:12/3/2014)... 2, 2014 As part of our commitment ... is pleased to announce the release of a new ... collect the workforce data that they need. ... left by existing readers. Many such devices have serious ... modern technology. Older models force users to navigate numerous ...
(Date:11/21/2014)... YORK , Nov. 19, 2014  Earlier this ... at New York College, and one of the most ... biosensor signals that are transmitted from Smartphones to third ... were Smartphones and has one of the earliest known ... discussing its usage in the military, child care, elder ...
(Date:11/21/2014)... 2014 C-Labs LLC, a leading provider of ... (IoT), today announced the appointment of John Traynor ... a strategic advisor to the firm, Mr. Traynor will ... is based out of the C-Labs office in ... Chris Muench , Chief Executive Officer. Photo ...
Breaking Biology News(10 mins):Inception Technologies to Release New Biometric Reader 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2
(Date:12/22/2014)... The American Journal of Hematology/Oncology, ... and editorials addressing developments and pathways related to ... provocative article exploring the role of follicle-stimulating hormone ... of prostate cancer. , The article references ... that there could be a connection to prostate ...
(Date:12/19/2014)... 2014 BioPlus Specialty Pharmacy ... the promotion of Nick Maroulis, Pharm.D. to the newly ... , In this position, Dr. Maroulis will continue ... the directors of our multi-site pharmacies as the company ... and during that time he has served in many ...
(Date:12/19/2014)... 2014 Research and Markets ( ... "Technology Innovations in Smart Fabrics (Technical Insights)" ... http://photos.prnewswire.com/prnh/20130307/600769 The Research ... a detailed assessment on technological advancements and market ... 1. The Smart Fabrics market is ...
(Date:12/19/2014)... Reports from CDC show approximately ... one or more chronic health conditions - including cardiovascular ... some of these diseases, but may not eliminate the ... While implanted nerve stimulation devices today offer relief, they ... can induce side effects. , To eliminate the ...
Breaking Biology Technology:Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 2Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 3Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 4BioPlus Specialty Pharmacy Promotes Dr. Nick Maroulis to Vice President of Specialty Pharmacy Services 2Technology Innovations in Smart Fabrics (Technical Insights) 2Draper Wins GSK Funding for Smaller, Smarter Implantable Devices 2
Cached News: