HOME >> BIOLOGY >> NEWS
Essential genes cluster clue to order in the genome

HOUSTON (May 3, 2007) The identification of a cluster of essential genes on mouse chromosome 11 as well as similar clusters on the chromosomes of other organisms including humans buttresses the argument that there may be rules as to how genes are structured or laid out on chromosomes, said the Baylor College of Medicine senior author of a report that appears online today in the Public Library of Science Genetics, an open-access publication.

"There may be a real code to chromosomal organization," said Dr. Monica Justice, associate professor of molecular and human genetics at BCM and an expert in mouse genomics. Chromosomes are cellular structures that contain genes. Humans have 23 pairs. One of each pair comes from the mother; the other from the father.

This is the first time anyone has been able to look at the issue of essential genes in the mouse, said Justice. Essential genes are those that are crucial to the life of an organism. When these genes are lacking, the animal does not develop normally and dies.

"The area of mouse chromosome 11 on which we focused is homologous to or has the same genes as human chromosome 17," said Justice. "It is very gene-rich, but it also seems to have a lot of genes that when mutated, cause the animal to die."

She said she and her colleagues chose this chromosome because all the genes present on the homologous region on human 17 could actually be found on mouse chromosome 11.

"When we saw that there were all these essential genes in this region, we wondered if the reason that the chromosome remained together (and is not easily broken apart or recombined with other parts of this or other chromosomes) is that it had all these densely packed essential genes," said Justice.

With the aid of a computer program developed by Dr. Bin Liu at Baylor College of Medicine, the researchers analyzed this region across species as diverse as possum, cow, dog and chimp.

"We
'"/>

Contact: Kimberlee Barbour
kbarbour@bcm.edu
713-798-4710
Baylor College of Medicine
3-May-2007


Page: 1 2

Related biology news :

1. Essential tones of music rooted in human speech
2. Essential genes for embryogenesis uncovered in major mouse mutagenesis project
3. Essential mangrove forest threatened by cryptic ecological degradation
4. Essential oils could help to stamp out MRSA
5. Interaction of just 2 genes governs coloration patterns in mice
6. Gene regulation, not just genes, is what sets humans apart
7. Study finds gender differences in renal and other genes contributing to blood pressure
8. New databases put wings on search for bipolar risk genes
9. Research teams uncover risk genes for multiple sclerosis
10. Risk genes for multiple sclerosis uncovered
11. Sour taste make you pucker? It may be in your genes

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Essential genes cluster clue order the genome

(Date:7/31/2015)... Den 10. internationale konference om Genomik (ICG-10, ... - 25. oktober i Shenzhen , ... i år. Siden starten i 2006 er ICB blevet ... og er en af de mest dynamiske, entusiastiske og ... nylige gennembrud og fremskridt inden for ,omik,-forskning, som yderligere ...
(Date:7/31/2015)... de julio de 2015 BGI llevará a cabo ... del 22 al 25 de octubre de 2015, en ... conferencia celebra su décimo aniversario este año. Desde su ... de las reuniones anuales más influyentes del mundo en ... las conferencias científicas más dinámicas, entusiastas y amenas. ...
(Date:7/31/2015)... SHENZHEN, China , 31 de julho de 2015 ... Genômica (ICG-10, www.icg-10.org ) será realizada pela BGI de ... China . A conferência está ... inauguração em 2006, a ICG se tornou uma das ... e um dos encontros científicos mais dinâmicos, entusiastas e ...
Breaking Biology News(10 mins):Den 10. internationale konference om Genomics (ICG-10) åbner i oktober 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 3A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 2A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 3
(Date:7/30/2015)... , July 30, 2015  With over 60,000 customers across the globe, ISN ... connect 450 hiring organizations with more than 60,000 safe and reliable contractors in over 80 countries. ... ... ... Headquartered in Dallas, TX ...
(Date:7/30/2015)... ST. LOUIS, July 30, 2015 ... period in 2014) , Reported sales were $697 ... of 2014.  Sales grew organically by 8%, and changes ... Recent acquisitions increased sales by 1%. , By ... 8% in Applied and 11% in SAFC Commercial. ...
(Date:7/30/2015)... NY (PRWEB) , ... July 30, 2015 , ... As part of its 2015 growth ... material and technical service business units, Whitehouse Laboratories is pleased to announce ... be adjacent to the Container Center of Excellence and will be strictly dedicated to basic ...
(Date:7/29/2015)... July 30, 2015 Sanofi, ... for the second quarter of 2015. CEO ... and its performance in different businesses. ... http://www.eurobusinessmedia.com/ceo-direct/sanofi/sanofi-h1-2015-results-interview-with-ceo-olivier-brandicourt?utm_source=ceo-direct&utm_medium=wire Topics covered in ... - Performance drivers - ...
Breaking Biology Technology:ISN Reaches Over 60,000 Worldwide Customers 2ISN Reaches Over 60,000 Worldwide Customers 3Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 2Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 3Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 4Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 5Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 6Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 7Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 8Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 9Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 10Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 11Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 12Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 13Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 14Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 15Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 16Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 17Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 18Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 19Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 20Whitehouse Labs Formally Announces Plans to Open a Microbiological Laboratory 2
Cached News: