HOME >> BIOLOGY >> NEWS
Essential genes cluster clue to order in the genome

HOUSTON (May 3, 2007) The identification of a cluster of essential genes on mouse chromosome 11 as well as similar clusters on the chromosomes of other organisms including humans buttresses the argument that there may be rules as to how genes are structured or laid out on chromosomes, said the Baylor College of Medicine senior author of a report that appears online today in the Public Library of Science Genetics, an open-access publication.

"There may be a real code to chromosomal organization," said Dr. Monica Justice, associate professor of molecular and human genetics at BCM and an expert in mouse genomics. Chromosomes are cellular structures that contain genes. Humans have 23 pairs. One of each pair comes from the mother; the other from the father.

This is the first time anyone has been able to look at the issue of essential genes in the mouse, said Justice. Essential genes are those that are crucial to the life of an organism. When these genes are lacking, the animal does not develop normally and dies.

"The area of mouse chromosome 11 on which we focused is homologous to or has the same genes as human chromosome 17," said Justice. "It is very gene-rich, but it also seems to have a lot of genes that when mutated, cause the animal to die."

She said she and her colleagues chose this chromosome because all the genes present on the homologous region on human 17 could actually be found on mouse chromosome 11.

"When we saw that there were all these essential genes in this region, we wondered if the reason that the chromosome remained together (and is not easily broken apart or recombined with other parts of this or other chromosomes) is that it had all these densely packed essential genes," said Justice.

With the aid of a computer program developed by Dr. Bin Liu at Baylor College of Medicine, the researchers analyzed this region across species as diverse as possum, cow, dog and chimp.

"We
'"/>

Contact: Kimberlee Barbour
kbarbour@bcm.edu
713-798-4710
Baylor College of Medicine
3-May-2007


Page: 1 2

Related biology news :

1. Essential tones of music rooted in human speech
2. Essential genes for embryogenesis uncovered in major mouse mutagenesis project
3. Essential mangrove forest threatened by cryptic ecological degradation
4. Essential oils could help to stamp out MRSA
5. Interaction of just 2 genes governs coloration patterns in mice
6. Gene regulation, not just genes, is what sets humans apart
7. Study finds gender differences in renal and other genes contributing to blood pressure
8. New databases put wings on search for bipolar risk genes
9. Research teams uncover risk genes for multiple sclerosis
10. Risk genes for multiple sclerosis uncovered
11. Sour taste make you pucker? It may be in your genes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/12/2020)... ... August 11, 2020 , ... Both Roche, based ... entered into license agreements with Housey Pharma’s HMI subsidiary to gain access to ... have annual Research and Development spending in excess of US $10 billion. , ...
(Date:8/3/2020)... (PRWEB) , ... August 03, 2020 , ... ... company announced a new partnership with medical equipment manufacturer, Spectrum Solutions, to provide ... clients to strengthen their laboratory supply chain for more than 10 years. Early ...
(Date:7/18/2020)... (PRWEB) , ... July 17, 2020 , ... Commercial launch ... on pharma’s ability to discover a COVID cure or vaccine, the global economic downturn ... and price pressure is not going away and capturing full value from every product ...
Breaking Biology News(10 mins):
(Date:8/12/2020)... ... August 12, 2020 , ... Inc. magazine today ... leader in FDA compliance consulting has been named on its annual Inc. 5000 ... represents a unique look at the most successful companies within the American economy’s ...
(Date:7/31/2020)... (PRWEB) , ... July 29, 2020 , ... ... today announced the launch of its new tagline, “BUILDING FOR LIFE.” The adoption ... industry and around the globe, requiring fast track capacity to provide patients with ...
(Date:7/31/2020)... ... July 29, 2020 , ... The SDX® ... in 16 countries, has reached its 20th anniversary of worldwide use. Introduced in ... at top universities including University of Pennsylvania, University of Michigan, University of Maryland, ...
(Date:7/18/2020)... ... 16, 2020 , ... Medial EarlySign , a leader ... of high-burden diseases, and Centric Consulting, a business and technology consulting firm, today ... data in order to identify and prioritize patients for care. , Combining Centric’s ...
Breaking Biology Technology:
Cached News: