HOME >> BIOLOGY >> NEWS
Essential genes cluster clue to order in the genome

HOUSTON (May 3, 2007) The identification of a cluster of essential genes on mouse chromosome 11 as well as similar clusters on the chromosomes of other organisms including humans buttresses the argument that there may be rules as to how genes are structured or laid out on chromosomes, said the Baylor College of Medicine senior author of a report that appears online today in the Public Library of Science Genetics, an open-access publication.

"There may be a real code to chromosomal organization," said Dr. Monica Justice, associate professor of molecular and human genetics at BCM and an expert in mouse genomics. Chromosomes are cellular structures that contain genes. Humans have 23 pairs. One of each pair comes from the mother; the other from the father.

This is the first time anyone has been able to look at the issue of essential genes in the mouse, said Justice. Essential genes are those that are crucial to the life of an organism. When these genes are lacking, the animal does not develop normally and dies.

"The area of mouse chromosome 11 on which we focused is homologous to or has the same genes as human chromosome 17," said Justice. "It is very gene-rich, but it also seems to have a lot of genes that when mutated, cause the animal to die."

She said she and her colleagues chose this chromosome because all the genes present on the homologous region on human 17 could actually be found on mouse chromosome 11.

"When we saw that there were all these essential genes in this region, we wondered if the reason that the chromosome remained together (and is not easily broken apart or recombined with other parts of this or other chromosomes) is that it had all these densely packed essential genes," said Justice.

With the aid of a computer program developed by Dr. Bin Liu at Baylor College of Medicine, the researchers analyzed this region across species as diverse as possum, cow, dog and chimp.

"We
'"/>

Contact: Kimberlee Barbour
kbarbour@bcm.edu
713-798-4710
Baylor College of Medicine
3-May-2007


Page: 1 2

Related biology news :

1. Essential tones of music rooted in human speech
2. Essential genes for embryogenesis uncovered in major mouse mutagenesis project
3. Essential mangrove forest threatened by cryptic ecological degradation
4. Essential oils could help to stamp out MRSA
5. Interaction of just 2 genes governs coloration patterns in mice
6. Gene regulation, not just genes, is what sets humans apart
7. Study finds gender differences in renal and other genes contributing to blood pressure
8. New databases put wings on search for bipolar risk genes
9. Research teams uncover risk genes for multiple sclerosis
10. Risk genes for multiple sclerosis uncovered
11. Sour taste make you pucker? It may be in your genes

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Essential genes cluster clue order the genome

(Date:4/15/2014)... and energy for nearly all life on Earth, yet ... example, little is known about how it is regulated ... we do not know the full list of the ... any organism. , , A type of single-cell green ... subject for photosynthesis research. Despite its importance in the ...
(Date:4/15/2014)... In a study of nearly 1,000 mother-child pairs, ... found that prenatal exposure to selective serotonin reuptake ... anxiety and other disorders, was associated with autism ... boys. The study, published in the online edition ... samples of ASD and DD cases, and population-based ...
(Date:4/15/2014)... If an insect drew a line as it ... a tangled mess. But there,s method to that mess, ... engineering and physics, who tries to find simple physical ... https://cornell.box.com/tbeetle , It turns out the tiger beetle, ... reorientation dance as it chases its prey at blinding ...
Breaking Biology News(10 mins):Study: SSRI use during pregnancy associated with autism and developmental delays in boys 2Photo: Tiger beetle's chase highlights mechanical law 2
(Date:1/15/2014)... January 15, 2014 This webinar ... on nonclinical and clinical safety assessment in biosimilars. ... guide a path for biosimilar drug development, however ... of biosimilarity with regards to quality, safety and ... of biosimilar drug development and registration, development strategies ...
(Date:1/15/2014)... NC (PRWEB) January 15, 2014 ... an enhancement to its Online Web Portal for Life ... now have the ability to specify the subject matter ... nearly 50 life science sub-domains. This will help reduce ... and scientific fields, and decrease the likelihood of error. ...
(Date:1/14/2014)... Doylestown, PA (PRWEB) January 14, 2014 ... – 11 p.m. , Location: Warrington Country Club, 1360 ... Hepatitis B Foundation, the only national nonprofit organization solely ... improving the quality of life for those affected worldwide, ... 11 at Warrington Country Club in Warrington, Pa. ...
(Date:1/14/2014)... York, NY (PRWEB) January 14, 2014 ... initiated coverage of Alliqua, Inc. (OTCQB: ALQA). Alliqua ... and marketing proprietary products to serve the wound ... , In late 2012, Alliqua was restructured ... launched the company’s new strategy to become a ...
Breaking Biology Technology:Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2DTS Improves Efficiency for Life Science Document Translations 2Hepatitis B Foundation to Host Annual Crystal Ball Gala 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
Cached News: