Experimental evolution of yeast in the lab may illuminate early events in speciation

By experimentally promoting rapid, small-scale evolution within a lab population of yeast, researchers have shed light on the kinds of genetic changes that may underlie the emergence of new species.

A fundamental tenet of Darwin's theory of evolution was that new species arise from older ones. Biologists typically define species on the basis of the ability of individuals to mate and produce fertile offspring; if two organisms can accomplish this feat, they belong to the same species, and if they cannot, they belong to separate species. Theoretically, a species can split into two when genetic barriers arise that keep two geographically mixed groups (populations) of the species from mating with each other. But what sorts of genetic barriers might arise in a living population that could lead to this kind of reproductive barrier?

Scientists Jun-Yi Leu and Andrew Murray at Harvard University have recapitulated what may be early stages of speciation by evolving populations of brewer's yeast in the laboratory. The researchers took a single strain of yeast and genetically engineered it to create an evolving population, which was subject to special selective forces, and a reference population, which was not.

At the beginning of the experiment, a yeast cell in the evolving population was equally likely to mate with a cell in either the reference population or the evolving population. To change the cells' preferred partners, the researchers mixed the two populations, allowed them to mate, and then used engineered genes to create a selective force such that offspring from a mating of two cells from the evolving population were selectively allowed to survive while offspring from a cross between the evolving population and the reference population, or a cross between two yeasts from the reference population, died. By repeating this selection process for 36 generations, the researchers produced evolved populations that were five times more likely to mate

Contact: Heidi Hardman
Cell Press

Page: 1 2

Related biology news :

1. 38 minority scientists receive travel fellowships to Experimental Biology 2007 in D.C.
2. Experimental Biology 2007: Todays Research, Tomorrows Health, April 28-May 2
3. Experimental Biology 2007 meets in Washington, D.C., April 28-May 2
4. Experimental cancer drugs counter muscle deterioration seen in muscular dystrophy
5. Experimental RNA-based drug kills prostate cancer cells effectively and safely
6. Experimental vaccine protects nonhuman primates when given after exposure to Marburg virus
7. Undergrads compete for American Physiological Society Bruce awards at Experimental Biology
8. Experimental drug reverses key cognitive deficits, pathology in Alzheimers
9. Experimental TB drug effective against resistant and latent mycobacterium tuberculosis
10. Advancing the biomedical frontier: Experimental Biology 2006
11. Experimental Biology 2006 meets in San Francisco April 1-5

Post Your Comments:

(Date:7/2/2020)... CITY, Calif. (PRWEB) , ... July 01, 2020 ... ... biotech company, presented its phase 1a findings of Neihulizumab, a biologic for the ... conference in June 2020. Led by hemato-oncologist Dr. Paul J Martin of the ...
(Date:7/1/2020)... Calif. (PRWEB) , ... July 01, 2020 , ... ... on building awareness and solutions for glioblastoma—the most common and aggressive adult brain ... Lisa Haile, JD, PhD. Senior Fellows are charged with supporting the organization’s initiatives ...
(Date:6/25/2020)... ... June 24, 2020 , ... ... software-driven clinical data services that accelerate drug development, is collaborating with Karyopharm Therapeutics ... inhibitor, in hospitalized patients with severe COVID-19. This is the first study of ...
Breaking Biology News(10 mins):
(Date:7/18/2020)... DAYTON, Ohio (PRWEB) , ... July 16, 2020 ... ... clinical data solutions to aid in the early detection and prevention of high-burden ... partnership to enable US-based hospitals and healthcare organizations to utilize existing data in ...
(Date:7/10/2020)... ... July 09, 2020 , ... PathSensors Inc., ... has expanded the company’s exclusive license to include clinical applications for CANARY™ ... market, focusing initially on the SARS-CoV-2 biosensor. CANARY’s™ fast and highly ...
(Date:7/7/2020)... ... July 06, 2020 , ... R3 International is now ... up to 200 million stem cells. Depending on the patient's condition, treatment may be ... US will die having some form of Alzheimers dementia, and the incidence continues to ...
(Date:7/1/2020)... BOWLING GREEN, Ohio (PRWEB) , ... June 29, ... ... cooperative that offers access to competitively procured purchasing contracts to its membership, recently ... BioFit to provide TIPS members with the opportunity to purchase ergonomic seating, cafeteria ...
Breaking Biology Technology:
Cached News: