HOME >> BIOLOGY >> NEWS
Fake malaria drug implicated in Burmese man's death

A 23-year old man in Burma with malaria died because the medicine he received was fake, according to an investigative report by an international team of researchers published in PLoS Medicine.

The patient went to a rural hospital in East Burma with a fever and was diagnosed as having a straightforward case of falciparum malaria. He was treated with the vital antimalarial drug artesunate, labeled as made by the company Guilin Pharmaceutical in China. This drug is usually extremely effective, yet the patient went into a coma and died.

The researchers, led by Paul Newton (University of Oxford), analyzed the artesunate tablets that had been used to treat the patient and found that they were fake, containing just 20% of the amount of active drug present in a genuine artesunate tablet.

When genuine artesunate was given to 600 patients with straightforward falciparum malaria in a study in East Burma, every single patient survived. Newton and colleagues conclude that the 23-year old man died from being given fake artesunate.

"Counterfeit artesunate continues to circulate on a vast scale in mainland Southeast Asia," say the authors. So far, only the Guilin Pharmaceutical brand of artesunate has been counterfeited.

Genuine artesunate is relatively expensive, creating a demand among poor, vulnerable people for cheaper alternatives--the counterfeiters, say the authors, are thus preying upon the poor.

Newton and colleagues fear that an epidemic of fake artesunate may also follow in the wake of the genuine artesunate that is being imported for use in sub-Saharan Africa, where the burden of malaria is greatest. The high cost and the shortage of genuine artesunate in Africa provide a favorable situation for the spread of fakes, which could put the lives of thousands of children at risk.

Fake artesunate was found in Cameroon in 2005, and fake dihydroartemisinin (a related antimalarial drug) was reported in Tanzani
'"/>

Contact: Andrew Hyde
ahyde@plos.org
44-122-346-3330
Public Library of Science
12-Jun-2006


Page: 1 2

Related biology news :

1. Edible fish feasts beats malaria
2. Identified mechanism in the malaria parasite to help it adapt to infected individuals
3. CRESIB coordinates an international consortium to fight malaria caused by Plasmodium vivax
4. Key to tackling malaria may lie in bed nets for adults and older children
5. Largest synthetic gene ever built offers insights into anti-malarial drug resistance
6. MIT-led team uncovers malaria mechanism
7. Vaccine hope for malaria
8. Antibody-based therapies effective at controlling malaria
9. Researchers identify key protein in immune response to malaria and TB
10. G6PD deficiency is associated with significant protection against severe, life-threatening malaria
11. Potential for malaria transmission higher than previously thought

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/14/2019)... ... November 13, 2019 , ... ... Robert Peterson, RAC , a regulatory affairs and program management executive with more ... medical device industries, has joined the firm as an Expert Consultant. , ...
(Date:11/12/2019)... ... November 12, 2019 , ... ... proposals from nonprofit U.S. universities and research institutions for its Instrumentation Grant ... of up to $1.2 million per site for the acquisition of instrumentation, development ...
(Date:11/7/2019)... ... November 07, 2019 , ... R3 Stem Cell is now offering ... rest of 2019. The code to use during checkout is FIFTYOFF and applies to ... the nation’s leader in regenerative therapies with over 12,000 successful stem cell procedures performed ...
Breaking Biology News(10 mins):
(Date:11/5/2019)... ... 05, 2019 , ... Focal Healthcare , an innovator ... Fusion Bx 2.0 prostate fusion biopsy solution. By combining information from multiparametric MRI ... give urologists across Europe the ability to perform targeted transrectal and transperineal prostate ...
(Date:11/2/2019)... ... October 31, 2019 , ... ... pharma artificial intelligence pioneer tellic. drug360 brings tellic’s expertise in biomedical language ... allows researchers to quickly uncover relationships between genes, diseases, variants, phenotypes, and other ...
(Date:10/29/2019)... ... October 29, 2019 , ... ... its Silver sponsorship and cold chain validation workshop at the Biomanufacturing World Summit ... San Diego, California. , The Biomanufacturing World Summit brings together pharmaceutical ...
(Date:10/22/2019)... ... ... Catalent, a global leader in clinical supply services, today announced that Ann ... a panel session titled “Cell and Gene Therapy Logistics” at the upcoming Health and ... Oct. 28-30, 2019. , The panel session, on Wednesday, Oct. 30 at 8:30 a.m., ...
Breaking Biology Technology:
Cached News: