HOME >> BIOLOGY >> NEWS
Faster, low cost sequencing technologies needed to drive era of personalized medicine

DNA testing is transforming health care and medicine, but current technologies only give a snapshot of an individual's genetic makeup. Any patient wanting a complete picture of their inherited DNA, or genome, would drop their jaw at the sight of the bill -- to the current tune of $10 million or more charged for every human or mammalian-sized genome sequenced.

Now, with a grant award from the National Human Genome Research Institute (NHGRI), scientists at the Biodesign Institute at Arizona State University are expanding efforts to dramatically lower the cost of DNA sequencing.

The NHGRI, part of the National Institutes of Health (NIH), has set an ambitious target of $1,000 or less - a cost 10,000 times lower than current technology - to make genome sequencing a routine diagnostic tool in medical care. The reduced cost may allow doctors to tailor medical treatments to an individual's genetic profile for diagnosing, treating, and ultimately preventing many common diseases such as cancer, heart disease, diabetes and obesity.

ASU chemist Peiming Zhang and his collaborator Jian Gu have been awarded a $897,000 grant under this program for an ambitious DNA sequencing project that combines physics, chemistry and nanotechnology with engineering. The researchers have been charged with the daunting task of shrinking down the 13 year, $2.7 billion Human Genome Project to days.

"If you want to develop a technology to sequence an individual genome for $1,000, you have to think about using nanotechnology," said Zhang, associate research professor in the Center for Single Molecule Biophysics at the Biodesign Institute. "The technology is available now to pioneer a new approach to sequencing."

Much like the computer industry, DNA sequencing technology is driven by the mantra of faster, cheaper and more reliable. In the past generation, sequencing costs have fallen 100-fold, from roughly a dollar a DNA base to a penny, but
'"/>

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University
30-Jan-2007


Page: 1 2 3

Related biology news :

1. New grants bolster efforts to generate faster and cheaper tools for DNA sequencing
2. Back to the future: Mastodon extends the time limit on DNA sequencing
3. Liverpool amongst first in UK to install unique DNA sequencing technology
4. Discovery could help bring down price of DNA sequencing
5. 454 sequencing identifies HIV drug resistance at early stage
6. Ultra deep sequencing identifies HIV drug resistance at early stage
7. 454 Life Sciences and Baylor College of Medicine complete sequencing of DNA pioneer
8. LSU professor involved in genome sequencing of the first marsupial
9. Latest advances in DNA sequencing highlighted at DOE Joint Genome Institute User Meeting
10. Gene sequencing advance will aid in biomass-to-biofuels conversion
11. Genome sequencing reveals key to viable ethanol production

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/16/2017)...  Veratad Technologies, LLC ( www.veratad.com ), an innovative ... verification solutions, announced today they will participate as a ... thru May 17, 2017, in Washington D.C.,s ... Identity impacts the lives of billions ... evolving digital world, defining identity is critical to nearly ...
(Date:5/6/2017)... 5, 2017 RAM Group , ... new breakthrough in biometric authentication based on a ... properties to perform biometric authentication. These new sensors are ... created by Ram Group and its partners. This sensor ... supply chains and security. Ram Group is a ...
(Date:4/19/2017)... The global military biometrics market ... by the presence of several large global players. The ... major players - 3M Cogent, NEC Corporation, M2SYS Technology, ... 61% of the global military biometric market in 2016. ... military biometrics market boast global presence, which has catapulted ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... ... May 23, 2017 , ... Cambridge Semantics , the ... this year’s Bio-IT World Conference and Expo in Boston May 23-25 with ... solution. The Anzo Smart Data Lake is also a finalist for the Best ...
(Date:5/22/2017)... Baltimore, Maryland (PRWEB) , ... May 22, 2017 ... ... Ted Olsen, joined with other leaders of the Maryland Biohealth community in developing ... a globally recognized Top 3 U.S. BioHealth Innovation Hub by 2023. ...
(Date:5/21/2017)... ... May 20, 2017 , ... CNSDose is a genetically driven, ... process by finding the right antidepressant faster. CNSDose speeds recovery and reduces ... a personalized approach to treatment. , A peer-reviewed and published, 12-week ...
(Date:5/18/2017)... ... May 18, 2017 , ... Dr. Ralph Mobbs ... the Prince Of Wales Private Hospital. The procedure was performed on a 46-year-old ... failed conservative treatments prior to undergoing surgery. , The AxioMed viscoelastic disc is ...
Breaking Biology Technology:
Cached News: