HOME >> BIOLOGY >> NEWS
Faster, low cost sequencing technologies needed to drive era of personalized medicine

DNA testing is transforming health care and medicine, but current technologies only give a snapshot of an individual's genetic makeup. Any patient wanting a complete picture of their inherited DNA, or genome, would drop their jaw at the sight of the bill -- to the current tune of $10 million or more charged for every human or mammalian-sized genome sequenced.

Now, with a grant award from the National Human Genome Research Institute (NHGRI), scientists at the Biodesign Institute at Arizona State University are expanding efforts to dramatically lower the cost of DNA sequencing.

The NHGRI, part of the National Institutes of Health (NIH), has set an ambitious target of $1,000 or less - a cost 10,000 times lower than current technology - to make genome sequencing a routine diagnostic tool in medical care. The reduced cost may allow doctors to tailor medical treatments to an individual's genetic profile for diagnosing, treating, and ultimately preventing many common diseases such as cancer, heart disease, diabetes and obesity.

ASU chemist Peiming Zhang and his collaborator Jian Gu have been awarded a $897,000 grant under this program for an ambitious DNA sequencing project that combines physics, chemistry and nanotechnology with engineering. The researchers have been charged with the daunting task of shrinking down the 13 year, $2.7 billion Human Genome Project to days.

"If you want to develop a technology to sequence an individual genome for $1,000, you have to think about using nanotechnology," said Zhang, associate research professor in the Center for Single Molecule Biophysics at the Biodesign Institute. "The technology is available now to pioneer a new approach to sequencing."

Much like the computer industry, DNA sequencing technology is driven by the mantra of faster, cheaper and more reliable. In the past generation, sequencing costs have fallen 100-fold, from roughly a dollar a DNA base to a penny, but
'"/>

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University
30-Jan-2007


Page: 1 2 3

Related biology news :

1. New grants bolster efforts to generate faster and cheaper tools for DNA sequencing
2. Back to the future: Mastodon extends the time limit on DNA sequencing
3. Liverpool amongst first in UK to install unique DNA sequencing technology
4. Discovery could help bring down price of DNA sequencing
5. 454 sequencing identifies HIV drug resistance at early stage
6. Ultra deep sequencing identifies HIV drug resistance at early stage
7. 454 Life Sciences and Baylor College of Medicine complete sequencing of DNA pioneer
8. LSU professor involved in genome sequencing of the first marsupial
9. Latest advances in DNA sequencing highlighted at DOE Joint Genome Institute User Meeting
10. Gene sequencing advance will aid in biomass-to-biofuels conversion
11. Genome sequencing reveals key to viable ethanol production

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/6/2017)... March 6, 2017 Mintigo , ... today announced Predictive Sales Coach TM , its ... sales intelligence into Salesforce. This unique AI application ... sales organizations with deep knowledge of their customers ... intelligent engagement. Predictive Sales Coach extends Mintigo,s existing ...
(Date:3/2/2017)... Summary This report provides all the information ... partnering interests and activities since 2010. Download the ... Deals and Alliance since 2010 report provides an in-depth ... world,s leading life sciences companies. On demand ... of the most up to date deal and company ...
(Date:3/2/2017)... Australia , March 2, 2017 Australian ... Ltd (ASX: CYP), has signed an agreement with ... from the Monash Biomedicine Discovery Institute and Department of ... to conduct a further preclinical study to support the ... treatment of asthma.  Asthma is a ...
Breaking Biology News(10 mins):
(Date:3/29/2017)... , ... March 29, 2017 , ... ... comprising multiple separable adhesive layers, as issued by the U.S. Patent & Trademark ... it applies to combining electronics and health monitoring. This invention will be critical ...
(Date:3/29/2017)... Pa. , March 29, 2017 Patients ... which is why CSL Behring awards Local Empowerment for ... rare disease patient groups. These groups tackle complex legislative ... heard on Capitol Hill and in statehouses across the ... the community-based grant was awarded to New England Hemophilia ...
(Date:3/29/2017)... and HILDEN, Germany , March 29, 2017 ... PRIME STANDARD: QIA) today announced the U.S. launch of its ... which was cleared by the U.S. Food and Drug Administration as a qualitative ... genomic DNA extracted from EDTA whole blood.* ... The ipsogen JAK2 assay is processed on QIAGEN,s Rotor-Gene ® ...
(Date:3/29/2017)... , March 29, 2017 /PRNewswire/ - Last year,s petition to ... not the only efforts active to generate awareness on the importance ... pharmaceutical drugs in the healthcare market place. ... Earlier this month Health Advance ... distributor of pharmaceutical and nutritional products, announced its endeavors on this ...
Breaking Biology Technology:
Cached News: