HOME >> BIOLOGY >> NEWS
Faster, low cost sequencing technologies needed to drive era of personalized medicine

DNA testing is transforming health care and medicine, but current technologies only give a snapshot of an individual's genetic makeup. Any patient wanting a complete picture of their inherited DNA, or genome, would drop their jaw at the sight of the bill -- to the current tune of $10 million or more charged for every human or mammalian-sized genome sequenced.

Now, with a grant award from the National Human Genome Research Institute (NHGRI), scientists at the Biodesign Institute at Arizona State University are expanding efforts to dramatically lower the cost of DNA sequencing.

The NHGRI, part of the National Institutes of Health (NIH), has set an ambitious target of $1,000 or less - a cost 10,000 times lower than current technology - to make genome sequencing a routine diagnostic tool in medical care. The reduced cost may allow doctors to tailor medical treatments to an individual's genetic profile for diagnosing, treating, and ultimately preventing many common diseases such as cancer, heart disease, diabetes and obesity.

ASU chemist Peiming Zhang and his collaborator Jian Gu have been awarded a $897,000 grant under this program for an ambitious DNA sequencing project that combines physics, chemistry and nanotechnology with engineering. The researchers have been charged with the daunting task of shrinking down the 13 year, $2.7 billion Human Genome Project to days.

"If you want to develop a technology to sequence an individual genome for $1,000, you have to think about using nanotechnology," said Zhang, associate research professor in the Center for Single Molecule Biophysics at the Biodesign Institute. "The technology is available now to pioneer a new approach to sequencing."

Much like the computer industry, DNA sequencing technology is driven by the mantra of faster, cheaper and more reliable. In the past generation, sequencing costs have fallen 100-fold, from roughly a dollar a DNA base to a penny, but
'"/>

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University
30-Jan-2007


Page: 1 2 3

Related biology news :

1. New grants bolster efforts to generate faster and cheaper tools for DNA sequencing
2. Back to the future: Mastodon extends the time limit on DNA sequencing
3. Liverpool amongst first in UK to install unique DNA sequencing technology
4. Discovery could help bring down price of DNA sequencing
5. 454 sequencing identifies HIV drug resistance at early stage
6. Ultra deep sequencing identifies HIV drug resistance at early stage
7. 454 Life Sciences and Baylor College of Medicine complete sequencing of DNA pioneer
8. LSU professor involved in genome sequencing of the first marsupial
9. Latest advances in DNA sequencing highlighted at DOE Joint Genome Institute User Meeting
10. Gene sequencing advance will aid in biomass-to-biofuels conversion
11. Genome sequencing reveals key to viable ethanol production

Post Your Comments:
(Date:6/15/2015)... , June 16, 2015 ... Processing Market by Type (Rule-Based, Statistical, and Hybrid), Technologies ... Forecast to 2020" published by MarketsandMarkets, The Natural Language ... at a CAGR of 18.4% for the forecast period ... and   46 F igures spread   through ...
(Date:6/10/2015)... 2015 According to a ... Technology (Ultrasound, TOF, Structured Light, Stereo Vision), Type(Image, ... and by Geography - Trends & Forecast to ... is expected to reach $3,319.71 Million by 2020, ... and 2020. Browse 71 market data ...
(Date:6/5/2015)... 5, 2015  Intrexon Corporation ("Intrexon") (NYSE: XON ... it has determined the final distribution ratio relating to ... shares of ZIOPHARM Oncology, Inc. ("ZIOPHARM") (NASDAQ: ZIOP ... the distribution date, as a pro rata dividend on ... purchase shares of Intrexon common stock ("Warrants"), outstanding on ...
Breaking Biology News(10 mins):Natural Language Processing Market Worth $13.4 Billion by 2020 2Natural Language Processing Market Worth $13.4 Billion by 2020 3Natural Language Processing Market Worth $13.4 Billion by 2020 4Natural Language Processing Market Worth $13.4 Billion by 2020 53D Sensor Market Worth $3,319.71 Million by 2020 23D Sensor Market Worth $3,319.71 Million by 2020 33D Sensor Market Worth $3,319.71 Million by 2020 4Intrexon Announces Distribution Ratio for Distribution of ZIOPHARM Shares 2Intrexon Announces Distribution Ratio for Distribution of ZIOPHARM Shares 3Intrexon Announces Distribution Ratio for Distribution of ZIOPHARM Shares 4
(Date:6/29/2015)... ... 2015 , ... The global microfluidics market is expected to ... to 2020). The market is mainly driven by the rising geriatric population, growing ... lack of adequate healthcare and research infrastructure in emerging markets, dearth of skilled ...
(Date:6/29/2015)... 2015  Neuralstem, Inc. (NYSE MKT: CUR), a biopharmaceutical ... molecule and cell therapy treatments for central nervous system ... listing on the NASDAQ Capital Market under the symbol ... on the NYSE MKT until the market close on ... is expected to commence on July 13, 2015. ...
(Date:6/29/2015)... , June 29, 2015   For the seventh year ... to assess their overall digital maturity called the ... these companies are not maturing fast enough. While it,s ... in numerous ways overall and customers are increasingly "digital ... of digital customer engagement.  ...
(Date:6/26/2015)... VANCOUVER , June 26, 2015 /PRNewswire/ - iCo ... ICOTF), today announced that all nominees listed in ... as directors at its 2015 Annual Meeting of ... a vote by ballot, the following 5 nominees ... iCo Therapeutics to serve until the Company,s next ...
Breaking Biology Technology:Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 2Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 3Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 4Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 5Neuralstem, Inc. Announces Approval for Listing on the NASDAQ Capital Market 2Neuralstem, Inc. Announces Approval for Listing on the NASDAQ Capital Market 3Results from Digital Maturity Study Show Pharma Lagging 2Results from Digital Maturity Study Show Pharma Lagging 3Results from Digital Maturity Study Show Pharma Lagging 4iCo Therapeutics Announces Voting & Election Results from Annual Meeting of Shareholders 2iCo Therapeutics Announces Voting & Election Results from Annual Meeting of Shareholders 3
Cached News: