HOME >> BIOLOGY >> NEWS
Faster method to create antibodies for disease research

Faster method to create antibodies for disease research British scientists are pioneering a new technique to produce large numbers of antibodies quickly and reliably to help the study of dangerous bacteria. The research, funded by the Biotechnology and Biological Sciences Research Council (BBSRC), is a critical area for study as bacteria such as streptococcus cause deadly blood infections and 'flesh eating bug disease'.

Traditional methods of producing antibodies for research are slow and laborious and pose a significant bottleneck to proteomics research as they can take months of effort. This research offers a potential solution that could produce antibodies in just weeks. Antibodies are vital to the study of proteins as they can bind specifically to a protein of interest and enable researchers to identify, count and track the protein in vitro and in vivo. The study of proteins is important to almost every area of biology as they are often the targets for vaccines, the raw materials for bioprocessing or are employed as environmental biomarkers.

The researchers from Imperial College London at Hammersmith Hospital discovered that a large proportion of antibodies created in response to synthetic peptide immunisation bind to the end of a peptide known as the C-terminus. The unique way that it is presented means that the antibodies will only bind to proteins that contain a precise sequence in their C-terminus.

Dr Rob Edwards, the research leader at Imperial College London, said, "The fact that the antibodies only bind to proteins with the specific sequence in their C-terminus means they are incredibly specific. We started looking at antibodies raised against simple peptide chains comprising just 5 amino acid residues and found that every one these bound only to the target protein."

Dr Edwards commented, "New research in proteomics has already identified thousands of proteins that may be important. We need to be able to study them at a hig
'"/>

Contact: Matt Goode
matt.goode@bbsrc.ac.uk
44-1-793-413-299
Biotechnology and Biological Sciences Research Council
6-Oct-2005


Page: 1 2

Related biology news :

1. Faster-acting antidepressants closer to becoming a reality
2. Faster, low cost sequencing technologies needed to drive era of personalized medicine
3. Faster immune system testing set to improve poultry quality
4. Cost-effective method for gene silencing is featured in Cold Spring Harbor Protocols
5. A new method of adult stem cell growth efficacious in treatment of disorders of the cornea
6. Purdue-IU researchers explore new method for early disease diagnosis
7. Sequencing method yields fuller picture
8. New imaging method clarifies nutrient cycle
9. Researchers discover method for identifying how cancer evades the immune system
10. Bioinformatics-related methods are featured in Cold Spring Harbor Protocols
11. New method for reading DNA sheds light on basis of cell identity

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/3/2019)... ... October 02, 2019 , ... Personalized Stem Cells, ... patient in an FDA approved clinical trial for stem cell treatment of knee ... formation of the company as a subsidiary of VetStem Biopharma. , PSC CEO, Michael ...
(Date:9/30/2019)... ... September 30, 2019 , ... ... mesenchymal stem/stromal cell (hMSC) biomanufacturing systems, today announced it has received patent ... product formats (patent number AU 2015259373). This new patent adds intellectual property ...
(Date:9/25/2019)... ... , ... Deep Science Ventures (DSV), a new paradigm for applied ... of cancer research. , Deep Science Ventures was founded to create a better method ... from the start, both at the industry and biological level. , Through their ...
Breaking Biology News(10 mins):
(Date:10/3/2019)... (PRWEB) , ... October 02, 2019 , ... ... new life sciences leadership firm that is enabling clinical program outsourcing success by ... Founded by award-winning pharma and biotech veteran executive Brenda Reese, phaseUP™ brings clients ...
(Date:10/3/2019)... ... 2019 , ... Rapid Novor, Inc., the world's leader in ... moved into a new, 5000 sqft, purpose-built, state-of-the-art facility. Now home to four ... continuous commitment to quality research and service offerings. , The new ...
(Date:9/24/2019)... ... September 24, 2019 , ... ... of high-level X-ray methods using synchrotron-produced X-rays to study amorphous drug formulations. ... present “Synchrotron X-Ray Diffraction and Pair Distribution Function Analysis of Drug/Polymer Dispersions: ...
(Date:9/24/2019)... ... September 24, 2019 , ... Personalized Stem Cells, ... site qualification for clinical trial sites and physician investigators. The clinical trial ... trial participants. , Clinical trial sites are currently located in San Diego and ...
Breaking Biology Technology:
Cached News: