HOME >> BIOLOGY >> NEWS
Fetal heart-cell enzyme important in onset of heart failure

trols the growth and multiplication of cells. Inpp5f is also related to tumor-suppressor genes involved in cancer.

"HDAC and Inpp5f give us new targets for regulating cardiac hypertrophy," says Epstein. "Inhibitors of HDAC may warrant testing for cardiac disease to stop the hypertrophy that accompanies the re-expression of the fetal-gene program."

HDAC inhibitors are already in trials for cancer and one, valproic acid, has been used for years to treat seizures. Most CHF medications are aimed at regulating blood pressure, but very few are targeted at the heart-muscle cells themselves. About 5 million Americans are living with CHF today, according to the American Heart Association.

"To understand how to better treat heart disease at the cellular level is an important next step," says Epstein.


'"/>

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
18-Feb-2007


Page: 1 2

Related biology news :

1. Fetal exposure to toxins could be behind rise in asthma
2. Choline during pregnancy may avoid, reverse some Fetal Alcohol Syndrome nervous disorders
3. Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
4. 2007-2008 Genzyme/ACMGF Clinical Genetics Fellowship In Biochemical Genetics award winner announced
5. NIEHS researchers identify enzyme critical in DNA replication
6. Scientists discover role of enzyme in DNA repair
7. Researchers create model of cancer-preventing enzyme, study how it works
8. Viral enzyme recruited in fight against ear infection
9. RNA enzyme structure offers a glimpse into the origins of life
10. Researchers create artificial enzyme that mimics the bodys internal engine
11. Scientists identify specific enzymes that make meningitis hard to fight

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Fetal heart cell enzyme important onset heart failure

(Date:5/25/2015)... May 25, 2015  Australia,s market for wearable technologies ... 2014 saw the advent of several trials and prototypes. ... 2015 is expected to ignite interest in wearables as ... Australia . This in turn will spur ... drive new partnerships amongst vendors and distributors. ...
(Date:5/22/2015)... According to a new market ... Thermal, Emotion, Forensic), by Software (Middleware, Databases), by Hardware (Cameras, ... and Home) - Global Forecast to 2020", published by ... in 2015 to $6.19 Billion by 2020, at a ... data Tables and   43 Figures spread through 140 ...
(Date:5/21/2015)... , May 21, 2015 The Sync ... of music for health, today announced a collaborative partnership ... The partnership will center on collaboration on original research, ... first step in the collaboration, The Sync Project and ... "Music as Medicine" in the 2015-2016 academic year.  ...
Breaking Biology News(10 mins):Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 2Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 3Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 4Facial Recognition Market Worth $6.19 Billion by 2020 2Facial Recognition Market Worth $6.19 Billion by 2020 3The Sync Project Announces Partnership with Berklee College of Music's Institute for Creative Entrepreneurship 2The Sync Project Announces Partnership with Berklee College of Music's Institute for Creative Entrepreneurship 3
(Date:5/28/2015)... Research and Markets( http://www.researchandmarkets.com/research/6cg3zw/cell_therapy ) has ... "Cell Therapy - Technologies, Markets and Companies" ... describes and evaluates cell therapy technologies and methods, ... role in the practice of medicine. Hematopoietic stem ... marrow transplants. Role of cells in drug discovery ...
(Date:5/28/2015)... The Academy of Model Aeronautics Foundation will be celebrating the ... National Model Aviation Day was created to celebrate the hobby ... the general public. , The AMA has encouraged all of ... by hosting events in their own communities. More than 80 ... View our online event map to find an event ...
(Date:5/28/2015)... May 28, 2015 Natera, Inc., a ... study published in Ultrasound in Obstetrics & ... (SNP)-based non-invasive prenatal test (NIPT) can identify a ... A study based upon data collected ... occur in about 1 in 1,000 pregnancies, although ...
(Date:5/28/2015)... Dallas, TX (PRWEB) May 28, 2015 ... trade association serving and representing the life sciences ... first Board of Directors meeting at The Foundry ... meeting of the organization brought together a broad ... region, and underscored the organization's early successes in ...
Breaking Biology Technology:Global Cell Therapy Market 2015-2020 - Technologies, Markets and Companies 2Model flying pilots celebrate the Academy of Model Aeronautics Foundation’s Third Annual National Model Aviation Day 2First Confirmed Detection of a Complete Molar Pregnancy with Cell-Free DNA Test 2First Confirmed Detection of a Complete Molar Pregnancy with Cell-Free DNA Test 3BioNorthTX Holds Inaugural Board of Directors Meeting 2BioNorthTX Holds Inaugural Board of Directors Meeting 3
Cached News: