HOME >> BIOLOGY >> NEWS
Finding the origin of fats in fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) leads to liver damage, accumulation of lipids, and liver inflammation in individuals who do not consume, or consume only a little alcohol. If untreated, NAFLD can progress to cirrhosis. The origin of the lipids that accumulate in the liver of these patients was unknown. In a new study appearing in the May 2 print issue of The Journal of Clinical Investigation, Elizabeth Parks and colleagues from the University of Minnesota use stable isotopes to examine the sources of fatty acids that contribute to fatty liver in humans.

The researchers find that accumulated liver lipids come from serum fatty acids, newly made fatty acids within the liver, and dietary fatty acids. These fats build up in NAFLD because the liver is unable to regulate changes in fat metabolism that normally occur when one alternates between fasted and fed states. In an accompanying commentary, Shinji Tamura and Iichiro Shimomura write, "In light of these findings, it seems possible that the reduction of oxidative stress as well as the use of insulin-sensitizing agentsmay prove to be successful treatments for NAFLD."


'"/>

Contact: Stacie Bloom
press_releases@the-jci.org
212-342-4159
Journal of Clinical Investigation
2-May-2005


Page: 1

Related biology news :

1. Finding protection from tumor growth in unexpected places
2. Finding the white wine difference
3. Finding an answer to Darwins Dilemma
4. Finding a cure for cancer: The holy grail of science
5. Finding the right mix: A biomaterial blend library
6. Finding paves way for better treatment of autoimmune disease
7. Finding about cellular microtubule rigidity could lead to development of new nano-materials
8. Findings by Einstein scientists reveal possible strategy against obesity, diabetes and infertility
9. Finding of a new molecular marker of resistance to chemotherapy in breast cancer
10. Finding a cellular Neverland: How stem cells stay childlike
11. Finding a virus is not all bad news

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/3/2016)... England and DE SOTO, Kansas ... , U.S.-based Stroke Detection Plus® to offer Oncimmune,s ... risk assessment and early detection of lung cancer ... large employers, unions and individuals. --> Early ... unions and individuals. --> Oncimmune, a leader ...
(Date:3/2/2016)... , March 2, 2016 ... addition of the "Global Biometrics as ... their offering. --> http://www.researchandmarkets.com/research/cmt3hk/global_biometrics ... "Global Biometrics as a Service Market ... --> Research and Markets ( ...
(Date:3/1/2016)... , March 1, 2016  (RSAC Booth #3041) – ... a whopping $118 billion is lost to false positives, ... and inaccurate fraud detection. At the RSA Conference 2016, ... way companies handle authentication by devaluing the data fraudsters ... analytics. --> --> ...
Breaking Biology News(10 mins):
(Date:5/3/2016)... , ... May 03, 2016 , ... In a list ... out of the state’s 76 fastest-growing private companies; a small percentage of the state's ... ranked organizations on the percent change in revenue from 2012 to 2015. ...
(Date:5/3/2016)... ... May 03, 2016 , ... Kerafast Inc., developers ... from laboratories across the globe, today announced the availability of a Zika virus ... research toward treatment and prevention measures for the Zika virus, the virus’s geographical ...
(Date:5/3/2016)... WOODLANDS, Texas , May 3, 2016  Dr. ... certified plastic surgeon in The Woodlands, Texas ... that destroys 24 percent of treated fat cells in ... and woman. Close to 90 percent of Americans report ... treatment options. Nonsurgical fat reduction procedures are a growing ...
(Date:5/2/2016)... NEW YORK , May 2, 2016 ... company announces that its technology partner Mannin Research Inc. ... and Ophthalmology (ARVO), which takes place from May 1-5, ... Research executives will be meeting with its vendors and ... further explore business development goals and other collaborative opportunities ...
Breaking Biology Technology:
Cached News: